Said The Fauc' to Lou Dobbs...
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Mort Zuckerman
Jul 18, 2008, 1:32:45 AM7/18/08
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Subject: Said The Fauc' to Lou Dobbs...
Date: Jul 18, 2008 1:29 AM
http://www.actionlyme.org/MKLEMPNER.htm
√ CHAPTER 1, WHAT IS SCIENTIFIC VALIDITY? We do have a
scientifically valid
test for Lyme antibodies.
√ CHAPTER 3, STEERE, in EUROPE, CREATES "CRYME DISEASE" rules out
validity of The Dreaded Klempner Report
√ CHAPTER 10, BIOMARKERS OF DISEASE - developed by the crooks, not
deployed
by Klempner
Klempner_DQB1_0602.htm = Full transcript of July 2001 South
Country RI
Non-Diseases of Summer Conference obtained while Mark Klempner should
have been
wearing a muzzle instead of a "bullet proof vest."
Lyme is due to Fibromyalgia, which is "Catastrophizing":
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=DetailsSearch&Term=11083273[uid]|
and, according to Mark Klempner, it is cured by "the placebo effect
of
antibiotics" and is prevented by the first ever vaccine against
catastrophizing,
LYMErix.
Why was Mark Klempner elevated to the head of a CDC Level IV
Bioweapons
lab in Boston after committing such outrageous lies about "chronic
Lyme?"
Hear it straight from the horse's mouth:
http://www.youtube.com/watch?v=yPn_T9qy4C0&mode=related&search=
Bioweapons? Secret haplotypes? Vaccinating people with
known agents
of immune-suppression? Not warning parents that these same haplotypes-
questions
might apply to their kids re forced vaccinations-with-no-
compensations?
Hmmm. The plot thickens...
Chapter 11 - Mark Klempner's bogus "long term" or "re-treatment"
"study"
I. The NEJM Klempner Report (no peer review)
II. "Bogus Articles" (a real and deliberate phenomenon, includes
"Negative
Data Rule" concepts)
III. Ceftriaxone Failure/Intracellularity
MarkKlempner_Fibroblasts.htm = 1992 Klempner proves
ceftriaxone does
not kill all borrelia due to intracellularity
IV. MMP-130 (the study shows Mark Klempner knows we're very sick)
Retro_Klempnerization.htm = 1997 Klempner's famous MMP-130
study.
Proves "objective signs"
V. Dys/Autoimmunity (HLA-DQB1*0602, OspA-induced immune
suppression, latent
viral, fungal)
VI. Points of Refutation of the Validity of the Klempner Report:
A) Dearborn was bogus; we don't know what kind of
patients Klempner
had
B) 2/3rds of the patients never had IV ceftriaxone
before; this was
a standard of care study
C) Klempner threw out DNA positive victims from the
start
D) Klempner never reported primers (we don't care if we
have Borrelia
outermongolii)
E) No scientifically valid assessments of outcomes of
this standard
of care "study" were used
VII. The NIAID Nutcase Anthony Fauci and his patented treatment
for immune
suppression diseases
I. The Dreaded Klempner Report: >> http://content.nejm.org/cgi/reprint/345/2/85.pdf
← In July 2001, the New England Journal of Do-Do publishes nonsense
because they
have no peer reviewers who are competent to science. That is, there
aren't any
peers; there aren't people either non-interest-conflicted or
competent to the
science and likely both, because as you will see, the NEJM is getting
sloppier and
sloppier. We can at this point expect that NOTHING is not ghost
written by the
Bigs.
Two controlled treatment trials of chronic Lyme....
New England Medical Center and Tufts University School of
Medicine, Boston,
MA, USA. klem...@bu.edu
BACKGROUND: It is controversial whether prolonged antibiotic
treatment is
effective for patients in whom symptoms persist after the recommended
antibiotic
treatment for acute Lyme disease. METHODS: We conducted two randomized
trials: one
in 78 patients who were seropositive for IgG antibodies to Borrelia
burgdorferi
at the time of enrollment and the other in 51 patients who were
seronegative. The
patients received either intravenous ceftriaxone, 2 g daily for 30
days, [THIS WAS
THE ARBITRARILY DEFINED STANDARD OF CARE AT THE TIME FOR THIS CNS
BACTERIAL INFECTION-
30 DAYS OF IV CEFTRIAXONE] followed by oral doxycycline, 200 mg daily
for 60 days,
or matching intravenous and oral placebos. Each patient had well-
documented, previously
treated Lyme disease but had persistent musculoskeletal pain,
neurocognitive symptoms,
or dysesthesia, often associated with fatigue. The primary outcome
measures were
improvement on the physical- and mental-health-component summary
scales of the Medical
Outcomes Study 36-item Short-Form General Health Survey (SF-36)--a
scale measuring
the health-related quality of life--on day 180 of the study. RESULTS:
After a planned
interim analysis, the data and safety monitoring board recommended
that the studies
be discontinued because data from the first 107 patients indicated
that it was highly
unlikely that a significant difference in treatment efficacy between
the groups
would be observed with the planned full enrollment of 260 patients.
Base-line assessments
documented severe impairment in the patients' health-related quality
of life.
In intention-to-treat analyses, there were no significant differences
in the outcomes
with prolonged antibiotic treatment as compared with placebo. Among
the seropositive
patients who were treated with antibiotics, there was improvement in
the score on
the physical-component summary scale of the SF-36, the mental-
component summary
scale, or both in 37 percent, no change in 29 percent, and worsening
in 34 percent;
among seropositive patients receiving placebo, there was improvement
in 40 percent,
no change in 26 percent, and worsening in 34 percent (P=0.96 for the
comparison
between treatment groups). The results were similar for the
seronegative patients.
CONCLUSIONS: There is considerable impairment of health-related
quality of life
among patients with persistent symptoms despite previous antibiotic
treatment for
acute Lyme disease. However, in these two trials, treatment with
intravenous and
oral antibiotics for 90 days did not improve symptoms more than
placebo.
Unaware, perhaps, is the NEJM that Mark Klempner had previously
reported (1992)
that ceftriaxone failed to kill all the spirochetes due to
intracellularity and
unaware, perhaps, is the NEJM that Allen Steere published twice that
treatment fails
to eradicate all borrelial even after multiple courses of treatment in
about a third
of the cases... in the NEJM. You could call this stupidity, or, you
could call
it stupidity on the part of the NEJM, but I call it plain old
stupidity because
no matter how you look at it, the New England Journal is totally
incompetent.
You know, I don't know what's holding them back - the
Massachusetts
Medical Society could make a lot more money if they simply promoted
themselves as
an advertising agency.
II. BOGUS ARTICLES:
The first thing to know about Mark Klempner is that such a thing
as writing
"bogus articles" is well-established.
First known bogus article:
1992, Fikrig, as regards OspA vaccinations disinfecting ticks
using immunofluorescing
antibodies against stuff not expected to be there or washed away:
http://www.pnas.org/cgi/reprint/89/12/5418
As we know from Chapter 1, Fikrig had a scientifically valid
DNA method
to detect burgdorferi or even any of the other spirochetes, since this
is what his
Flagellin patent, US 5,618,533, is all about and the report associated
with the
patent was published in 1991. 1991 is before 1992 (this is a science
or math fact
that should be obvious, except for the part where we have people given
MD degrees
in America who clearly can't make this mental leap). Why didn't Fikrig
use
a DNA method to determine whether or not vaccination of mammals
disinfected the
ticks who later sucked on them?
Second bogus article(s):
Dressler/Steere with the funky strains in Europe (Chapter 3)
to come up
with the Dearborn standard testing schema. There is no such thing as
"receiver
operating characteristic" in the FDA's criteria for a valid
bioanalytical
method. The CDC's current, published diagnostic schema and standard is
a bogus
article. The ELISA misses all the neurologic cases in the first step.
Any treatment
outcomes where this bogus case definition of the disease was deployed
can be thrown
out as scientific garbage, as is the case with this 2001 Klempner
"study."
OspA gene bogus articles:
All treatment outcome articles where OspA primers were used
are bogus because
all these antigens undergo antigenic variation and we should be
looking for all
borrelia - not just burgdorferi - by using specific flagellin and
specific intragenic
spacer RNA. The Mouse Infectivity Test is the ultimate test because
of the difficulty
in reculturing spheroplasts without actual blood cells in the media
which are spirochete's
real food. People don't care which kind of Borrelia they have. They
don't
care if they have Lyme or Relapsing Fever as long as they're not
diagnosed as
DSM IV/ICD-9 Viagra Deficit Syndrome (VDS), Hyposexifemzalgiarrhenus
or Negapenia.
Over this "OspA is Lyme" business, the Czech Republic called Americans
stupid and incomprehensible.
Previous chapters reveal that we know how to perform
scientifically valid
tests for both identification of the disease itself (yet to come,
cysts and the
MIT or Mouse Infectivity Test), and markers or signs of illness,
meaning we have
no use for psychiatrists in the area of chronic illnesses.
All hospitals should have their own labs and equipment and
samples do not
need to be sent out to labs, because we have no use for insensitive,
invalid, "test
kits." Some labs, like Quest, even charge for test kits used in their
labs
and then have the audacity to disclaim that test kit test, and refer
you to another
lab for the real result. In other words, you may not know it until
you read your
own lab results, but you may be paying a lab to run a fake test kit
test, they'll
charge your insurance company or Uncle Sam for that test, but then
they literally
disclaim the results and literally refer you elsewhere to get a real
test for that
marker, and no one does a thing about it. It happens to be fraudulent
to be charging
someone for an invalid test, because not only is the result invalid,
time is lost,
and you have to pay for that test again. I have proof of this, which
is why I am
naming names: QUEST Labs.
So, we know how to run scientifically sound tests on people to see
in what way
they are sick. We can perform radioimaging (SPECT, MRI), tests, and
we can use
specific antibody tests, expanded antibody tests (antiphospholipids,
antigangliosides,
anti-heat-shock proteins), and we can look for dysregulated cytokines
in the blood.
We can look for immune complexes in the blood. We can perform spinal
fluid analyses
to look for gliosis (destruction of glial cells), cytokines
dysregulated monoamines
and we can do electromyography. We can look for matrix-
metalloproteinases that
should not be there and quinolinic acid in the cerebrospinal fluid (a
marker of
infection). We can perform DNA and RNA tests to look for viruses and
bacteria.
We can look at cells to see if they are aberrant-looking, etc. We can
perform a
whole slew of tests on people to see if they're sick.
Enter Mark Klempner;
WHEREUPON, scientifically valid testing is never done, even to the
tune of 4.7
million dollar grants to a guy who found out the reason ceftriaxone
failed to cure
people was probably due to the intracellular spirochetes. Mark
Klempner also happens
to be the guy who found a specific marker of Lyme bacterial
infiltration into the
central nervous system and said he found this specific MMP-130 marker
in no other
diseases of the central nervous system.
And then he said we have no disease at all for that 4.7 million
dollar grant.
And then he was promoted to the head of a CDC bioweapons level IV
lab in Boston.
So, is Mark Klempner and the Lyme/LYMErix fiasco a result of the
Bigs (Insurance
and Pharma) in concert with the lying patent profiteers of the CDC or
is this a
bioweaponeering bumbler situation (cover-up of an accidental release
from Plum Island),
or is it both? Or is it yet a third condition to be suspected as a
result of the
libelous "NAZI" and other bizarre accusations and statements by the
Israeli
Durland Fish?
Is this fraud due to CDC personal biopatent weaponeering or
BigInsurance interfering
or is a third party entitled to the information that we paid for but
are not allowed
to have? We know it is true from Sibel Edmonds and the State
Department's Marc
Grossman that Israelis are here in the USA infiltrating the
universities and nuclear
facilities to steal intelligence (bio and nuclear) despite their self-
allegation
of being the intellectual elite (why do they have to steal information
if they're
all brilliant?). We have seen the Israeli Durland Fish flatter the
would-be NIH
"scientist" Edward McSweegan to get McSweegan to perform the dirty
work
for Fish, such that Fish could trash the Lyme Disease Foundation's
Karen Forschner
because of Karen's discoveries that refute the nonsense the ALDF.com,
Yale and
CDC cabal spew. We know who the ALDF's financial backers are (e.g.,
Mortimer
Zuckerman, the AIG Greenbergs, etc.). The FBI is not interested in
protecting us
from corporate crime because their focus is porn, unaware are they
that they are
perceived as, in the words of Henry Kissinger, "dumb, stupid animals
to be
used as pawns for political purposes." The New Haven, Connecticut,
FBI cannot
even be insulted into reality, confirming the "dumb, stupid animals"
allegation.
The evidence is that the crooks want to promote another OspA
(trivalent, Baxter)
vaccine, but we think that's a cover for the first crime, which was to
claim
there was no neurologic Lyme disease. This lie was invented to falsely
state that
there was no neurologic disease outcome as a result of vaccine failure
or the immune
suppression results (which we think are the same thing) of OspA
vaccination.
In a complaint to the Israeli Michael Chertoff in August 2005, it
was reported
that:
27) Martin J. Mattessich President & CEO, Director
"Prior to
becoming President and CEO of Agilix, from 1996 to 1999 Mr. Mattessich
was the co-founder
of two Yale University-sponsored biotechnology companies, L2
Diagnostics, LLC (diagnostic
serology) and polyGenomics, Inc. (gene discovery for polygenic
diseases) , and a
consultant to CuraGen Corporation, a publicly held genomics company
(pharmaceutical
drug ...."
With the blood he intended to get from the L2 Diagnostics-
Imugen nationwide
monopoly on testing, they can identify new diseases to commercialize.
We Americans are pretty stupid people, huh? When will we get it
that the "government"
is not set up to serve the interests of the people? How many times do
we have to
be smacked upside the head before we realize that the only thing we
can do is request
that other nations kidnap and torture our biowarfare criminals like
CDC officers
and several members of the NIH?
III. Bearing in mind that ceftriaxone is a meningitis drug - a
clue to the fact
that Lyme is a brain disease and not a knee disease - Mark Klempner,
in 1992, found
that the reason ceftriaxone did not kill all the Lyme spirochetes was
that they
were intracellular. Intracellularly, these spirochetes are protected
from the toxic
effects of antibiotics. Alan Barbour reported that in the presence of
antibiotics,
these spirochetes reverts to the cyst or spheroplast form, which we
all know to
not be the end stage but rather a dormant or self-protection stage.
The intracellularity
of spirochetes has been well-known for a hundred years. Intracellular
spheroplast
dormancy is what characterizes these permanent spirochetal
infections. Klempner
went with this stupid 4.7 million dollar study anyway, knowing the
reason ceftriaxone
failed. We can tell from his conclusions that this "study" was
conducted
because that he/they intended not to allow us to be treated with
ceftriaxone regardless
of the truth.
IV. The second most important study published by Mark Klempner was
the matrix-metalloproteinase
study where he found that 78% of neuroborreliosis patients had MMP-130
in their
spinal fluid, and he found that to be a SPECIFIC marker. That is, he
did not find
this particular nerve and brain degrading enzyme in people with other
neurological
disorders.
This is a pretty amazing report because Klempner later said there
was no evidence
that Lyme causes cognitive impairment, when his argument for studying
MMP-130 was
because of the cognitive impairment in Lyme.
If the Lyme criminals claim "chronic bad-knee-Lyme" is an
autoimmune
disease due to the hyperbinding of OspA to Steere's haplotypes, then
why shouldn't
people imagine believe there isn't either a binding or a non-binding
autoimmune
phenomenon going on in neurologic Lyme instead of saying such a thing
does not exist?
But, we're not saying chronic neurologic Lyme is strictly an
autoimmune
disease, like Steere is saying (fraudulently) that his kind of chronic
Lyme is an
autoimmune disease. We're saying, A) there is more than one mechanism
of autoimmunity
or immune dysregulation, so there does not have to be an either
binding or non-binding
phenomenon going on; there could be other mechanisms [errant cloning
of either B
cells or T cells (pseudolymphoma), immune suppression due to tolerance
and down-regulation
of HLA, disturbed pathways of either HLAs or TLRs, disturbed signals
from disturbed
cytokine production, cytokines acting as neurotransmitters, antibodies
acting as
neurotransmitters, etc.,...]; and B) persisting infection is not
independent of
autoimmunity, no matter what kind of autoimmunity. It's not either/
or. Chronic
borreliosis is definitely persisting infection, but it also could be
autoimmune
neurologic disease. It is likeliest immune dysregulation process sets
in combination
with persisting infection. The immune suppression outcomes of
tolerization to shed
borrelial antigens renders people susceptible to opportunistic
infections and the
exacerbation of latent viral and other infections of all kinds which
could be the
cause of the New Great Imitator outcomes. The immune suppression's
resultant
exacerbation of viral and bacterial or mycoplasmal infections of all
kinds could
be the secondary causes of autoimmunity. The possible mechanisms of
illness are
infinite. Instead of trying to discover why people are sick for the
benefit of
revealing that information to others, this information is being kept
private by
the cabal.
As we have seen in the chapter on BIOMARKERS, the suppression of
the science,
here, on immune suppression outcomes of Lyme Disease and LYMErix, has
negatively
affected all other chronic and fatal diseases. Their crimes are not
just against
people bitten by ticks.
QUI TAM and RICO- Recover the money (temporarily suspend the
reality where
the government no longer is about protecting the people):
One way to to stop the tsunami of bovine excrement from the Steere-
CDC camp
is to force them to retract all of their "bogus articles" and start
over,
particularly with the moneys recovered by those who profited- and
attempted to profit
from- this spin, like the insurance companies. So far, the Lyme
crooks have not
profited in the way they intended since LYMErix was withdrawn,
trashing their intended
monopoly on testing. But they have taken fraudulent income from the
government,
so the individual prosecutions of the Lyme perps will come as
separate, individual
Qui Tam fraud cases. The crooks made false claims to the government
in order to
get more funding to spin out more nonsense tales, like Klempner's 2001
"repeat
treatment," "study." Whenever they applied for a grant on the basis
of Dearborn being a reality, that is a false claim for grant money.
They clearly
also made false claims on behalf of BigInsurance, since Kaiser bailed
out the financially
failing New York Medical College and they're still there at New York
Medical
College, training MDs. That happened at the same time as the
establishment of the
ALDF.com which was right after the 1989 IDSA Review of Infectious
Diseases. special
publication about how serious Lyme was and that the treatment endpoint
was unknown.
As stated in the introduction:
The Lyme crymes and the cabal - The 180s - are about an
intended monopoly
on vector borne diseases "test kits" and "vaccines" and could
not have happened without the Bayh-Dole Act. The monopoly involved
Kaiser-Permanente
(still) at New York Medical College and the deal was:
No one is allowed to have any illness signs nor is
treatment to be paid
for, until the alleged "vaccine" is ready, and then everyone will be
notified
about how serious that particular vector borne disease is, and that
they better
get the "vaccine."
This appears to be the agreement between the biotech patent
profiteers and
Kaiser-Permanente at New York Medical College, which was in financial
trouble in
1990 under the leadership of John J. Connolly, leading to the
establishment of the
false front non-profit called the American Lyme Disease Foundation
Recall that
when charging a RICO, one does not have to prove the parties sat down
together and
made deliberate statements and signed agreements about their intended
crime. There
merely has to be the appearance that there was an agreement.
http://www4.law.cornell.edu/uscode/18/1961.html
(4) "enterprise" includes any individual, partnership,
corporation,
association, or other legal entity, and any union or group of
individuals associated
in fact although not a legal entity;
This we can prove due to the abundant statements made by the
ALDF.com cabal
about how serious and dangerous Lyme Disease is when they wanted to
sell their bogus
vaccine:
"It is well known that Borrelia burgdorferi indeed after
asymptomatic
infection can lurk or secrete itself in certain areas of the body,
perhaps the central
nervous system or perhaps the joint spaces, only to reappear months or
maybe years
later in the form of late stages of illness which are harder to
diagnosis and treat.
"It is probably worth noting, since I have learned a lot, that
we don't
have the clinical luxury in private practice that we had in the
SmithKline Beecham
trial in which we had baseline sera on all the patients who enrolled
so that when
they presented with symptoms, we could draw acute and convalescent
serologies [recall
that that was the old diagnostic standard- see Chp 3] so as to compare
them with
each other and with baseline to better understand what symptoms they
are presenting
with.
Finally, there are indeed many dilemmas in therapy. In
particular, untreated
or inadequately treated Lyme disease may lead to the chronic morbidity
with which
we are very familiar. Most commonly arthritis and the not common but
complex neurological
syndromes are what often result and which confront the primary care
physician in
the office diagnostically and therapeutically.
These particular outcomes result in much more intensive, long-
term expensive
therapy, often in the form of long-term intravenous antibiotics.
These are the
patients who often are refractory to treatment. Indeed, these are the
patients
in whom symptoms seem to persist despite what we have given in terms
of adequate
antibiotic therapy by any known measure.
In conclusion, we need a vaccine for Lyme disease because it
is increasing
in incidence and geographic spread. We need a vaccine for Lyme
disease because
there are problems in clinical diagnosis, its laboratory evaluation,
and its treatment.
We need a vaccine for Lyme disease because preventive measures are
unfortunately
ineffective. Lyme disease is indeed vaccine preventable.
Availability of this
vaccine would lead to a significant reduction in chronic sequelae and
substantive
morbidity. Lyme vaccine is thus a critical new public health approach
to the primary
prevention of Lyme disease in the United States. Thank you very
much."--
Vijay Sikand, EAST LYME, CT to the FDA Vaccine Committee in 1998
All in all, the original USDOJ July 2003 claim of "scientific
fraud and
racketeering" was correct. I researched the crime and the laws
thoroughly
before filing the RICO complaint with the USDOJ.
It was FRAUDULENT for Mark Klempner to use a check list to assess
patient outcomes
when he knows there is a very specific marker in the CSF for damage,
and a rational
person would wonder if the presence of this nerve degrading enzyme was
diminished
with a month of ceftriaxone treatment. 'Not to mention utterly crazy
to try
to sell a vaccine for a disease over which Mark Klempner was at that
very moment
(Klempner's study started in 1997) engaging in a bogus protocol
intended to
prove Lyme disease- that terribly morbid chronic condition over which
Vijay Sikand
begged the FDA Vaccine Committee to approve LYMErix - does not exist.
There is no question, thanks to Mark Klempner, that we can validly
claim that
LYMErix was a placebo vaccine against Lyme hysteria. It was the
world's first
ever placebo vaccine and one that Yale said everyone in the country
would need
every year. LYMErix was the first ever vaccine against
catastrophizing.
And no one in the Connecticut, New York or Massachusetts
boards of health
or medical boards said a word. They STILL haven't said a word about
this placebo
vaccine against hypochondria...
And the funny thing is, this cabal intends to repeat the exact
same ridiculous
proposal:
Journal home > Archive > Correspondence > Full Text
Correspondence
Nature 440, 278 (16 March 2006) | doi:10.1038/440278b
Lyme vaccine demonized by advocacy groups
Edward McSweegan1
1. 1692 Barrister Court, Crofton, Maryland 21114, USA
Sir:
As a microbiologist who managed a federal programme on Lyme
disease in the
1990s, I consider that any new clinical trials of a vaccine candidate
based on the
protein OspA, as mentioned in your News Feature "Uphill
struggle" (Nature
439, 524-525; 2006), should be confined to Europe, for three reasons.
First, Lyme disease is non-communicable, readily treatable
with common antibiotics
and geographically localized in the United States. Neurological cases
-- where treatment
can be problematic -- are more common in Europe and a new vaccine may
reduce the
costs and consequences of infection.
Second, European experience with the widely used tick-borne
encephalitis
virus (TBEV) vaccine may facilitate vaccine-trial recruitment and
greater public
acceptance of a new Lyme vaccine.
Third, Europe is a less litigious environment and is largely
free of organized
Lyme-patient advocacy groups. In the United States, activists have
turned Lyme disease
into everyone's backyard bogeyman. They have demonized experts for
their views
on treatment and prevention, and hired lawyers to successfully argue
the dangers
of vaccine-induced autoimmunity (Philadelphia Inquirer B03, July 9
2003).
The activists are already using Internet discussion groups to
warn against
a new vaccine. One of them recently wrote "I would encourage all Lyme
patients
to consider writing letters, emphasizing the lack of demand for the
last vaccine,
and also the fact that any future vaccines can expect a lack of
cooperation, protests,
legal quagmires, etc."
A careful, hysteria-free trial of the new OspA vaccine
[remember now, OspA
is a placebo vaccine against hysteria] in Europe may help to undermine
the opposition
to it in the United States.
You'd really have to be a world class jackass to propose that Lyme
is not
dangerous while at the same time saying Lyme is so dangerous that we
need a vaccine
against it. Here McSweegan says he needs a hysteria-free trial of a
new OspA vaccine
-- which Mark Klempner says is a placebo vaccine against hysteria
because, Klempner
said, Lyme is a non-disease cured by "the placebo effect of
antibiotics."
We have never seen a more insane set of American scientists
continually get their
insanity published.
And, ahem, I add that LYMErix, I said (TO THE FDA VACCINE
COMMITTEE in JANUARY,
2001), caused an immune dysregulation syndrome and not autoimmunity:
http://www.fda.gov/ohrms/dockets/ac/01/slides/3680s2_11.pdf
Ya see, because I am a real scientist, which means I have no
preconceived ideas
about data. I let the data tell me what to do, and not the other way
around. I
am not a man and do not get all jerked off and whack my pee-pee on my
time off (nor
post penis data on the Lyme newsgroup, like Yale's Durland Fish), nor
do I pretend
the whole world happens because of sex or me or my pee-pee. If
anything, the absence
of a penis is a godsend, because we women can think so much more
clearly than any
of these self-alleged scientists or MDs. Clearly Mr. Peanut is a
major distraction
even in the world of vaccines. Yale's Steven Malawista literally
declared that
the brain should be thrown out because it is "a complicating
variable."
He really got that insanity published in a journal:
"I have largely limited the discussion here to Lyme arthritis,
the
simplest case because the end point (no more arthritis) is so clear,
and one does
not have to introduce complicating variables such as the blood-brain
barrier."
--- Stephen Malawista, Yale University
I wonder if castration would help in more of the DSM disorders
than the sex-OCD
so common to psychiatrists? Clearly McSweegan, Klempner and Malawista
are out of
their minds, but remain free and unmedicated. They remain free and on
the loose;
free to publish scientific insanity that is "dangerous and harmful to
others"
in the medical journals. I have said many times that Dante's Inferno
needs
to be updated to include a new circle of hell for people who try to
pass off such
utterly crazy shit as medicine.
Yale is the anus mundi.
V. Dysimmunity and the Other Secret Multiple Sclerosis Haplotype
(HLA-DQB1*0602)
The following is the transcript of what Mark Klempner secretly
told the attendees
of the Non-Diseases of Summer Conference at South County Hospital in
Rhode Island
on approximately July 21, 2001 (it remains a secret, but blows away
all of Klempner's
conclusions):
"And, that is, that when you look for the possibility of an
autoimmune
disease, the best way to look is to see if there is any genetic
clustering in HLA
haplotypes. The reason for that is the way antigens get presented in
the context
of who you are, that is, your HLA haplotype. And we can talk in some
detail about
that. Those diseases that I think everybody would agree are so called
Autoimmune
:lupus, rheumatoid arthritis, type 1 diabetes, and perhaps MS, have
some clear genetic
clustering that leads us to believe that these are indeed autoimmune
diseases, although
we do not satisfy so-called Koch's Postulates of autoimmune disease
that we've written[?-KMD]
about. And the odds ratio for your having that particular HLA type,
in the case
of R.A, a DR4, or a DQB0602 to protect you from type 1 diabetes, are
on the order
of 3 to 6. One of the ones that is probably highest, of course, is
B27, in patients
with alkyloiding spondolytis and the like. It turns out that if you
look at the
first 51 patients with post-treatment chronic Lyme disease, the
patient population
that participated in our study, there was a very high incidence of
DQB0602 with
an odds ratio of 770%. So it may well be that exposure to THAT
organism with THAT
background of HLA haplotype may lead you to develop chronic symptoms.
That is a
hypothesis that needs to be tested. It would obviously lead to an
entirely new
form and approach to therapy. "
http://www.youtube.com/watch?v=yPn_T9qy4C0&mode=related&search=
Hear this very big secret not for large dissemination straight
from the horse's
mouth. There were no questions by the MD-crowd at Rhode Island's
South County
Hospital about this HLA secret. None of the physicians questioned
it. They just
all pretended to understand what Mark Klempner was talking about. I
think pretending
to know what a medical scientist is talking about when you are an MD
is a mental
disorder that should be added to the DSM-V.
Like, there was no mystery to these Rhode Island MD morons when
Mark Klempner
said there was no disease at all, but that he discovered this
autoimmune neurologic
haplotype that they're supposed to "not largely disseminate found at
an
8 times higher rate than would be expected due to chance in all these
fricking Yuppie
disease-wannabee whiners who would otherwise have nothing to talk
about cocktail
parties and Fibromyalgia is a women's disease related to the boredom
associated
with low innate intelligence and a frustrated desire to be a soap
opera star."
Not a one of them said, "SO YOU FOUND SOMETHING WRONG WITH THESE
PEOPLE,
DR. KLEMPNER???" They instead swooned and kissed his butt and asked
if he
was a victim of us crazy Lyme victim terrorists. They fed this
bastard's ego
instead of having a single independent thought among the fifty or
hundred or so
of them. Rhode Island is a very, very stupid and backward place.
'Even stupider
than southeastern Connecticut if that were possible.
In a follow up study published in 2005, Klempner and Wormser
reported that there
is no association between haplotypes and Chronic Lyme:
http://www.journals.uchicago.edu/doi/pdf/10.1086/432733
In this report they say that the chronic-knee people generally
feel well, except
for their arthritis symptoms. This we suspected just from our limited
experience
with such rare victims, and also due to a statement from Vijay Sikand
at the 1998
LYMErix vaccine meeting where Sikand states that these arthritis
people could be
considered "immune competent," or are able to make enough antibodies
to
fight off infection. They say that this is a blinded study and that:
First, we suspect that this is untrue in that these criminals play
a primers
shell game, as previously mentioned. Secondly, this supports the
notion that it
is the immune suppression-exacerbation of latent common infections
(Epstein-Barr,
Mycoplasma in the blood, