"Lyme Disease" vs Scientific Evidence

[Mort Zuckerman]

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Subject: "Lyme Disease" vs Scientific Evidence

Date: Jun 6, 2010 2:09 PM

Medical Jerk Pretends He Knows What He's Talking
About, Below
===================================================

Actually,

THE "TWO-TIERED" TESTING WAS A CRIME SCENE:
1) Lyme testing is a scientific crime scene
http://www.actionlyme.org/ELISA_ARBITRARY_CUTOFF.htm
and no one agreed with Allen Steere, most
particularly, Gary Wormser, about Steere's
Dearborn "case definition" proposal:
http://www.actionlyme.org/DEARBORN_WHO_SAID_WHAT.htm
Yet, all of the so-called evidence based
treatment trials (of which there was 1, Klempner's)
were conducted on the basis that a Steere "case" was
a case:
http://www.actionlyme.org/MKLEMPNER.htm
Klempner never reported ^^^ his primers in
the Methods and Material Section, because
no one at Mass Med knows how science is done.


LAWSUITS OVER THE HLA-LINKED "CASE DEFINITION":
2) Does everyone recall that Steve Sheller
(Sheller.com) sued SmithKline in a class action
specifically because SmithKline (Yale) did not reveal
that people with Steere's Special haplotypes should
not be vaccinated?
http://www.ncbi.nlm.nih.gov/pubmed/2078208

The New, Dearborn definition of "Lyme Disease"
meant "Only an Autoimmune, HLA-linked Bad-Knee,"
as everyone will recall. The whole effort was
about not treating anyone. Thus, it is obvious
that if insurance companies could get some medical
whores to say "Lyme is an autoimmune-knee," "no one
needs antibiotics, no one needs to be supervised
by an MD, and no one, most of all, needs that
$100,00 a year IV ceftriaxone treatment :)))"
http://www.actionlyme.org/CRYME_DISEASE.htm

Is Allen Steere a dope? Allen Steere is a dope.
Look at this report. It looks like it was written
by some scientific RETARD:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC423723/pdf/jcinvest00109-0086.pdf


TAXONOMICALLY, "RELAPSING FEVER" IS THE DISEASE'S
REAL NAME:
3) "Lyme Disease" is a straw man.
http://www.actionlyme.org/IDSA_III_STRAWMAN.htm
A joke.
A hoax.
It's real name is Relapsing Fever.
"Lyme Disease" is PsyOps for the accidental
release Relapsing Fever from Plum Island.
The original outbreak area was Plum Island:
http://www.actionlyme.org/PIIB.htm
and these spirochetes are not typical
for this kind of tick:
"Despite the intimate association of B. burgdorferi and I. scapularis,
the population structure, evolutionary history, and historical
biogeography of the pathogen are all contrary to its arthropod vector.
In the case of Lyme disease, movements of infected vertebrate hosts
may play a larger role in the contemporary expansion and
homogenization of the pathogen than the movement of tick vectors whose
populations continue to bear the historical signature of climate-
induced range shifts."
http://www.ncbi.nlm.nih.gov/pubmed/20394659


STEERE ADMITS LYME IS THE EXACT OPPOSITE OF
WHAT HE ALL ALONG SAID IT WAS, BECAUSE OF THE
REVELATIONS ABOUT WHAT PAM3CYS REALLY IS:
4) "Lyme" was never even close to being "just a
knee," as Allen Steere now admits:
http://www.ncbi.nlm.nih.gov/pubmed/20506317



NO "MD" IN AMERICA HAS YET SHOWN AN UNDERSTANDING
OF WHAT "SCIENTIFICALLY VALID" MEANS, TO DATE:
5) Unfortunately, Stupid-MD-America has not
one physician trained in actual science
to explain what the hell scientific evidence
means:
http://www.actionlyme.org/PRIMERSHELLGAME.htm
We can throw out all "evidence" of "Lyme disease"
outcomes - treatment or not - unless the OspA
gene was *not* used, but the REAL primers
*were.*

These SCIENTFICALLY CORRECT 16S and 23S RNA primers have
been used by the crooks since 1992 (even Allen Steere
determined that his funky strains were burgdoferi using
the correct RNA primers. (See for yourself:
http://www.actionlyme.org/STEERE_IN_EUROPE.htm )
but in treatment assays, Steere, et al, use the OspA
gene, knowing it mutates:
http://www.actionlyme.org/BRAIN_PERMANENT.htm
CDC officer Alan Barbour on antigenic variation
(mutation) of the OspA gene:
http://www.actionlyme.org/BARBOUR_MUTANTS_1992.htm
"DO NOT USE OspA FOR A VACCINE; IT WON'T
WORK DUE TO ANTIGENIC VARIATION," - CDC "officer"
Alan Barbour, owner of the ImmuLyme OspA patent:
http://www.actionlyme.org/CENTRAL_LYME_RICO_PATENTS.htm


