The Medical Subject Headings (MeSH) thesaurus is a controlled and hierarchically-organized vocabulary produced by the National Library of Medicine. It is used for indexing, cataloging, and searching of biomedical and health-related information. MeSH includes the subject headings appearing in MEDLINE/PubMed, the NLM Catalog, and other NLM databases.
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acupuncture: A treatment based on Chinese medicine. Thin needles are inserted into the skin at specific points on the body. This therapy is used to treat pain and various health problems and to reduce stress.
adjuvant therapy: Extra therapy given after a primary treatment, to increase the effectiveness of the primary treatment. For example, using chemotherapy after surgery or radiation treatment for cancer.
adrenaline: Stress hormone that puts the body on high alert. Changes include faster heartbeat, more rapid breathing, greater energy, and higher blood pressure. Also called epinephrine.
advance care directive (or advance medical directive): A legal document that describes the kind of medical care a person want if an accident or illness leaves him or her unable to make or communicate decisions.
aerobic exercise: Physical activity that speeds breathing, improves heart and lung function, and offers many other health benefits. Examples include brisk walking, running, or cycling.
alcohol dependence: A chronic, progressive disease characterized by excessive and often compulsive drinking, impaired control over drinking, use of alcohol despite adverse consequences, and withdrawal symptoms when alcohol use is discontinued. Also known as alcoholism.
alcoholism: Another term for alcohol dependence: A chronic, progressive disease characterized by excessive and often compulsive drinking, impaired control over drinking, use of alcohol despite adverse consequences, and withdrawal symptoms when alcohol use is discontinued. Also known as alcoholism.
allergic rhinitis: A seasonal or year-round allergic condition marked by sneezing, runny nose, and congestion. The most common type of allergy, it is caused by an IgE-mediated immune response to inhaled airborne allergens.
alpha blockers: A group of drugs that lower blood pressure by blocking the effects of adrenaline or adrenaline-like substances on cells' alpha receptors. Also used to treat some prostate gland problems. Alpha blockers are also known as alpha-adrenergic antagonists, alpha-adrenergic blocking agents, and alpha-adrenergic blockers.
angiography: A test that shows how blood moves through the blood vessels and heart. It uses x-rays and the injection of a fluid called a contrast agent that can be seen on the x-rays.
angiotensin II receptor blockers: A class of drugs that blocks the effects of angiotensin. Like ACE inhibitors, they keep coronary arteries open, lower blood pressure, and reduce the heart's workload.
angiotensin-converting enzyme inhibitor: A drug used to treat high blood pressure and congestive heart failure. These drugs stop the production of angiotensin II. This lowers blood pressure and reduces the heart's workload. Usually abbreviated as ACE inhibitor.
ankle-brachial index: A test that compares blood pressure at the ankle with blood pressure at the elbow. A difference between the two indicates the presence of peripheral artery disease.
ankylosing spondylitis: A disease that leads to swelling between the disks of the spine and in the joints where the pelvis and spine meet. Causes back pain and stiffness and can limit movement.
anticoagulants: Drugs that diminish the blood's ability to clot. Anticoagulants are sometimes called blood thinners even though they do not thin the blood. Commonly used anticoagulant drugs include heparin and warfarin.
aortic valve: A valve on the left side of the heart that acts as a one-way gate, opening to allow blood to leave the left ventricle and closing to prevent blood from leaking back into that ventricle.
apraxia: A brain disorder in which a person cannot perform certain actions, such as combing hair, picking up a pencil, or speaking, even though they want to and have the physical ability to do so.
