Dr. Are is Jerald L & Carolynn J. Varner Professor of Surgical Oncology & Global Health; Vice Chair of Education; Program Director, General Surgery Residency, University of Nebraska Medical Center, Omaha.
For the convenience of the reader, each issue will focus on one country from one of the six regions of the world as defined by the World Health Organization (ie, Africa, the Americas, South-East Asia, Europe, Eastern Mediterranean, and Western Pacific). Each section will focus on the general aspects of the country followed the current and predicted rates of incidence and cancer-related mortality.
Bangladesh, a South Asian country located to the east of India on the Bay of Bengal, has a population of 156 million (8th most populated country in the world). With 1,074 people per square kilometer, Bangladesh is also one of the most densely populated countries.
Since the country gained independence from Pakistan in 1971, it has been affected by environmental and economic issues. Nearly 31.5% of the population in Bangladesh lives below the poverty level. Despite this fact, Bangladesh now has the 31st highest economic growth worldwide, with a 6.2% average annual increase in gross domestic product.
Cancer is the 6th leading cause of death and accounts for 10% of all mortality in Bangladesh. Based on two hospital-based cancer registries, nearly 66% of patients with cancer are estimated to be within the age bracket of 30 to 65 years and constitute the main workforce structure in the country.
Breast, esophageal, and cervical cancers are the most common cancers by incidence in Bangladesh. However, esophageal, lung, and pharyngeal cancers account for the highest rates of cancer-related mortality. The incidence of cancers is expected to rise from 136,719 cases in 2015 to 250,726 cases in 2035.
Lung cancer is the most common cancer in men in Bangladesh, and 48.3% of men smoke tobacco. With tobacco being one of the most important modifiable cancer risk factors, Bangladesh has implemented an action plan for tobacco control.
Breast cancer is the most common cancer in women in Bangladesh. Despite this fact, the most basic preventive services (breast palpation) are not universally available at the primarily health-care level. However, efforts are underway to improve education and awareness on self-breast examination. With a high rate and mortality from esophageal and pharyngeal cancers, educational efforts on mouth self-examination are also underway.
Bangladesh has several nutritional health hazards likely contributing to the current cancer burden. Millions of people in Bangladesh have been exposed to arsenic, a well-known carcinogen, due to groundwater contamination. There are also concerns about carcinogens in the food supply, with the use of formalin in several foods and dichlorodiphenyltrichloroethane (DDT) in dried fish to name a few.
The prevalence of obesity in Bangladesh is quite low, at 3.3%. This rate is likely due to the high percentage (16.4%) of the population consuming a suboptimal amount of nutrition for minimal energy expenditure.
With less than 1 hospital bed (0.6) and physician (0.36) per 1,000 people, Bangladesh is generally not able to provide adequate treatment facilities for cancer management. Bangladesh spends 2.8% of its gross domestic product on health care, which is the 10th lowest in the world. There is a severe shortage of radiation therapy machines and trained oncologists in Bangladesh. According to the World Health Organization (WHO), radiotherapy and chemotherapy are generally available in the public health system, but oral morphine and home health care for people with advanced-stage cancer are not generally available.
The page could not be loaded. The CMS.gov Web site currently does not fully support browsers with"JavaScript" disabled. Please enable "JavaScript" and revisit this page or proceed with browsing CMS.gov with"JavaScript" disabled.Instructions for enabling "JavaScript" can be found here.Please note that if you choose to continue without enabling "JavaScript" certain functionalities on this website may not be available.
The Centers for Medicare & Medicaid Services (CMS) has determined that the evidence is sufficient to cover supervised exercise therapy (SET) for beneficiaries with intermittent claudication (IC) for the treatment of symptomatic peripheral artery disease (PAD). Up to 36 sessions over a 12 week period are covered if all of the following components of a SET program are met:
Beneficiaries must have a face-to-face visit with the physician responsible for PAD treatment to obtain the referral for SET. At this visit, the beneficiary must receive information regarding cardiovascular disease and PAD risk factor reduction, which could include education, counseling, behavioral interventions, and outcome assessments.
