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World's first GM babies born

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Metspitzer

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Jul 17, 2012, 7:24:51 PM7/17/12
to
The world's first geneticallymodified humans have been created, it was
revealed last night.

The disclosure that 30 healthy babies were born after a series of
experiments in the United States provoked another furious debate about
ethics.

So far, two of the babies have been tested and have been found to
contain genes from three 'parents'.

Fifteen of the children were born in the past three years as a result
of one experimental programme at the Institute for Reproductive
Medicine and Science of St Barnabas in New Jersey.

The babies were born to women who had problems conceiving. Extra genes
from a female donor were inserted into their eggs before they were
fertilised in an attempt to enable them to conceive.

Genetic fingerprint tests on two one-year- old children confirm that
they have inherited DNA from three adults --two women and one man.

The fact that the children have inherited the extra genes and
incorporated them into their 'germline' means that they will, in turn,
be able to pass them on to their own offspring.

Altering the human germline - in effect tinkering with the very
make-up of our species - is a technique shunned by the vast majority
of the world's scientists.

Geneticists fear that one day this method could be used to create new
races of humans with extra, desired characteristics such as strength
or high intelligence.

Writing in the journal Human Reproduction, the researchers, led by
fertility pioneer Professor Jacques Cohen, say that this 'is the first
case of human germline genetic modification resulting in normal
healthy children'.

Some experts severely criticised the experiments. Lord Winston, of the
Hammersmith Hospital in West London, told the BBC yesterday:
'Regarding the treat-ment of the infertile, there is no evidence that
this technique is worth doing . . . I am very surprised that it was
even carried out at this stage. It would certainly not be allowed in
Britain.'

John Smeaton, national director of the Society for the Protection of
Unborn Children, said: 'One has tremendous sympathy for couples who
suffer infertility problems. But this seems to be a further
illustration of the fact that the whole process of in vitro
fertilisation as a means of conceiving babies leads to babies being
regarded as objects on a production line.

'It is a further and very worrying step down the wrong road for
humanity.' Professor Cohen and his colleagues diagnosed that the women
were infertile because they had defects in tiny structures in their
egg cells, called mitochondria.

They took eggs from donors and, using a fine needle, sucked some of
the internal material - containing 'healthy' mitochondria - and
injected it into eggs from the women wanting to conceive.

Because mitochondria contain genes, the babies resulting from the
treatment have inherited DNA from both women. These genes can now be
passed down the germline along the maternal line.

A spokesman for the Human Fertilisation and Embryology Authority
(HFEA), which regulates 'assisted reproduction' technology in Britain,
said that it would not license the technique here because it involved
altering the germline.

Jacques Cohen is regarded as a brilliant but controversial scientist
who has pushed the boundaries of assisted reproduction technologies.

He developed a technique which allows infertile men to have their own
children, by injecting sperm DNA straight into the egg in the lab.

Prior to this, only infertile women were able to conceive using IVF.
Last year, Professor Cohen said that his expertise would allow him to
clone children --a prospect treated with horror by the mainstream
scientific community.

'It would be an afternoon's work for one of my students,' he said,
adding that he had been approached by 'at least three' individuals
wishing to create a cloned child, but had turned down their requests

Read more:
http://www.dailymail.co.uk/news/article-43767/Worlds-GM-babies-born.html#ixzz20vQec7mw

Robert Carnegie: Fnord: cc talk-origins@moderators.isc.org

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Jul 17, 2012, 9:10:53 PM7/17/12
to
On Wednesday, July 18, 2012 12:24:51 AM UTC+1, Metspitzer wrote:
> Last year, Professor Cohen said that his expertise would allow him to
> clone children --a prospect treated with horror by the mainstream
> scientific community.
>
> 'It would be an afternoon's work for one of my students,' he said,
> adding that he had been approached by 'at least three' individuals
> wishing to create a cloned child, but had turned down their requests
>
> Read more:
> http://www.dailymail.co.uk/news/article-43767/Worlds-GM-babies-born.html#ixzz20vQec7mw

OMIGOD LOOK AT THEM!

