Hi Ezra,
I am not an expert in Bokeh by any means, but it looks as if it could save you time and code management of the Gizmo d3 plots as main components may already be done for you (it has its own javascript library).
The plots appear to be interactive now and it seems user friendly. In addition, it appears to have powerful capabilities such as WebGL and incorporating with matplotlib and other plotting libraries.
It also enables the user to add custom interactions and many other items which could be very useful.
All in all, definitely looks like it is worth looking into.