You can move 'database' and 'exe' folders to the folder containing this new version such that you don't need to re-download anything. If you used 'svn checkout' to get SeqMule previously, just 'svn update' to update all scripts and './Build install' again.
Major changes are listed below:
1. Users now can supply multiple samples, eg.,
seqmule -1 fa_pe_1.fq,mo_pe_1.fq -2 fa_pe_2.fq,mo_pe_2.fq -p father,mother -a advanced_config
Please make sure the order is consistent between -1 and -2 arguments.
2. The union of variants from different VCF/AVINPUT files can be produced. Some problems with Venn diagram, and consensus call extraction have been fixed.
3. By default, SeqMule can automatically detect Phred score scheme now.
4. Some perl module dependencies have been removed for easier installation. The tradeoff is that SeqMule will rely heavily on Linux utilities.
Happy Sequencing!
Yunfei