The answer is no for me but of course that depends on what kind of tools you use.
I wouldnt trust both in a live set-up these days. But macOS is a lot more stable and powerful if you running a lot tools and want to switch applications while live usage.
You might read the thread here about the new iPad CPU spikes with just a few apps which is the worst case in a live set-up (but that might be solved already with the coming update).
Plug-ins are not much more expensive these days if you count the content you might get or buy into complete solutions like Komplete or like you say Mainstage or Logic etc.
I think its mainly about your workflow and preferences. Both options can work or fail in certain things.
Roli is well developed when it comes to Bluetooth MIDI. That is why all their products will communicate with WIDI Master easily. They can pair with a WIDI Master attached to the 5-PIN DIN of your MIDI sampler. The MPE MIDI messages as Roli uses are no problem for WIDI Master as it handles all MIDI messages. So the answer is yes, as long as your MIDI sampler provides power (3.3v or 5v) on the MIDI OUT or THRU to power up the WIDI Master.
USB cables inevitably fail and sometimes one end is reincarnated to power our solderless breadboards. Of course, if the cable broke once, it is waiting to crap out again. Too many have flimsy conductors that cannot withstand any torque and buckle when you push them into a socket. [PROSCH] has a superior answer that only takes a couple of minutes to print and up-cycles a pair of wires with DuPont connectors. The metal tips become the leads and the plastic sheathing aligns with the rim.
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