Hey,
to replace the windows calculator you can simple rename crunchpad.exe to calc.exe and overwrite the file in your system32 folder. (Perhaps make an backup of the original calc.exe)
If you don't have admin rights or don't want to change files in your system directory you can (probably) still change the function keys on your keypad:
Your keybaord is probable sending the VK_LAUNCH_APP_2 key to the pc
(
http://referencesource.microsoft.com/#WindowsBase/Shared/MS/Win32/NativeMethodsOther.cs,d25b4d1be593e193,references)
The executed program is set in the registry key
"HKLM\SOFTWARE\Microsoft\Windows\CurrentVersion\explorer\AppKey\18".
There you can change the path to speedcrunch.exe and when you click the calculator button speedcrunch will start up (did this myself on my pc :D)
Greets
~ Míkescher