Starkly Speaking Reading Group

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All information, schedule of upcoming talks, recordings: https://portal.valencelabs.com/starklyspeaking

Every Tuesday on Zoom at 9am PT / 12pm ET / 6pm CE(S)T: https://zoom.us/j/5775722530?pwd=ZzlGTXlDNThhUDZOdU4vN2JRMm5pQT09

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Slack Workspace for discussions and paper voting: https://join.slack.com/t/logag/shared_invite/zt-2nmy5vsj7-8KEDXe~mU~p5fCxwupSv5w

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Hannes Stärk

12/15/25

Starkly Speaking:

Hi together! Today (in 1h) we will discuss: Speaker: Ben Murrell Department of Microbiology, Tumor

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Starkly Speaking:

Hi together! Today (in 1h) we will discuss: Speaker: Ben Murrell Department of Microbiology, Tumor

12/15/25

Hannes Stärk

12/1/25

Starkly Speaking: Rethinking Molecule Synthesizability with Chain-of-Reaction

Hi together, Today, (in ~3h) we will have: Speaker: Seul Lee who did this work while interning at

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Starkly Speaking: Rethinking Molecule Synthesizability with Chain-of-Reaction

Hi together, Today, (in ~3h) we will have: Speaker: Seul Lee who did this work while interning at

12/1/25

Hannes Stärk

11/24/25

Starkly Speaking: Efficient generation of epitope-targeted de novo antibodies with Germinal

Hi together, In todays reading group session in around 5h we will discuss: Speaker: Talal Widatalla

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Starkly Speaking: Efficient generation of epitope-targeted de novo antibodies with Germinal

Hi together, In todays reading group session in around 5h we will discuss: Speaker: Talal Widatalla

11/24/25

Hannes Stärk

11/16/25

Starkly Speaking: How to build a consistency model: Learning flow maps via self-distillation

Hi together, Tomorrow's session: Speaker: Nicholas Boffi is an assistant professor at CMU. Paper:

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Starkly Speaking: How to build a consistency model: Learning flow maps via self-distillation

Hi together, Tomorrow's session: Speaker: Nicholas Boffi is an assistant professor at CMU. Paper:

11/16/25

Hannes Stärk

11/3/25

BoltzGen Launch Event in San Francisco

Hi together, Join us at our San Francisco launch event for BoltzGen, a new biomolecular binder design

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BoltzGen Launch Event in San Francisco

Hi together, Join us at our San Francisco launch event for BoltzGen, a new biomolecular binder design

11/3/25

Hannes Stärk

10/27/25

Reading group: Protein Hunter: exploiting structure hallucination within diffusion for protein design

Hi together, Join us on Zoom in 10 minutes to discuss with @ChoYehlin about binder design and her

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Reading group: Protein Hunter: exploiting structure hallucination within diffusion for protein design

Hi together, Join us on Zoom in 10 minutes to discuss with @ChoYehlin about binder design and her

10/27/25

Hannes Stärk

10/19/25

Starkly Speaking: Lookup multivariate Kolmogorov-Arnold Networks

Hi together, Tomorrow's session: Speaker: Sergey Pozdnyakov who is a PostDoc at EPFL Paper:

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Starkly Speaking: Lookup multivariate Kolmogorov-Arnold Networks

Hi together, Tomorrow's session: Speaker: Sergey Pozdnyakov who is a PostDoc at EPFL Paper:

10/19/25

Hannes Stärk

10/12/25

Starkly Speaking: Transformers Discover Molecular Structure Without Graph Priors

Hi together, Tomorrow we discuss: Paper: Transformers Discover Molecular Structure Without Graph

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Starkly Speaking: Transformers Discover Molecular Structure Without Graph Priors

Hi together, Tomorrow we discuss: Paper: Transformers Discover Molecular Structure Without Graph

10/12/25

Hannes Stärk

10/6/25

Starkly Speaking: Accelerating Biomolecular Modeling with AtomWorks and RF3

Hi together, In 5 min we start our discussion about: Paper: Accelerating Biomolecular Modeling with

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Starkly Speaking: Accelerating Biomolecular Modeling with AtomWorks and RF3

Hi together, In 5 min we start our discussion about: Paper: Accelerating Biomolecular Modeling with

10/6/25

Hannes Stärk

9/7/25

Starkly Speaking: Amortized Sampling with Transferable Normalizing Flows

Hi together, Tomorrow we will discuss some more unnormalized density sampling! Amortized Sampling

