Re: [SingleCellBio] Product Announcement of Smart Aliquotor for Single Cell Isolation
Sean Bendall
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Dear Colleague,
It is my great pleasure to announce our first single-cell isolation platform from the Innovative Biochips (iBiochips) Company, “Smart Aliquotor”. The Smart Aliquotor is dedicated to isolate single cells from rare amount of specimen or a complicated biological mixture, with high yield and less effort. The Smart Aliquotor also enables convenient, rapid, identifiable, and damage-free isolation of single cells independent of cell number, size, shape, and motility.
The innovative merits of Smart Aliquotor mainly include;
(1) Easy to use. Liquid handling in the whole process, mainly including loading 100 µL cell suspension into inlet well and collecting sub-µL single-cell suspensions from outlet wells, can be completed only by using a commonly used air displacement pipette (ADP). No complex instrumentation and no additional pre-training is needed for operation.
(2) Easy to isolate and identify single cells. Due to the special design of Smart Aliquotor, 100 µL cell suspension can be uniformly dispensed into 100 outlet wells within 20 seconds. Isolated single cells in outlet wells can be easily identified under common inverted microscope.
(3) Easy to get cell cloning. The single cells isolated into outlet wells are healthy and can proliferate normally within wells to form cloning.
(4) Easy to transfer isolated single cells. The isolated single-cells can be easily retrieved by a ADP and then transferred into standard PCR tubes; or they can be in situ lysed within the outlet wells, followed by the transfer of single-cell lysate into PCR tubes for mRNA analysis, eliminating the risk of cell loss during transfer.
(5) Easy to isolate single adherent cells. After isolation into outlet wells, single cells are allowed to adhere to substrate surface, therefore, the Smart Aliquotor can be used to isolate single adherent cells based on their size and morphology, providing a potential way to study genotype-phenotype correlation at the single-cell level.
(6) Easy to isolate rare cells from extremely high cell population. The Smart Aliquotor enables highly efficient enrichment and rapid isolation of a target cell from millions of cells, suitable for isolation of extremely rare cells including circulating tumor cells from blood.
(7) High compatibility. Both single eukaryocyte cells and single prokaryotic cells with diameters from 1 μm to 50 μm can be effectively isolated into outlet wells of ≤1 μl volume in the Smart Aliquotor independent of cell shape and motility.
In short, Smart Aliquotor is assisting single-cell isolation and accelerating both single-cell clonal and genetic analysis.
The facility of iBiochips includes a class 100 cleanroom certified GMP (Good Manufacturing Practice), microscopy room, cell/tissue culture room, and product design suite. The technological innovations of iBiochips are truly based on clinical needs.
For more information, please check the brief introduction of Smart Aliquotor attached or visit our website at http://ibiochips.com.
Best regards,
Myeong Chan Jo, Ph.D.
Innovative Biochips, LLC
9350 Kirby Drive, Suite 200, Houston, TX 77054, USA
+1 (832) 538-1925 | mc...@ibiochips.com | http://ibiochips.com
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Fisher, Stephen A
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Stephen Fisher, PhD
Biology Department
University of Pennsylvania
Jiang F. Zhong
We have a opening for postdoc at University of Southern California, Los Angeles
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John
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Sent: Thursday, February 9, 2017 10:52:00 AM
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