merge k multiple sequence alignments using tcoffee -profile

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Paul Zaharias

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Sep 25, 2020, 5:00:20 AM9/25/20
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Hi,

I'm currently trying to merge 3 or more alignments using the command :

t_coffee -profile alignment1.fasta  alignment2.fasta  alignment3.fasta -output fasta -outfile tcoffee-result.fasta

...but I'm not really satisfied by the resulting alignment - compare to mafftmerge results for example (but mafftmerge is much slower).

Is there a better way of merging 3 or more alignments using tcoffee?

Many thanks
Paul
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