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Starkly Speaking: Amortized Sampling with Transferable Normalizing Flows

Hi together, Tomorrow we will discuss some more unnormalized density sampling! Amortized Sampling

9/7/25

Hannes Stärk2

8/3/25

Starkly Speaking: Adjoint Sampling: Highly Scalable Diffusion Samplers via Adjoint Matching

Ooops, this is not happening in 1 hour as the previous email said. It is happening tomorrow: Every

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Starkly Speaking: Adjoint Sampling: Highly Scalable Diffusion Samplers via Adjoint Matching

Ooops, this is not happening in 1 hour as the previous email said. It is happening tomorrow: Every

8/3/25

Hannes Stärk

7/21/25

Starkly Speaking: Predicting cellular responses to perturbation across diverse contexts with State

Hi together, In 1 hour! Paper: Predicting cellular responses to perturbation across diverse contexts

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Starkly Speaking: Predicting cellular responses to perturbation across diverse contexts with State

Hi together, In 1 hour! Paper: Predicting cellular responses to perturbation across diverse contexts

7/21/25

Hannes Stärk

7/5/25

Starkly Speaking: Next session cancelled

Hey, Our next session's speaker unfortunately cancelled and we will postpone this one. Hannes

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Starkly Speaking: Next session cancelled

Hey, Our next session's speaker unfortunately cancelled and we will postpone this one. Hannes

7/5/25

Hannes Stärk

6/29/25

Starkly Speaking: "UMA: A Family of Universal Models for Atoms"

Hi together, Tomorrow we cover a recent breakthrough paper in the world of NNPs: Paper: UMA: A Family

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Starkly Speaking: "UMA: A Family of Universal Models for Atoms"

Hi together, Tomorrow we cover a recent breakthrough paper in the world of NNPs: Paper: UMA: A Family

6/29/25

Hannes Stärk

6/21/25

Starkly Speaking on Monday: Classifier-Free Guidance: From High-Dimensional Analysis to Generalized Guidance Forms

Hi together, Let us understand a core ingredient of diffusion models better - classifier free

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Starkly Speaking on Monday: Classifier-Free Guidance: From High-Dimensional Analysis to Generalized Guidance Forms

Hi together, Let us understand a core ingredient of diffusion models better - classifier free

6/21/25

Hannes Stärk

6/16/25

Starkly Speaking tomorrow: Boltz-2: Towards Accurate and Efficient Binding Affinity Prediction

Hi together, Tomorrow we discuss Boltz-2! We also have a luma event in case you find that convenient:

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Starkly Speaking tomorrow: Boltz-2: Towards Accurate and Efficient Binding Affinity Prediction

Hi together, Tomorrow we discuss Boltz-2! We also have a luma event in case you find that convenient:

6/16/25

Hannes Stärk2

6/14/25

Starkly Speaking next TUESDAY: Boltz-2: Towards Accurate and Efficient Binding Affinity Prediction

We also have a luma event for the Boltz-2 talk next Tuesday in case you find that convenient: https:/

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Starkly Speaking next TUESDAY: Boltz-2: Towards Accurate and Efficient Binding Affinity Prediction

We also have a luma event for the Boltz-2 talk next Tuesday in case you find that convenient: https:/

6/14/25

Hannes Stärk

6/8/25

Starkly Speaking reading group: Action-Minimization Meets Generative Modeling: Efficient Transition Path Sampling with the Onsager-Machlup Functional

Hi together, Tomorrow we will have: Paper: Action-Minimization Meets Generative Modeling: Efficient

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Starkly Speaking reading group: Action-Minimization Meets Generative Modeling: Efficient Transition Path Sampling with the Onsager-Machlup Functional

Hi together, Tomorrow we will have: Paper: Action-Minimization Meets Generative Modeling: Efficient

6/8/25

Hannes Stärk

6/1/25

Starkly Speaking reading group: Identifying perturbation targets through causal differential networks

Hi together, Tomorrow we will have: Paper: Identifying perturbation targets through causal

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Starkly Speaking reading group: Identifying perturbation targets through causal differential networks

Hi together, Tomorrow we will have: Paper: Identifying perturbation targets through causal

6/1/25

Hannes Stärk

5/25/25

Starkly Speaking reading group: Orbv3 and other models in that class.

Hi together, Tomorrow we will have: Paper: Orbv3 and other models in that class. What is the state of

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Starkly Speaking reading group: Orbv3 and other models in that class.