Throughout this document we use numerous acronyms, some of which are not defined as they are presented in direct quotations. Please find below a list of these acronymsand corresponding full terminology:
AACVPR - American Association of Cardiovascular and Pulmonary Rehabilitation
ABI - Ankle-Brachial Index
ACC - American College of Cardiology
ACD - Absolute Claudication Distance
ACCF - American College of Cardiology Foundation
ACR - American College of Radiology
AHA - American Heart Association
AHRQ - Agency for Healthcare Research and Quality
APTA - American Physical Therapy Association
ASA - American Stroke Association
AWD - Absolute Walking Distance
CAD - Coronary Artery Disease
CBVD - Cerebrovascular Disease
CCCQ - Charing Cross Claudication Questionnaire
CEPA - Clinical Exercise Physiology Association
CLAU-S - Claudication Scale
CMS - Centers for Medicare & Medicaid Services
COT - Claudication Onset Time
CVC - Cardiovascular Coalition.
ER - Endovascular Revascularization
FCD - Functional Claudication Distance
FDA - Food and Drug Administration
IC - Intermittent Claudication
ICD - Initial Claudication Distance
M - Meters
MEDCAC - Medicare Evidence Development & Coverage Advisory Committee
MNACVPR - Minnesota Association of Cardiovascular and Pulmonary Rehab
MWD - Maximal Walking Distance
MWT - Maximal Walking Time
NCA - National Coverage Analysis
NCD - National Coverage Determination
OMC - Optimal Medical Care
PAD - Peripheral Artery Disease
PAQ - Peripheral Artery Questionnaire
PFWD - Pain Free Walking Distance
PFWT - Pain Free Walking Time
PTA - Percutaneous Transluminal Angioplasty
PWT - Peak Walking Time
QoL - Quality of Life
RCT - Randomized Controlled Trial
SE - Supervised Exercise
SEP - Supervised Exercise Program
SET - Supervised Exercise Therapy
SCAI - Society for Cardiovascular Angiography and Intervention
SIR - Society of Interventional Radiology
ST - Stent Revascularization
SVM - Society for Vascular Medicine
SVS - Society for Vascular Surgery
UE - Unsupervised Exercise
US - United States
VASQoL - Vascular Quality of Life Questionnaire
VIVA - Vascular Interventional Advances
WA - Walking Advice
WIQ - Walking Impairment Questionnaire
PAD is a vascular disease that stems from atherosclerosis (plaque buildup) which narrows the arteries affecting the lower extremities. The number of people diagnosed with PAD is estimated at more than 200 million worldwide, with approximately 12% of Americans having PAD (Ostchega, Paulose-Ram, Dillon, Gu, & Hughes, 2007; Vun, Miller, Delaney, Allen, & Spark, 2016). The presence of PAD becomes more prevalent with age, with PAD affecting more than 10% of patients in their 60s and 70s (Criqui, 2015). The diagnosis of PAD can be confirmed through the ankle-brachial index (ABI), which is the ratio of systolic pressure at the ankle to that in the arm, or the toe-brachial index for patients where ABI is not reliable due to noncompressible vessels, common for patients of advanced age or chronic diabetes (Anderson et al., 2013; Fowkes et al., 2013). ABI results of 0.91 to 0.99 are considered borderline, with an ABI of 0.90 or less considered abnormal (Anderson et al., 2013).
PAD is an underdiagnosed disease with debilitating consequences that disproportionately affects minority populations. Research has shown SET to be an effective, minimally invasive method to alleviate the most common symptom associated with PAD. This could also prevent the progression of PAD and lower the risk of cardiovascular events that are prevalent in these patients.
Practice guidelines from the American College of Cardiology Foundation/American Heart Association (ACCF/AHA) recommend SET as the initial treatment for patients suffering from IC (Gerhard-Hermanet al., 2016). While experts seem to agree that exercise therapy should be the initial treatment for PAD/IC, the number of endovascular revascularization (ER) procedures has been increasing (Spronk et al., 2008). The preference of physicians and patients for the more invasive ER treatment can be partly attributed to the limited access to SET programs, and the immediate result that is observed with ER (Spronk et al., 2008; van den Houten et al., 2016). ER has remained a more popular treatment option for claudication than SET, despite the ACCF/AHA recommendation that ER be reserved for cases where the patient is too functionally impaired for SET (Anderson et al., 2013).
b1e95dc632