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Physical Biology of the Cell is a textbook appropriate for a first course in physical biology or biophysics for either undergraduate or graduate students. It maps the huge and complex field of cell and molecular biology from the distinct perspective of physical biology.By organizing ideas and data based on proximity in physical biology space we can study topics that are not obviously related in cell biology space. This organizational principle is the central thesis of the book: the appropriate application of a relatively small number of fundamental physical models can serve as the foundation of whole bodies of quantitative biological intuition, broadly useful across a wide range of biological problems.The much-anticipated full-color Second Edition includes new features and resources and is available in a variety of e-book formats.