Mims 39; Medical Microbiology And Immunology 7th Edition
Hadda Condino
SLE334 allows students to explore aspects of microbiology and immunology relevant to understanding infectious disease. Students will be introduced to medical microbiology and immunology using anthrax as a model disease. Students will learn about biology of bacteria, viral and parasitic pathogens of global importance. The practical experience has been designed to replicate some of the investigative strategies and decision making processes used by medical microbiologists to identify potential pathogenic micro-organisms from various clinical specimens. Many of the techniques students will apply are those commonly used by practicing microbiologists in their routine work. Learning and assessment tasks will enhance the students understanding of infectious diseases, the immune response to infectious disease, diagnosis, the development of candidate vaccines and the identification of pharmacological targets for antimicrobial therapeutics.
mims 39; medical microbiology and immunology 7th edition
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Note: Select the relevant trimester reading list. Please note that a future teaching period's reading list may not be available until a month prior to the start of that teaching period so you may wish to use the relevant trimester's prior year reading list as a guide only.
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to teach future dentists, how to deal with infectious or contaminated material, decontamination, desinfection and sterilisation techniques, guidelines for aseptic work in a oral cavity area, the risks of infections concerning dental treatment, differential diagniosics of infectious diseases with manifestations in a oral cavity, basic strategies in antibiotic therapy. Basics of general and special medical microbiology including pathogenesis of the most important infections and anti-infection immunity mechanisms of the host.
Clem je seznmen posluchačů se zklady obecn a speciln lkařsk mikrobiologie, patogenes nejdůležitějšch onemocněn a zklady jejich diagnostiky, se zklady imunizace a antimikrobiln terapie, s mikroflrou dutiny stn a riziky infekc vyvolanmi touto mikroflrou při stomatologickch zkrocch.
Zskn zkladnch dovednost prce s infekčnm materilem, seznmen s metodami odběru klinickch materilů a interpretac dosažench vsledků.
Předmět tž seznamuje budouc zubaře s metodami dekontaminace, dezinfekce a sterilizace.
Basic properties of bacteria, their virulence factors, pathogenesis of infections. G+ and G- cocci, G+ and G- rods, Mycobacteria, Mycoplasmas, Chlamydiae, Rickettsiae, Spirochets. Basics of medical mycology and parasitology. Desinfection and sterilization, Antimicrobial drugs and strategy of therapy. General and special virology, pathogenesis of viral infections, immune mechanisms of the host, vaccination. HIV, HAV,HBV,HCV,HDV,HEV, Herpesviridae, Neurotropic viruses, Viral diarrhoeas. Respiratory Tract infections, Sexually transmitted infections. Infections with exanthemas and other skin and mucose manifestations. Oral Cavity microbial flora and infection processes. Diagnostic Techniques in medical microbiology.
Microscopy in medical bacteriology, mycology and parasitology. Native, fixed and stained slide. Staining techniques (Gram. Ziehl-Nielsen, Buri, Giemsa, immunofluorescence). Bacterial culture media, cultures and macroscopic morphology. Metabolic Tests (API, Pliva Staphytest, Streptotest, Enterotest) Toxin detection. Antigen detection, Typing. Antibiotic susceptibility tests (diffusion/disc tests, E-tests, MIC, MBC-testing) Serologic reactions( agglutination, precipitation, immunodiffusion, immunofluorescence, ELISA, immunoblot). Genome detection techniques - hybridisation, PCR. Horizontl electrophoresis, real-time PCR. Urine culture and interpreting of the test. Yeast culture (Sabouraud) and GT-test. Sample collection techniques and Kits, documentation, transport requirements. Disinfection and Sterilisation techniques and Sterility control. Blood cultures - proper taking of samples, culture systme icl. BacTec, BactAlert. Anearobic Culture. Anaerostat.
Students practisize collection of their own samples: throat swab, nose swab, urine and transport them to the laboratory. During the week they follow algorithm of routine bacteriological laboratory work-flow hands-on. Additionaly they obtain coded patiens samples: urine, stool, vaginal swab and blood culture. They investigate each sample making different tests. At the end they have to provide results for each sample: Determined pathogen and its sensitivity to antibiotics Additionaly they perform Immunocard tests for different agents: viral or bacterial. They interpret serological tests and detect genome of EBV or CMV using PCR
Zkladn vlastnosti bakteri, nstroje virulence. G+ a G- koky, G+ a G- tyčky, mykobakterie, chlamydie, rickettsie, mykoplasmata, spirochety. Zklady mykologie a parazitologie. Obecn a speciln virologie. Etiologie virovch průjmů, neurotropn viry, HIV. Infekce dchacho systmu, přenosn pohlavnm stykem, infekce s exantmem a dalšmi kožnmi manifestacemi. Mikrobiologick diagnostika, molekulrn diagnostika v mikrobiologii. Mikroorganismy a imunitn systm. Dezinfekce a sterilizace.
Lectures and 2 one-week practical blocks (the 2nd and the 4th week of the semester), with a special focus on microbiology of oral cavity and diagnostic and desinfection techniques.
Lectures and seminars: Inst. of Microbiol.Studničkova 7
Practical blocks: teaching laboratories of the Dept. Microbiology and immunology, Studničkova 7, Ground Floor, Back Entrance.
Přednšky ( ) a seminře věnovan problematice dutiny stn. 2 tden bloky praktickch cvičen seznamujc posluchače ze zkladnmi postupy prce v mikrobiologick laboratoři, se způsoby odběru vzorků klinickch materilů, se strategi identifikace bakteri a strategi antibiotick terapie. Seznm se zsadami požadavků na bakteriologick vyšetřen a se zklady interpretace jeho vsledků, s metodami dezinfekce a sterilizace a způsobem jejich kontroly. Osvojuj si techniky prce s infekčnm materilem při dodržovn zsad bezpečnosti prce.
Prerekvizity: B01129 Biochemie a patobiochemie 1, B01401 Anatomie 2, B01402 Histologie a embryologie 2.
Na praktick cvičen: plšť, obuv na přezut, psac potřeby. Před zahjenm druhho tdnu praktik si každ posluchač vyzvedne v přpravce praktik ndobku na moč a tampn na vtěr z krku. V ponděl si odebere vlastn vzorky a přinese je na praktick cvičen ke zpracovn.