It can be if you're using a form, which is not my case. I need to respond to several changes in lots of field types.
Knockout seems to make sure the bindings work the same way across browsers, but this is not the case with Serenade.
For example, try to add a class to some div depending on some attribute that will change its background color.
Then bind that attribute to a checkbox and you'll see that the background will change only when the checkbox loses the focus in IE 8.
It is too much work to handle such differences individually for each browser and it goes against the usage of some library for helping us to write consistent code that will work the same way across supported browsers.
Could you please reconsider a consistent binding behavior across browsers, taking into account that they will trigger their events in different ways?