<http://news.bbc.co.uk/1/hi/health/8220553.stm>

Funny, the story mentions the BBC but isn't mentioned /by/ the BBC
News web site, unless it's very old (there is no date) or a hoax.
The latest mention of mitochondria disease from the BBC is in June
<http://www.bbc.co.uk/news/health-18393682>
"The UK's Nuffield Council on Bioethics said the technique could free
children from 'very severe and debilitating disorders'."

The Mail journalist seems to be wildly confused about "the germline".
Mitochondrial DNA and nuclear DNA are separate.

UC

unread,
Jul 17, 2012, 9:29:06 PM7/17/12
to
> Read more:http://www.dailymail.co.uk/news/article-43767/Worlds-GM-babies-born.h...

who wants to be better an make each other a better person. I love to
be outdoors an staying active, either playing sports or boating.
Looking for someone who also takes living a healthy life style a goal.
Like to try all kinds of beers. I am also willing to travel for the
right person.
What I�m doing with my life
I am doing medical sales in Lodi, Ohio an travel all over.
I�m really good at
Being openminded, an making people feel comfortable.
The first things people usually notice about me
Eyes
Favorite books, movies, shows, music, and food
All business books, Steve Jobs bio, John Maxwell.

Country, rap, all types of music.

Crash, Space Balls, comedy central
The six things I could never do without
Good book,
Friends
My dog
Health
Sandy beaches
Family

Richard Norman

unread,
Jul 17, 2012, 9:42:59 PM7/17/12
to
THe work is now 11 years old. See
Mitochondria in human offspring derived from ooplasmic
transplantation: Brief communication
Jason A. Barritt, Carol A. Brenner, Henry E. Malter and
Jacques Cohen
Human Reproduction 1(3) 513-516 (2001)
http://humrep.oxfordjournals.org/content/16/3/513.short

The abstract is where the "germiline" bit comes from. It says: "This
report is the first case of human germline genetic modification
resulting in normal healthy children."

It also says: "Ooplasmic transfer from fertile donor oocytes into
potentially compromised recipient patient oocytes has led to the birth
of nearly 30 babies worldwide. Cytoplasmic transplantation has caused
apprehension, since the mixing of human ooplasm from two different
maternal sources may generate mitochondrial (mt) heteroplasmy (both
recipient and donor mtDNA) in offspring. ... Heteroplasmy was found in
the blood from each of the children."

jillery

unread,
Jul 17, 2012, 11:46:57 PM7/17/12
to
On Tue, 17 Jul 2012 18:29:06 -0700 (PDT), UC
<uraniumc...@yahoo.com> wrote:

[...]

>who wants to be better an make each other a better person.


Why are you spamming topics that you haven't even posted to? Do you
really hate T.O. that much?

Glenn

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Jul 17, 2012, 11:59:56 PM7/17/12
to

"Richard Norman" <rsno...@comcast.net> wrote in message
news:8g4c085cf3t8gv3ph...@4ax.com...
"A frank follow-up of ooplasmic transplantation pregnancies and infants reports
that two out of 17 fetuses had an abnormal 45, XO karyotype. The authors assume
the hypothesis of a link between chromosomal anomalies and oocytes manipulation,
and reveal that one of the babies has been diagnosed at 18 months with Pervasive
Developmental Disorder, a spectrum of autism-related diagnoses."

http://articles.mercola.com/sites/articles/archive/2012/07/17/first-genetically-modified-babies-born.aspx?e_cid=20120717_DNL_artNew_1

I assume that 45 XO karyotype refers to Turner syndrome. Some of the pictures of
those that have the syndrome remind me of what the mermaids looked like that
were found by NOAA scientists. If these children can reproduce, could they
possibly create such unusual body types and novel functions such as mermaids,
and stable, advantageous inheritable traits?


