Eric,
I moved to Beaufort last year and am out on the marsh casting to reds every time the tides are good to do so. Tonite, in a matter of 45 minutes, I saw 6 fish and had multiple shots at 3 of them but none ate. These really big tides for the next 3-5 days are good and bad. The water rushes in quickly and like tonight, you have a short period of time before there is too much water to see the fish.
There's a club in the Charleston area and I'd be sure that there are some folks in it that are real Red-heads, no pun intended. In addition, Google Earth is one of the best tools for finding a salt marsh to fish.The best ones are fed by a creek from a flat adjoining a large body of water. A Hot Spots map is helpful too. There is also a couple of good fly shops in the area that may steer you in a right direction. The wading season will come to an end in about 2-4 weeks when the fiddler crabs go to hibernation. If you've never waded a salt marsh, CAUTION!!! The taller the grass, the softer the pluff mud. You can wind up up to your knees in mud that you can't get out of. Tread lightly and cautiously. At that time, you'll need a boat or kayak to find em schooled up, at low tide, on the flats. If you make it down this way, drop me a line and we'll wet a line. Our club, The Sea Island Fly Fishers meet on the 2nd Wen of the month at Bay Street outfitter in Beaufort. November 15th we have a casting and how to clinic going on. John M