Depth ratio of 0.5 - noisy data

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Aug 20, 2023, 7:12:18 AM8/20/23

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Hi,

I've been running the standard Sequenza pipeline and it works pretty well.

For some of the samples (normal-tumor pairs), the genome view shows several CN alterations (too noisy) and a depth.ratio of ~ 0.5 (see attached).

Does it mean that I have contamination? any suggestions please?

Thank you,

Hashem

Screen Shot 20230820_sequenza.png

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