Dana Tweedy

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Jul 18, 2012, 12:06:16 AM7/18/12
to
On 7/17/12 7:10 PM, Robert Carnegie: Fnord: cc
talk-o...@moderators.isc.org wrote:
> On Wednesday, July 18, 2012 12:24:51 AM UTC+1, Metspitzer wrote:
>> Last year, Professor Cohen said that his expertise would allow him to
>> clone children --a prospect treated with horror by the mainstream
>> scientific community.
>>
>> &#39;It would be an afternoon&#39;s work for one of my students,&#39; he said,
>> adding that he had been approached by &#39;at least three&#39; individuals
>> wishing to create a cloned child, but had turned down their requests
>>
>> Read more:
>> http://www.dailymail.co.uk/news/article-43767/Worlds-GM-babies-born.html#ixzz20vQec7mw
>
> OMIGOD LOOK AT THEM!
>
> <http://news.bbc.co.uk/1/hi/health/8220553.stm>
>

I thought they would look like this:


http://pics.livejournal.com/dr_hermes/pic/003efse0


DJT

Glenn

unread,
Jul 18, 2012, 12:19:41 AM7/18/12
to

"Robert Carnegie: Fnord: cc talk-o...@moderators.isc.org"
<rja.ca...@excite.com> wrote in message
news:9228d838-1fa9-47c5...@googlegroups.com...
> On Wednesday, July 18, 2012 12:24:51 AM UTC+1, Metspitzer wrote:
> > Last year, Professor Cohen said that his expertise would allow him to
> > clone children --a prospect treated with horror by the mainstream
> > scientific community.
> >
> > &#39;It would be an afternoon&#39;s work for one of my students,&#39; he
said,
> > adding that he had been approached by &#39;at least three&#39; individuals
> > wishing to create a cloned child, but had turned down their requests
> >
> > Read more:
> >
http://www.dailymail.co.uk/news/article-43767/Worlds-GM-babies-born.html#ixzz20vQec7mw
>
> OMIGOD LOOK AT THEM!
>
> <http://news.bbc.co.uk/1/hi/health/8220553.stm>
>
"Here are your sons, honey. What should we name them?"


Robert Carnegie: Fnord: cc talk-origins@moderators.isc.org

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Jul 18, 2012, 3:30:46 AM7/18/12
to
On Wednesday, July 18, 2012 2:42:59 AM UTC+1, Richard Norman wrote:
> On Tue, 17 Jul 2012 18:10:53 -0700 (PDT), "Robert Carnegie: Fnord: cc
> talk-o...@moderators.isc.org" <rja.ca...@excite.com> wrote:
>
> >On Wednesday, July 18, 2012 12:24:51 AM UTC+1, Metspitzer wrote:
> >> Last year, Professor Cohen said that his expertise would allow him to
> >> clone children --a prospect treated with horror by the mainstream
> >> scientific community.
> >>
> >> 'It would be an afternoon's work for one of my students,' he said,
> >> adding that he had been approached by 'at least three' individuals
Why is the BBC reporting an experiment with monkeys in 2009 if there
were "nearly 30 babies worldwide" born by 2000 by this technique,
turning 12 this year if surviving? Or is that about a different
technique for the same trick?

Robert Carnegie: Fnord: cc talk-origins@moderators.isc.org

unread,
Jul 18, 2012, 3:25:40 AM7/18/12
to
Google thinks this is an excerpt of an entry at <http://�www.okcupid.com/>
which I propose no one investigates further. Why is it here?

Robert Carnegie: Fnord: cc talk-origins@moderators.isc.org

unread,
Jul 18, 2012, 3:53:34 AM7/18/12
to
<http://news.bbc.co.uk/1/hi/sci/tech/1312708.stm>
is a BBC page from 2001.





