Yeah, I alphabetize by hand in excel before I import things into Sporcle, so I can sort by last name, when I have people.
For my literature series, I wanted things sorted by title, but that doesn't work if the titles begin with A or An, only The, so I just do everything manually.
For one-word answers, I'll let the Sporcle feature alphabetize answers for me. You don't have a choice in column quizzes, sadly; just not possibly based on how the data works.