ARB: Abbreviation for angiotensin II receptor blockers, a class of drugs that blocks the effects of angiotensin. Like ACE inhibitors, they keep coronary arteries open, lower blood pressure, and reduce the heart's workload.
arterial resistance: The pressure that the artery walls exert on blood flow; in general, the less elastic the arteries, the greater the arterial resistance and the higher the blood pressure.
arteriosclerosis: A term encompassing a variety of conditions in which artery walls thicken and become less flexible. Sometimes called hardening of the arteries. Arteriosclerosis occurs when cholesterol-rich plaque forms on the inner lining of arteries (atherosclerosis), when artery walls become calcified, or when high blood pressure thickens the muscular wall of arteries.
assisted living: Live-in facilities for adults who need help with certain things, but do not need round-the-clock care. They provide residents with supervision and certain services, such as meals, transportation, or help with dressing, grooming, and other daily activities.
atherosclerosis: The buildup of fatty deposits (plaque) in the walls of arteries, causing narrowing and reduced blood flow; the disease responsible for most heart attacks and many strokes.
atrioventricular node: Also known as the AV node. A major part of the electrical system in the heart that acts as a gateway between the atria and the ventricles. An electrical signal generated by the sinoatrial node (the heart's natural pacemaker) moves through the heart until it reaches the atrioventricular node, a cluster of cells at the bottom of the right atrium. The AV node delays the signal before it is passed to the ventricles. This lets the atria fully contract before the ventricles contract.
atrium: One of the heart's two upper chambers (the plural form is atria). The right atrium receives deoxygenated blood from the body; the left atrium receives oxygenated blood from the lungs.
atypical lobular hyperplasia: An overgrowth of abnormally shaped cells in areas of the breast that produce milk (lobules). atypical lobular hyperplasia is not cancerous but may become cancer.
autonomic nervous system: The part of the nervous system that controls involuntary actions, such as blood pressure or breathing. It also plays an important role in the fight or flight response to danger.
AV node: Abbreviation for atrioventricular node, a major part of the electrical system in the heart that acts as a gateway between the atria and the ventricles. An electrical signal generated by the sinoatrial node (the heart's natural pacemaker) moves through the heart until it reaches the atrioventricular node, a cluster of cells at the bottom of the right atrium. The AV node delays the signal before it is passed to the ventricles. This lets the atria fully contract before the ventricles contract.
balloon angioplasty: A procedure to open clogged heart arteries. A surgeon inserts and inflates a tiny balloon. It widens the blocked artery then expands a small wire mesh tube to keep the artery open.
balloon dilation: A surgical procedure to open a narrowed vessel or tube, such as the urethra, esophagus, or artery. A small, deflated balloon is inserted into the area and inflated to widen it.
barium study: An imaging test that allows doctors to see the inside of the esophagus and upper stomach. It involves swallowing a barium solution, which coats the esophagus and makes it possible for x-rays to see the inside of the intestine.
Barrett's esophagus: The abnormal growth of stomach or small intestine cells in the esophagus, resulting from damage caused by the reflux of stomach acid; occasionally may transform into cancer.
beta blockers: Medications that block epinephrine (adrenaline) and norepinephrine from attaching to certain parts of nerve cells known as beta receptors. Used to treat high blood pressure, heart rhythm problems, migraines, panic attacks, and other conditions.
beta blockers: A class of drugs that slow the heartbeat, lessen the force of each contraction, and reduce the contraction of blood vessels in the heart, brain, and throughout the body by blocking the action of beta-adrenergic substances such as adrenaline (epinephrine) at the beta receptor. Beta blockers, also known as beta adrenergic blocking agents, are used to treat many cardiovascular conditions, including abnormal heart rhythms, angina, and high blood pressure. They also improve survival after a heart attack.
bilevel positive airway pressure: A machine that helps people get more air into their lungs when sleeping by increasing the pressure or force of air when breathing in; often used to treat sleep apnea.
biochemical recurrence: Usually used regarding prostate cancer. It refers to a post-treatment increase in the level of prostate-specific antigen in the bloodstream, indicating that prostate cancer has recurred or spread following the original treatment. Also called biochemical failure.
bypass: A procedure used to divert the flow of blood or other fluids. When referring to the heart, shorthand for coronary artery bypass surgery, used to divert blood flow around a blocked coronary artery.
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