On Wednesday, July 18, 2012 2:42:59 AM UTC+1, Richard Norman wrote:
> On Tue, 17 Jul 2012 18:10:53 -0700 (PDT), &quot;Robert Carnegie: Fnord: cc
> talk-o...@moderators.isc.org&quot; &lt;rja.ca...@excite.com&gt; wrote:
>
> &gt;On Wednesday, July 18, 2012 12:24:51 AM UTC+1, Metspitzer wrote:
> &gt;&gt; Last year, Professor Cohen said that his expertise would allow him to
> &gt;&gt; clone children --a prospect treated with horror by the mainstream
> &gt;&gt; scientific community.
> &gt;&gt;
> &gt;&gt; &amp;#39;It would be an afternoon&amp;#39;s work for one of my students,&amp;#39; he said,
> &gt;&gt; adding that he had been approached by &amp;#39;at least three&amp;#39; individuals
> &gt;&gt; wishing to create a cloned child, but had turned down their requests
> &gt;&gt;
> &gt;&gt; Read more:
> &gt;&gt; http://www.dailymail.co.uk/news/article-43767/Worlds-GM-babies-born.html#ixzz20vQec7mw
> &gt;
> &gt;OMIGOD LOOK AT THEM!
> &gt;
> &gt;&lt;http://news.bbc.co.uk/1/hi/health/8220553.stm&gt;
> &gt;
> &gt;Funny, the story mentions the BBC but isn&#39;t mentioned /by/ the BBC
> &gt;News web site, unless it&#39;s very old (there is no date) or a hoax.
> &gt;The latest mention of mitochondria disease from the BBC is in June
> &gt;&lt;http://www.bbc.co.uk/news/health-18393682&gt;
> &gt;&quot;The UK&#39;s Nuffield Council on Bioethics said the technique could free
> &gt;children from &#39;very severe and debilitating disorders&#39;.&quot;
> &gt;
> &gt;The Mail journalist seems to be wildly confused about &quot;the germline&quot;.
> &gt;Mitochondrial DNA and nuclear DNA are separate.
>
> THe work is now 11 years old. See
> Mitochondria in human offspring derived from ooplasmic
> transplantation: Brief communication
> Jason A. Barritt, Carol A. Brenner, Henry E. Malter and
> Jacques Cohen
> Human Reproduction 1(3) 513-516 (2001)
> http://humrep.oxfordjournals.org/content/16/3/513.short
>
> The abstract is where the &quot;germiline&quot; bit comes from. It says: &quot;This
> report is the first case of human germline genetic modification
> resulting in normal healthy children.&quot;
>
> It also says: &quot;Ooplasmic transfer from fertile donor oocytes into
> potentially compromised recipient patient oocytes has led to the birth
> of nearly 30 babies worldwide. Cytoplasmic transplantation has caused
> apprehension, since the mixing of human ooplasm from two different
> maternal sources may generate mitochondrial (mt) heteroplasmy (both
> recipient and donor mtDNA) in offspring. ... Heteroplasmy was found in
> the blood from each of the children.&quot;

Looking more closely at the BBC 2009 monkey story seems to answer my question:

"US researchers have previously tried and failed to correct this
defect by adding healthy donated mitochondria into the eggs of
patients wishing to have children.

"But these attempts resulted in birth defects - probably because
mitochondria are so delicate that they are damaged when they are
transplanted from one egg to another.

"As a result, the treatment was banned by the US until it could be
demonstrated that it was safe in animal experiments."

The new technique seems to be to move nuclear DNA into a donor cell
instead of moving mitochondria and mitochondrial DNA.

It occurs to me that the other way, there were bad mitochondria
still in the cell, as well as the introduced good ones.

I still wonder why this wasn't, for instance, on Jacques Cohen's
Wikipedia page, as far as I saw. Censorship?

And is this reading correct?

