API sets on the v1.0 endpoint ( ) have reached general availability (GA), and have gone through a rigorous review-and-feedback process with customers to meet practical, production needs. Updates to APIs on this endpoint are additive in nature and don't break existing app scenarios.
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The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.
The study of metagenomics has been much benefited from low-cost and high-throughput sequencing technologies, yet the tremendous amount of data generated make analysis like de novo assembly to consume too much computational resources. In late 2014 we released MEGAHIT v0.1 (together with a brief note of Li et al. (2015) [1]), which is the first NGS metagenome assembler that can assemble genome sequences from metagenomic datasets of hundreds of Giga base-pairs (bp) in a time- and memory-efficient manner on a single server. The core of MEGAHIT is an efficient parallel algorithm for constructing succinct de Bruijn Graphs (SdBG), implemented on a graphical processing unit (GPU). The software has been well received by the assembly community, and there is interest in how to adapt the algorithms to integrate popular assembly practices so as to improve the assembly quality, as well as how to speed up the software using better CPU-based algorithms (instead of GPU). In this paper we first describe the details of the core algorithms in MEGAHIT v0.1, and then we show the new modules to upgrade MEGAHIT to version v1.0, which gives better assembly quality, runs faster and uses less memory. For the Iowa Prairie Soil dataset (252Gbp after quality trimming), the assembly quality of MEGAHIT v1.0, when compared with v0.1, has a significant improvement, namely, 36% increase in assembly size and 23% in N50. More interestingly, MEGAHIT v1.0 is no slower than before (even running with the extra modules). This is primarily due to a new CPU-based algorithm for SdBG construction that is faster and requires less memory. Using CPU only, MEGAHIT v1.0 can assemble the Iowa Prairie Soil sample in about 43h, reducing the running time of v0.1 by at least 25% and memory usage by up to 50%. MEGAHIT v1.0, exhibiting a smaller memory footprint, can process even larger datasets. The Kansas Prairie Soil sample (484Gbp), the largest publicly available dataset, can now be assembled using no more than 500GB of memory in 7.5days. The assemblies of these datasets (and other large metgenomic datasets), as well as the software, are available at the website -bal.github.io/megabox.
ADaMIG v1.0 specifies ADaM standard dataset structures and variables, including naming conventions. It also specifies standard solutions to implementation issues. The ADaMIG must be used in close concert with ADaM v2.1
Version 1.0 of the Standard for Exchange of Nonclinical Data Implementation Guide: Animal Rule (SENDIG-AR) describes how to represent data for studies submitted under FDA regulations commonly known as the Animal Rule. The Animal Rule provides a regulatory mechanism for the approval of drugs and licensure of biological products when human efficacy studies are not ethical or feasible.
SENDIG-AR v1.0 is based upon, and should be used in close concert with, Version 1.8 of the Study Data Tabulation Model (SDTM) and Version 3.1 of the CDISC Standard for Exchange of Nonclinical Data Implementation Guide (SENDIG). Although the SENDIG v3.1 is based on SDTM v1.5, any data submitted under the Animal Rule should follow the conventions used in this implementation guide, and be based on SDTM v1.8.
As the circular economy grows in momentum, it is imperative for companies to prepare for their transition based on insights into their circular performance and associated risks and opportunities. To do this, business needs a universal and consistent way to measure its circularity.
The CTI process helps companies to scope and prepare the assessment and interpret its results, understand its risks and opportunities, prioritize actions and establish SMART targets to monitor progress.
The CTI is inward-facing, objective, quantitative and based on demonstrable data. This data may sit in hidden corners of the company or even outside the company, with its value chain partners. In order to support and guide companies through this process, we have partnered with Circular IQ to develop the CTI online tool available at www.ctitool.com.
We invite companies of all sizes and industries worldwide to demonstrate their commitment to the circular economy by measuring their circular baseline guided by the CTI and supported by its online tool.
The Circular Transition Indicators v1.0, v2.0 and v3.0, by the World Business Council for Sustainable Development are licensed under CC BY-ND 4.0 (Creative Commons Attribution-NoDerivatives 4.0 International).
