Strelka2

[Chris Saunders]

Strelka2 is now available from: https://github.com/Illumina/strelka  This update brings numerous improvements to Strelka's somatic variant caller, notably a random forest variant re-scoring step and a model for normal-sample contamination which we hope will better support liquid and late-stage tumors. The Strelka2 source has been re-licensed to GPLv3 and the package now supports germline calling in small cohorts. Methods and performance details are available in the Strelka2 preprint.

All support and ongoing improvements will be focused on Strelka2. I apologize that this list hasn't been supported for some time, Github issues reported to Strelka2 will be the best way for us support and track items from open-source users going forward.

Looking forward to your feedback on the new release.

-Chris