Hi together, Tomorrow we will have: Paper: Orbv3 and other models in that class. What is the state of

5/25/25

Hannes Stärk

5/18/25

Starkly Speaking reading group: FEAT: Free energy Estimators with Adaptive Transport

Hi together, Tomorrow we will have: FEAT: Free energy Estimators with Adaptive Transport https://

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Starkly Speaking reading group: FEAT: Free energy Estimators with Adaptive Transport

Hi together, Tomorrow we will have: FEAT: Free energy Estimators with Adaptive Transport https://

5/18/25

Hannes Stärk

5/11/25

Starkly Speaking tomorrow: Atom level enzyme active site scaffolding using RFdiffusion2

Hi together, Tomorrow we will have: Paper: Atom level enzyme active site scaffolding using

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Starkly Speaking tomorrow: Atom level enzyme active site scaffolding using RFdiffusion2

Hi together, Tomorrow we will have: Paper: Atom level enzyme active site scaffolding using

5/11/25

Hannes Stärk

5/4/25

No reading group session tomorrow

Hi together, There will be no reading group session tomorrow. Some post ICLR sickness, some models

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No reading group session tomorrow

Hi together, There will be no reading group session tomorrow. Some post ICLR sickness, some models

5/4/25

Hannes Stärk

4/17/25

Starkly Speaking next paper: Towards Fast, Specialized Machine Learning Force Fields: Distilling Foundation Models via Energy Hessians

Hi together, Heyho, we are back with the reading group! New name, new papers :) Next week, Ezra and I

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Starkly Speaking next paper: Towards Fast, Specialized Machine Learning Force Fields: Distilling Foundation Models via Energy Hessians

Hi together, Heyho, we are back with the reading group! New name, new papers :) Next week, Ezra and I

4/17/25

Hannes Stärk

4/6/25

No reading group session tomorrow.

Hi together, There will be no reading group meeting tomorrow. Hannes Stärk Website: https://hannes-

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No reading group session tomorrow.

Hi together, There will be no reading group meeting tomorrow. Hannes Stärk Website: https://hannes-

4/6/25

Hannes Stärk

3/30/25

LoGG tomorrow's paper: Towards Fast, Specialized Machine Learning Force Fields: Distilling Foundation Models via Energy Hessians

Hi together, Tomorrow we enjoy: Towards Fast, Specialized Machine Learning Force Fields: Distilling

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LoGG tomorrow's paper: Towards Fast, Specialized Machine Learning Force Fields: Distilling Foundation Models via Energy Hessians

Hi together, Tomorrow we enjoy: Towards Fast, Specialized Machine Learning Force Fields: Distilling

3/30/25

Hannes Stärk

3/23/25

LoGG tomorrow's paper: One-step Diffusion Models with f-Divergence Distribution Matching

Hi together, Reading group session tomorrow March 24th is at a different time then usual. It will be

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LoGG tomorrow's paper: One-step Diffusion Models with f-Divergence Distribution Matching

Hi together, Reading group session tomorrow March 24th is at a different time then usual. It will be

3/23/25

Hannes Stärk

3/9/25

LoGG tomorrow's paper: Genome modeling and design across all domains of life with Evo 2

Hi together, Tomorrow's paper: Genome modeling and design across all domains of life with Evo 2

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LoGG tomorrow's paper: Genome modeling and design across all domains of life with Evo 2

Hi together, Tomorrow's paper: Genome modeling and design across all domains of life with Evo 2

3/9/25

Hannes Stärk

3/2/25

LoGG tomorrow's paper: The Importance of Being Scalable: Improving the Speed and Accuracy of Neural Network Interatomic Potentials Across Chemical Domains

Hi together, Tomorrow's paper: The Importance of Being Scalable: Improving the Speed and Accuracy

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LoGG tomorrow's paper: The Importance of Being Scalable: Improving the Speed and Accuracy of Neural Network Interatomic Potentials Across Chemical Domains

Hi together, Tomorrow's paper: The Importance of Being Scalable: Improving the Speed and Accuracy

3/2/25

Hannes Stärk

2/23/25

LoGG tomorrow's paper: Inference-Time Scaling for Diffusion Models beyond Scaling Denoising Steps

Hi together, Tomorrow's paper: Inference-Time Scaling for Diffusion Models beyond Scaling

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LoGG tomorrow's paper: Inference-Time Scaling for Diffusion Models beyond Scaling Denoising Steps

Hi together, Tomorrow's paper: Inference-Time Scaling for Diffusion Models beyond Scaling

2/23/25