The stable release of the SLSA 1.0 Build Track lowers the barrier of entry for improvements, helps you focus efforts on improving your build, and reduces the chances of tampering across a large swath of the supply chain.
At IBM, belief in the power of Open Innovation is driving our current actions and future plans. That is why we have been actively contributing to the Supply chain Levels for Software Artifacts (SLSA) v1.0 specification. By openly collaborating with the OpenSSF community to provide build integrity clarity, package consistency, and adopt-ability at scale, we are certain this framework will help software developers restrict tampering, improve integrity, and better secure packages and infrastructure in software supply chains.
As we continue to enhance the security of how npm packages are built, the SLSA framework has served as a launchpad for us in determining what capabilities to provide. It has been instrumental in moving forward the security of open source packages in a way that makes sense for users, open source maintainers, and vendors.
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The first fully working version (v1.0) is now available. The big change is you can now define what pins of the Arduino are used, no longer are you tied to pins 10-13. Also, vibration (Rumble) and analog button pressure readings (how hard is a button being pressed) are now working. The library has changed names. PSX -> PS2X to avoid confusion with other sets of code. Sorry for those that need to change a bunch of their programs.
The Lynxmotion adapter may not follow the color wiring diagram below. Instead, it might follow this diagram. (Lynxmotion only). Be careful and use a volt meter to confirm pin positions.
On behalf of Kubernetes SIG Network, we are pleased to announce the v1.0 release of GatewayAPI! This release marks a huge milestone forthis project. Several key APIs are graduating to GA (generally available), whileother significant features have been added to the Experimental channel.
This release includes the graduation ofGateway,GatewayClass, andHTTPRoute to v1, whichmeans they are now generally available (GA). This API version denotes a highlevel of confidence in the API surface and provides guarantees of backwardscompatibility. Note that although, the version of these APIs included in theStandard channel are now considered stable, that does not mean that they arecomplete. These APIs will continue to receive new features via the Experimentalchannel as they meet graduation criteria. For more information on how all ofthis works, refer to the Gateway API VersioningPolicy.
Gateway API now has a logo! This logo was designed through a collaborativeprocess, and is intended to represent the idea that this is a set of KubernetesAPIs for routing traffic both north-south and east-west:
Historically, Gateway API has bundled a validating webhook as part of installingthe API. Starting in v1.0, webhook installation is optional and only recommendedfor Kubernetes 1.24. Gateway API now includesCEL validation rules aspart of theCRDs.This new form of validation is supported in Kubernetes 1.25+, and thus thevalidating webhook is no longer required in most installations.
This release was primarily focused on ensuring that the existing beta APIs werewell defined and sufficiently stable to graduate to GA. That led to a variety ofspec clarifications, as well as some improvements to status to improve theoverall UX when interacting with Gateway API.
Most of the changes included in this release were limited to the experimentalchannel. These include HTTPRoute timeouts, TLS config from Gateways to backends,WebSocket support, Gateway infrastructure labels, and more. Stay tuned for afollow up blog post that will cover each of these new features in detail.
The idea of Gateway API was initially proposed4 years ago at KubeCon San Diego as the next generationof Ingress API. Since then, an incredible community has formed to develop whathas likely become the most collaborative API in Kubernetes history. Over 170people have contributed to this API so far, and that number continues to grow.
Unlike other Kubernetes APIs, you don't need to upgrade to the latest version ofKubernetes to get the latest version of Gateway API. As long as you're runningone of the 5 most recent minor versions of Kubernetes (1.24+), you'll be able toget up and running with the latest version of Gateway API.
One of our key goals going forward is to work to stabilize and graduate otherexperimental features of the API. These include support for servicemesh, additional route types(GRPCRoute,TCPRoute,TLSRoute,UDPRoute),and a variety of experimental features.
We've also been working towards movingReferenceGrant intoa built-in Kubernetes API that can be used for more than just Gateway API.Within Gateway API, we've used this resource to safely enable cross-namespacereferences, and that concept is now being adopted by other SIGs. The new versionof this API will be owned by SIG Auth and will likely include at least somemodifications as it migrates to a built-in Kubernetes API.
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