The most common reason for the access denied error is when another application
has already opened the serial port (due to exclusive access). Some applications
(not only dive computer applications) try to open serial ports immediately when
they appear on the system in order to detect their own devices. If you have such
an application running, you have to exit it first, or wait long enough to let it
realize it's not the device it is looking for and release the serial port again.
For the ix3m dive computers, the serial port appears as soon as the USB cable is
connected, but you can only communicate with it after enabling PC mode (System
-> PC mode menu). If you forget to enable PC mode, opening the serial port
should work fine, but you won't get any response from the dive computer.
Certainly not the access denied error you reported.
Jef