DMT (Dimethyltryptamine)

[J L]

As with most drugs, DMT can affect people in very different ways Trusted Source. Some truly enjoy the experience. Others find it overwhelming or frightening. Some refer to this negative experience as a bad trip.

Regarding its psychoactive effects, people have described feeling like they’re traveling at speed through a tunnel of bright lights and shapes. Others describe having an out-of-body experience and feeling like they’ve changed into something else.

Despite its recreational use, there is interest in the potential therapeutic opportunities of DMT due to its effects on serotonin. Observational studies suggest Trusted Source it could have potential usage in depression, stress, and anxiety

Synthetic DMT usually comes in the form of a white, crystalline powder. Sometimes the drug can have a yellowish or pinkish color.

People can smoke, vaporize, or snort DMT. They can also inject the drug, but this method has additional risks.

When used in religious ceremonies, plants and vines are boiled to create a tea-like drink of varying strengths.

The onset of DMT when inhaling or injecting the drug is rapid. People may experience the drug’s effects within minutes of use. Trusted Source

The intensity and duration of a DMT trip depend on several things, including:

how much you use
how you use it
whether you’ve eaten
whether you’ve taken other drugs
Generally, the effects of inhaled, snorted, or injected DMT last for about 15 to 60 minutes Trusted Source. It typically takes longer to feel the effects of DMT is drinking it in a brew.

DMT is extremely powerful, even though it naturally occurs in several plant species. If you’re going to try it, there are a few steps you can take to reduce your risk for having a bad reaction.

Keep these tips in mind when using DMT:

Strength in numbers: Don’t use DMT alone. Do it in the company of people you trust.
Consider your surroundings: Be sure to use it in a safe and comfortable place.
Take a seat: Sit or lie down to reduce the risk of falling or injury.
Keep it simple: Don’t combine DMT with alcohol or other drugs.
Pick the right time: The effects of DMT can be pretty intense. As a result, it’s best to use it when you’re already in a positive state of mind.
Know when to skip it: Avoid using DMT if you:
are taking antidepressants or another medication associated with serotonin syndrome
are taking a medication that interacts with DMT
have a heart condition
have high blood pressure

DMT can interact with a range of other prescription and over-the-counter medications, as well as other drugs.

If you’re using DMT, you should avoid mixing it with other substances such as:

alcohol
opioids
cocaine
amphetamines
cannabis
LSD, aka acid
mushrooms
ketamine
gamma-hydroxybutyric acid (GHB), aka liquid V and liquid G
Prescription and over-the-counter medications to avoid mixing with DMT include:

opioids
antihistamines
muscle relaxants
vasodilators
blood pressure medications
benzodiazepines
antipsychotics
DMT is extremely powerful, even though it naturally occurs in several plant species. If you’re going to try it, there are a few steps you can take to reduce your risk for having a bad reaction.

Keep these tips in mind when using DMT:

Strength in numbers: Don’t use DMT alone. Do it in the company of people you trust.
Consider your surroundings: Be sure to use it in a safe and comfortable place.
Take a seat: Sit or lie down to reduce the risk of falling or injury.
Keep it simple: Don’t combine DMT with alcohol or other drugs.
Pick the right time: The effects of DMT can be pretty intense. As a result, it’s best to use it when you’re already in a positive state of mind.
Know when to skip it: Avoid using DMT if you:
are taking antidepressants or another medication associated with serotonin syndrome
are taking a medication that interacts with DMT
have a heart condition
have high blood pressure.
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