The mac isn't really much of a supported platform outside of its its niche, its also not something you'd really see a lot of in CNC rooms outside of maker labs, so its good someones doing it. but that is hard too because people get really attached to their CAD/CAM/CAE GUI
If you need 4th axis, there are grbl variations that support it, plus its pretty easy to add it in.
We've been building our own PCB CNC too, the othermill is interesting, but i am not sure about its repeat-ability accuracy and building super fine track PCB's, we took a different approach and retro fitted cheap all metal CNC mills, added a new USB controller and an updated grbl codebase, i've also been looking at some of the other variations to grbl. We've got more or less the retrofit ready, i'm just trying to find time working on the software.
Does anyone know what the othermills spindle speed is ?
NX is probably one of the more well known OSX CAD/CAE/'s. but end to end it's definitely hard to find a full solution, though part of my day job is fixing that.