Is it getting slower on your specific wiki or on an empty wiki also?
The only really general advice I have is:
* only have the tiddler you are editing open while editing.
* hide the sidebar (or set it to a the Open tab, but that wouldn't be as effective)
* set the animation duration to 0 (I don't know if that would have any effect on text entry)
* in the tiddler
$:/config/Drafts/TypingTimeout set the value to something higher like 1000
I am not certain that any of those will do much to help, there may also be some plugins that can cause things to slow down, but not many of them do.