Ambiguous genitalia is a rare condition where a child is born with outer genitals that do not clearly look either male or female. They may have features of both sexes or not be fully developed. The characteristics of the child's genitals may not match their internal sex organs or their genetic sex.
The genetic sex of a child is determined at conception. The mother's egg cell contains an X chromosome, while the father's sperm cell contains either an X or a Y chromosome. These X and Y chromosomes determine the child's genetic sex.
Normally, an infant inherits 1 pair of sex chromosomes, 1 X from the mother and 1 X or 1 Y from the father. A baby who inherits the X chromosome from the father has 2 X chromosomes and is a genetic female. A baby who inherits the Y chromosome from the father has 1 X and 1 Y chromosome and is a genetic male.
The male and female reproductive organs and genitals both come from the same tissue in the fetus. Ambiguous genitalia can develop if the process that causes this fetal tissue to become "male" or "female" is disrupted. This means the external genitals do look clearly male or female or may have characteristics of both. The physical appearance of people with this condition can vary widely. Very rarely, the physical appearance may be fully developed as the opposite of the genetic sex. For example, a genetic male may have developed the appearance of a female.
With a few exceptions, ambiguous genitalia is most often not life-threatening. However, its treatment has short- and long-term consequences. For this reason, a team of health care professionals with expertise in DSD will work together to understand and treat the child and support the family. This team may include neonatologists, geneticists, endocrinologists, and psychiatrists or social workers. The specific treatment will depend on the specific cause of the ambiguous genitalia.
There have been significant changes in treating ambiguous genitalia. In the past, it was thought that it was best to assign a gender as quickly as possible. This was often based on the external genitals rather than the chromosomal gender. Expert opinion has shifted to understanding that chromosomal, neural, hormonal, psychological, and behavioral factors can all influence gender identity.
Updated by: Anna C. Edens Hurst, MD, MS, Associate Professor in Medical Genetics, The University of Alabama at Birmingham, Birmingham, AL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Editorial update 03/12/24.
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Vertebrates employ varied strategies, both chromosomal and nonchromosomal, to determine the sex of the developing embryo. Among reptiles, temperature-dependent sex determination (TSD) is common. The temperature of incubation during a critical period preceding sexual differentiation determines the future sex of the embryo, presumably by altering the activity or expression of a temperature-dependent regulatory factor(s). Here we examine the expression of the Dmrt1 gene, a candidate regulator of mammalian and avian sexual development, in the turtle. During the sex-determining period, Dmrt1 mRNA is more abundant in genital ridge/mesonephros complexes at male-promoting than at female-promoting temperatures. Dmrt1 is the first gene found to show temperature-dependent expression prior to sexual differentiation, and may play a key role in sexual development in reptiles. genesis 26:174-178, 2000.
Vaginal agenesis (a-JEN-uh-sis) is a rare disorder in which the vagina doesn't develop, and the womb (uterus) may only develop partially or not at all. This condition is present before birth and may also be associated with kidney or skeletal problems.
Vaginal agenesis is often identified at puberty when a female does not begin menstruating. Use of a vaginal dilator, a tubelike device that can stretch the vagina when used over a period of time, is often successful in creating a vagina. In some cases, surgery may be needed. Treatment makes it possible to have vaginal intercourse.
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Typically, the lower portion of these ducts develops into the uterus and vagina, and the upper portion becomes the fallopian tubes. The underdevelopment of the mullerian ducts results in an absent or partially closed vagina, absent or partial uterus, or both.
Females with a missing or partially developed uterus can't get pregnant. If you have healthy ovaries, however, it may be possible to have a baby through in vitro fertilization. The embryo can be implanted in the uterus of another person to carry the pregnancy (gestational carrier). Discuss fertility options with your health care provider.
Copulatory behavior and genital morphology interact to deliver sperm more effectively during mating, but the nature of this interaction has not been explored in depth in most vertebrates. Alpacas have unusually long copulations lasting 15-20 min, and a unique copulatory behavior, where the penis intromits all the way past the cervix, into the uterine horns. Here we describe the morphology of male and female genitalia and report unique morphological characteristics that may be associated with this unusual insemination mode. Vaginal shape is highly variable, and seemingly not associated with age or parity. The cranial vagina varies between bulbous and cylindrical, while the caudal vagina is typically narrower and always cylindrical. The cervix consists of a series of two to three spirals or rings, and it is often found in a relaxed state that may prevent damage caused by the cartilaginous penis tip as it pushes through the cervix to reach the uterine horns. The uterus and uterine horns have a complex shape with multiple constrictions. The cartilaginous penis tip has a sharp urethral process that may help to push against these constrictions. The diameter of the vaginal lumen is much greater than the diameter of the penis suggesting that there is little direct interaction between them, and that female vaginal shape is not under strong copulatory selection. In effect, the entire female reproductive tract of the female is interacting with the penis during copulation.
Okay so, the topic is a bit embarrassing here goes. I know it's DAZ's policy to only sell genitals as part of Pro bundles and on some characters. so my question is, what products specifically to I have to buy to get the basic male genitals for the original Genesis. I ask because a products i recently bought cannot load certain components without it. I get the message says it needs this file "/data/DAZ 3D/Genesis/Male Genitalia/UV Sets/DAZ 3D/Base/default.dsf
I do have some genitals but it seems I need a specific one for this to work.
Thank you.
So I'm expected to re-buy a bunch of stuff I already have to get the rest of the figures. (Gen 1 and 2 Gens.) I guess I'll just stick with using Mike 4 parts and trying to adjust the textures or maybe see if there's a way to re-map the textures that come with most figures to work with Mike 4. Thanks loads DAZ.
No. I'll just make do with Mike 4 parts. If DAZ is going to pull something like this they should have a warning on the stand alone figures and the starter bundles, something like a big flashing red sign that says "This is an incomplete product and you can't get the whole thing without buying a bunch of stuff you don't want." Then maybe they wouldn't make some POed customers who think they've been had. I certainly wouldn't have purchased any of the add-ons to the male figures beyond what comes with Studio had I known this.
PMFJI... not a priority area of interest for me, although generally speaking it's indeed nice to have figures that appear realistic. One thing that really used to get me about Genesis 1 was the glowing, illuminated nostrils! That seems to have been reduced in G2... anyway I wanted to mention that I've looked at, ah, some other web pages where they do various things -- V4 and M4 are shown engaging in, ah, extra-curricular activities on some sites -- and while I might laud the attempts being made I don't think we're there yet, at least not at this price point. At least the screen shots that vendors use (to sell their products and add-ons) don't look all that great in my opinion. Who knows eh... maybe we don't actually WANT to know, I don't know! :-)
When I was just starting out I was bemused to see that Genesis had some, ah, missing parts. Later I was surprised to see that in "Poser Debut" -- which costs around twenty dollars -- you can really wiggle the body parts on one of the included male figures, Jim or James was the name if memory serves.
Only vaguely related btw - did they drop the *dragon* from DS 4.5x, or am I doing something wrong? My latest installation under Win7 64-bit is much better but some things (particularly hair and lots of clothing) didn't install at all. And I don't see the dragon in the Smart Content pane anymore.
Duh... I thought I did. I usually do... maybe I'm thrown off because (A) it's generally getting better, which this time around made for lots more things to play around with, and (B) the apparent clothing problem. I don't have very many clothing or hair items but I do have a few, and some of them didn't seem to install. First time with DIM by the way.
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