a rich resource for discovering protein-protein interaction

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张飞

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Aug 22, 2011, 11:39:38 PM8/22/11
to 陆续, 张芳源, Ling Zhang, wmj...@163.com, tang...@googlegroups.com, kexuan tang
Hi, there,
Recently, a nice paper has been published on Science. http://www.sciencemag.org/content/333/6042/601
You may have a look at this paper. This paper utilized yeast two hybrid to get a proteome-wide binary protein-protein interaction map for the interactome network of the plant Arabidopsis thaliana containing ~6,200 highly reliable interactions between ~2,700 proteins.  This may give valuable information for your proteins (either enzymes or TFs). You may first get the homologue of your gene in Arabidopsis by blast at NCBI and then search at the following website to see if you can discover some novel interactions with the Arabidopsis homologues. Because the conseved mechanism in different species, such interaction may still happen in your interested species (Artemisia etc.).
Good luck!
Fei
--
Fei Zhang
Postdoctoral Researcher (Million Tadege's lab), Oklahoma State University, Stillwater 74075, OK, USA
Ph.D  from Shanghai Jiao Tong University (Kexuan Tang's lab), No.800 Dongchuan Rd.Shanghai 200240, China
Email: garde...@gmail.com

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