Desertphile

unread,
Jul 24, 2012, 12:41:38 AM7/24/12
to
On Tue, 17 Jul 2012 19:24:51 -0400, Metspitzer
<Kilo...@deletemecharter.net> wrote:

*CUTS* Please see original


> Geneticists fear that one day this method could be used to create new
> races of humans with extra, desired characteristics such as strength
> or high intelligence.

"Fear?" Isn't this a *GOOD* thing?

> http://www.dailymail.co.uk/news/article-43767/Worlds-GM-babies-born.html#ixzz20vQec7mw

Oh. "The Daily Mail." So it's a lie.


--
"[Denialists] will immediately reject the facts when they glance at them." -- Desertphile
"We will always reject your facts." -- Tunderbar

Bob Casanova

unread,
Jul 24, 2012, 1:43:12 PM7/24/12
to
On Mon, 23 Jul 2012 22:41:38 -0600, the following appeared
in talk.origins, posted by Desertphile
<Deser...@spammegmail.com>:

>On Tue, 17 Jul 2012 19:24:51 -0400, Metspitzer
><Kilo...@deletemecharter.net> wrote:
>
>*CUTS* Please see original
>
>
>> Geneticists fear that one day this method could be used to create new
>> races of humans with extra, desired characteristics such as strength
>> or high intelligence.

>"Fear?" Isn't this a *GOOD* thing?

Could be. Could be otherwise; it would depend on the traits
selected and the motives of the selectors. The concept has
been pretty thoroughly explored in fiction.
Bob C.

"Evidence confirming an observation is
evidence that the observation is wrong."

- McNameless

Glenn

unread,
Jul 24, 2012, 1:51:06 PM7/24/12
to

"Bob Casanova" <nos...@buzz.off> wrote in message
news:lhnt08hkblnbac4uq...@4ax.com...
> On Mon, 23 Jul 2012 22:41:38 -0600, the following appeared
> in talk.origins, posted by Desertphile
> <Deser...@spammegmail.com>:
>
> >On Tue, 17 Jul 2012 19:24:51 -0400, Metspitzer
> ><Kilo...@deletemecharter.net> wrote:
> >
> >*CUTS* Please see original
> >
> >
> >> Geneticists fear that one day this method could be used to create new
> >> races of humans with extra, desired characteristics such as strength
> >> or high intelligence.
>
> >"Fear?" Isn't this a *GOOD* thing?
>
> Could be. Could be otherwise; it would depend on the traits
> selected and the motives of the selectors. The concept has
> been pretty thoroughly explored in fiction.

Yes, as we all know there is no reason to fear the dark since there is no
buggerman out there.

