For example the tweet looks like this: username This is a tweet.
If I were to use variable split and a use as splitter a space how do I get to tell tasker to join %var2 %var3...%varx and leave %var1 out?
Bob's method is most efficient, but since you asked...
This would be split by (optional) then action > array pop %var position: 1, next action > join %var joiner:, (a comma).
Using regex with variable search and replace is faster for tasker and more efficient though.
\s+
Check the box labeled, 'one match only' replace with: (optional)