And no MD explained to the FDA, either,
when LYMErix was removed, that LYMErix was not
a vaccine because Steere's Dearborn proposal was
never a scientifically valid test:
http://www.relapsingfever.org
per the FDA's idea of a scientifically valid
test:
http://www.labcompliance.com/info/links/methods/guidelines.aspx
http://www.labcompliance.de/documents/FDA/FDA-Others/Laboratory/f-507-bioanalytical-4252fnl.pdf

Here is a validation:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC270607/?tool=pubmed
In 1992 ^^^ Lou Magnarelli and Erol Fikrig
spiked *THE* *PATENTED* Borrelia-burgdorferi-
SPECIFIC recombinant region of flagellin to
increase the *LIMIT OF DETECTION,* or to make
this valid test MORE *SENSITIVE,*... or detect
more cases.

THAT ^^^ is how one performs and phrases
"SCIENTIFICALLY VALID."

This VALIDATED Bb-specific flagellin test was not
used to assess any vaccines outcomes, because everyone
knew OspA was never going to be a vaccine. The
recombinant portion of that Fla gene owned by Erol
Fikrig was never used in any treatment trial
assays and neither was the 16S or 23S RNA
used by Steere, Schoen, Wormser, et al,
whenever they wanted to find spirochetes in
*humans* since 1992, yet the number of copies
of the gene would be the same (same for
Fla as the RNA primers, *says Dr. Lee of
Milford Hospital*).


6) MDs ARE MORONS; THEIR VICTIMS SHOULD ALWAYS
GIVE THEM AN INTELLIGENCE TEST, FIRST, AND
NEVER PAY THE BILL UNLESS THE MD PASSES THE
TEST:
I propose that all of America start explaining
to their "MDs" what "science" and "medicine" mean
because to date, we still haven't seen one
single physician explain to anyone, much
less the USDOJ, that Lyme is a scientific
crime. The FDA referred me to their Disclaimer
page when I asked them about the "validation"
of the Dearborn case definition. They disclaimed
their obligation to actually look at the evidence
any BigPharma sends them:
http://www.actionlyme.org/FDA_DISCLAIMS_JOB_RESPONSIBILITY.htm

"I work for the ^^^gubbamint; no one *expects*
me to do my job because if I was smart enough
to know how to do my job, I would be working
for BigPharma!! :))), Thanks and have a nice day!"


It is ridiculous for this tard, below, to
assert that he knows what he is talking about
when the patients know far more about medicine -
not to mention science - than any MD has *ever*
demonstrated themselves to be.

No MD, *EVER*, has demonstrated that they
have a grasp on this laboratory crime; Allen
Steere now admits that Lyme is a disease of
immunosuppression, and Yale admits that Lyme
and LYMErix were the indirect cause of at least
one of the New Great Imitators, Lupus (activation
of Epstein-Barr; do not use an antibpdy test
because EBV is a TLR2 agonist, too:
http://www.actionlyme.org/LYMERIX_CANCEROLOGY.htm )

Despite the explosion of science, now, on
A) the mechanisms and the functional *reality*
of outcomes of TLR2 agonism
http://www.actionlyme.org/PAM3CYS_APPLICATIONS.htm ,
B) TLR2 and Staph Aureus or "Hospital-Acquired
LYMErix Disease":
http://www.ncbi.nlm.nih.gov/pubmed?term=tlr2[All%20Fields]%20AND%20%28%22staphylococcal%20infections%22[MeSH%20Terms]%20OR%20%28%22staphylococcal%22[All%20Fields]%20AND%20%22infections%22[All%20Fields]%29%20OR%20%22staphylococcal%20infections%22[All%20Fields]%20OR%20%22staph%22[All%20Fields]%29%20AND%20aureus[All%20Fields]&cmd=DetailsSearch
by fungal antigens, not a single MD in
America will acknowledge it or write about
it,... except where JAMA slammed the CDC, ...
after the WHO and the EU slammed IDSA,... over
fungal antigen-related immunosuppression and
the lies about LYMErix, and how that negatively
affected discovery in all (great imitator) diseases,
but especially in CANCER, tuberculosis and HIV - the
current global pandemics -,... after Anthony
Fauci, head of NIAID had to admit that he
had no idea what was doing, re the structure/
function of Pam3Cys-HIV-Tb... OspA:
http://www.actionlyme.org/Pam3Cys_Version15.htm


The next dang foo "MD" who dares to comment
is going to get the same "treatment" from me
until somebody finally tells the whole story
straight.


