Hello,
8/9 hours is too little time for such a task. Depending on your machine, it will run anywhere from a couple of days to couple of weeks. Unless you are working on a workstation - just forget it :)
Other things to consider: how you foresee the calibration process of your model? How to you foresee the use of such a model?
I can already tel you, that it will be nearly impossible to calibrate such a model (I mean to do a good calibration, ensuring all the processes are adequate, etc).
Next, the model runtime will be, most likely, several hours for ~10 years.
My advise, i) either use a coarser resolution (much coarser), ii) split your model in sub-models, iii) ditch the "standard" tools and use sciprs instead, or iv) brace yourself for a loooong wait on every step (not as long as some numerical models, but still.. I get inpatient and that is saying something ;) ) with an even longer and tedious calibration.
Best,
Natalja