Modifying recombination map for each group

[Daiki Tagami]

I have a quick question regarding how we can modify recombination map for individuals based on their population.

I am now simulating African and European individuals by using SLiM, and I would ideally like to use to use a different recombination map for those individuals based on their population.

Is there a function that I can use in SLiM to conduct this simulation?

Thank you very much for your help.

Sincerely,

Daiki Tagami

[Ben Haller]

Hi Daiki!  You have two choices.  You can use a recombination() callback to add or remove breakpoints as you wish based upon the subpopulations involved (see the relevant section in the SLiM manual), or you can use a nonWF model, and set the recombination rate map before calling addCrossed() for each offspring.

Cheers,
-B.

Benjamin C. Haller
Messer Lab
Cornell University

--
SLiM forward genetic simulation: http://messerlab.org/slim/
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[Daiki Tagami]

Hi Ben,

Thank you very much for your prompt reply, and it was very helpful for me.

After thinking hard, I decided to use the same approach as the SimHumanity manuscript to simulate individuals, but I might try using the steps that you mentioned as well.

I hope you have a great week!

Sincerely,

Daiki Tagami