In the ending of the anime, both of them ended up separated and then
at the end of the credits, they run into each other again. In the end
of the manga however, they spend eternity together.
Opinions on which ending does one prefer?
As far as cannon relationships go
Kashimashi (Girl meets Girl)
Simoun
ICE (OVA)
Strawberry Panic
Maria Sama ga Miteru --First season, Spring, and all OAVs
just to name a few