John Stockwell

unread,
Jul 24, 2012, 3:19:49 PM7/24/12
to
On Tuesday, July 17, 2012 5:24:51 PM UTC-6, Metspitzer wrote:
> The world&#39;s first geneticallymodified humans have been created, it was
> revealed last night.
>
> The disclosure that 30 healthy babies were born after a series of
> experiments in the United States provoked another furious debate about
> ethics.
>
> So far, two of the babies have been tested and have been found to
> contain genes from three &#39;parents&#39;.
>
> Fifteen of the children were born in the past three years as a result
> of one experimental programme at the Institute for Reproductive
> Medicine and Science of St Barnabas in New Jersey.
>
> The babies were born to women who had problems conceiving. Extra genes
> from a female donor were inserted into their eggs before they were
> fertilised in an attempt to enable them to conceive.
>
> Genetic fingerprint tests on two one-year- old children confirm that
> they have inherited DNA from three adults --two women and one man.
>
> The fact that the children have inherited the extra genes and
> incorporated them into their &#39;germline&#39; means that they will, in turn,
> be able to pass them on to their own offspring.
>
> Altering the human germline - in effect tinkering with the very
> make-up of our species - is a technique shunned by the vast majority
> of the world&#39;s scientists.
>
> Geneticists fear that one day this method could be used to create new
> races of humans with extra, desired characteristics such as strength
> or high intelligence.
>
> Writing in the journal Human Reproduction, the researchers, led by
> fertility pioneer Professor Jacques Cohen, say that this &#39;is the first
> case of human germline genetic modification resulting in normal
> healthy children&#39;.
>
> Some experts severely criticised the experiments. Lord Winston, of the
> Hammersmith Hospital in West London, told the BBC yesterday:
> &#39;Regarding the treat-ment of the infertile, there is no evidence that
> this technique is worth doing . . . I am very surprised that it was
> even carried out at this stage. It would certainly not be allowed in
> Britain.&#39;
>
> John Smeaton, national director of the Society for the Protection of
> Unborn Children, said: &#39;One has tremendous sympathy for couples who
> suffer infertility problems. But this seems to be a further
> illustration of the fact that the whole process of in vitro
> fertilisation as a means of conceiving babies leads to babies being
> regarded as objects on a production line.
>
> &#39;It is a further and very worrying step down the wrong road for
> humanity.&#39; Professor Cohen and his colleagues diagnosed that the women
> were infertile because they had defects in tiny structures in their
> egg cells, called mitochondria.
>
> They took eggs from donors and, using a fine needle, sucked some of
> the internal material - containing &#39;healthy&#39; mitochondria - and
> injected it into eggs from the women wanting to conceive.
>
> Because mitochondria contain genes, the babies resulting from the
> treatment have inherited DNA from both women. These genes can now be
> passed down the germline along the maternal line.
>
> A spokesman for the Human Fertilisation and Embryology Authority
> (HFEA), which regulates &#39;assisted reproduction&#39; technology in Britain,
> said that it would not license the technique here because it involved
> altering the germline.
>
> Jacques Cohen is regarded as a brilliant but controversial scientist
> who has pushed the boundaries of assisted reproduction technologies.
>
> He developed a technique which allows infertile men to have their own
> children, by injecting sperm DNA straight into the egg in the lab.
>
> Prior to this, only infertile women were able to conceive using IVF.
> Last year, Professor Cohen said that his expertise would allow him to
> clone children --a prospect treated with horror by the mainstream
> scientific community.
>
> &#39;It would be an afternoon&#39;s work for one of my students,&#39; he said,
> adding that he had been approached by &#39;at least three&#39; individuals
> wishing to create a cloned child, but had turned down their requests
>
> Read more:
> http://www.dailymail.co.uk/news/article-43767/Worlds-GM-babies-born.html#ixzz20vQec7mw

There was a particularly vociferous protest from the cannibals of Papua
New Guinea who were calling for a ban on the importation of these GM food
products.

Bob Casanova

unread,
Jul 25, 2012, 2:05:12 PM7/25/12
to
On Tue, 24 Jul 2012 10:51:06 -0700, the following appeared
in talk.origins, posted by "Glenn"
<glenns...@invalid.invalid>:

>
>"Bob Casanova" <nos...@buzz.off> wrote in message
>news:lhnt08hkblnbac4uq...@4ax.com...
>> On Mon, 23 Jul 2012 22:41:38 -0600, the following appeared
>> in talk.origins, posted by Desertphile
>> <Deser...@spammegmail.com>:
>>
>> >On Tue, 17 Jul 2012 19:24:51 -0400, Metspitzer
>> ><Kilo...@deletemecharter.net> wrote:
>> >
>> >*CUTS* Please see original
>> >
>> >
>> >> Geneticists fear that one day this method could be used to create new
>> >> races of humans with extra, desired characteristics such as strength
>> >> or high intelligence.
>>
>> >"Fear?" Isn't this a *GOOD* thing?
>>
>> Could be. Could be otherwise; it would depend on the traits
>> selected and the motives of the selectors. The concept has
>> been pretty thoroughly explored in fiction.
>
>Yes, as we all know there is no reason to fear the dark since there is no
>buggerman out there.

Exactly how does that address any of these posts?
0 new messages