Kathleen M. Dickson
http://www.actionlyme.org
http://www.relapsingfever.org
========================================================

http://www.fosters.com/apps/pbcs.dll/article?AID=/20100606/GJOPINION_0102/706069933/-1/FOSOPINION

Lyme disease medical legislation is the right choice

By David Itkin, MD
Portsmouth
Sunday, June 6, 2010

My concern for legislating medical care, as proposed in HB 1326,
relative to immunity from Board of Medicine discipline for prescribing
long-term antibiotics for chronic Lyme disease, prompted me to write
this letter.

I am an infectious disease physician, who has been practicing in the
Seacoast area for 20 years and have seen and treated a large number of
patients with Lyme disease. I feel comfortable that the scientific
guidelines as advanced by my professional society, Infectious Diseases
Society of America and revalidated this past April, are medically
sound and simply "work" for the overwhelming majority of my patients.

That said, I recognize that there are rare patients who have chronic
multisystem complaints that are not helped with standard treatment for
Lyme disease. I have seen many of these patients through my career.
Not all medical symptoms fall into a clean diagnosis. Some have been
classified as having chronic fatigue syndrome, fibromyalgia, and
others. My observation is that some of these individuals seem to have
a true, undefinable medical condition that we are currently unable to
characterize. There are multiple symptoms including fatigue, muscle
pain, activity intolerance, sore throat, tender lymph nodes, disturbed
sleep and cognitive complaints. Over the years, many theories have
been advanced as to the cause of this disorder. Various viral,
bacterial and fungal etiologies have been advanced and refuted.
Testing on these patients sometimes demonstrates evidence of either
immunologic deficiency or activation, but not in a consistent fashion.
Clinical management of these patients is very difficult. In the
absence of a specific treatment, management is largely symptomatic.
The major portion of a visit to my office for a patient will involve
counseling and support. This takes a lot of time and energy on my
part. I sincerely wish that there was a "cure" for these patients. It
would be a lot easier for all involved to simply prescribe a pill than
to spend 45 minutes discussing lifestyle modification, stress
management and sleep hygiene.

"Chronic Lyme disease" fits this paradigm. In the absence of an easily
treatable and diagnosable disorder, the void has been filled with
inaccurate and self-fulfilling testing performed by non-validated
laboratories utilizing non-validated guidelines. This is not unique to
this illness. I have seen similar "loose" testing and treatment for
chronic fatigue syndrome patients. And from a patient's perspective, I
understand this. People are ill and are desperate to feel well again.
If a carrot is held out, who wouldn't want to grasp for it? It becomes
easy to cast those who offer the "cure" as heroes and traditional
practitioners as the villains.

Some patients will experience symptomatic improvement on long-term
antibiotics. There is a strong placebo effect which has been validated
in several scientifically-based, controlled studies. Furthermore,
there is a nonspecific anti-inflammatory effect of certain antibiotics
(including doxycycline) that can result in some modest symptomatic
improvement. Parenthetically, I have seen a number of patients with
serious adverse effects related to long-term antibiotics, who feel
afraid to discontinue them. I have had a number of patients that have
simply wanted me to validate that it was acceptable for them to come
off antibiotics.

The patient-doctor relationship should allow for an individualized
approach, for this or any illness. Often, after careful consideration
of all the risks and benefits, a practitioner will recommend a
specific course of treatment, even if it is outside of usual
conventions. Good physicians do this on a regular basis.

"Chronic Lyme disease" does not require specific dispensation as was
proposed in HB 1326 this year. Like any other medical illness, a
provider may decide to offer a treatment that diverges from the
accepted scientific guidelines. Even though the vast majority of
patients with Lyme disease are well-served with these guidelines, a
thoughtful medical evaluation may suggest a different approach. This
does not require a law. Opening Pandora's box with legislation puts
the government in the position of recognizing other chronic illnesses
without scientific validation.

Enacting a law to legitimize a medical condition sets a dangerous
legal precedent. Furthermore, such a law as proposed by HB 1326, may
actually do patients a disservice. Patients may be given a diagnosis
of chronic Lyme disease based on non-validated laboratory testing and
the weight of media and popular attention, at the expense of a true
and thoughtful medical evaluation. Appropriate medical diagnosis and
treatment may be delayed. This would be the price we pay for
displacing medical diagnosis and treatment from health care
professionals to legislators.

I again must emphasize that I have nothing but respect and compassion
for patients who are suffering with chronic illness. These patients
deserve the benefit of a thoughtful medical evaluation, not a cookie
cutter diagnosis and treatment. A compassionate provider may decide on
a case-by-case basis that a patient deserves a treatment that is
unconventional. A law is not needed for this. Good medical care should
be based on the specific application of evidence-based medicine on a
very personal level. These very personal medical decisions should be
left to providers, not to politics or public opinion.


"[Real] scientists are *fiercely* independent. That's the good
news."-- NIH's Top Fool, Anthony Fauci