Yes, is discovered and showing but simply nothing happens.
It looks like there is something in the stored profile which it doesn't like so just doesn't run.
If I store another profile (possibly a bit different) I can get a profile for the SDRPlay which always works. I then delete the not working profile and we are happy.
So workaround good, would be nice if it was more robust.
I'm using an HP desktop with 1640T CPU, Win 10 64 bit - under powered but power saving for skimming.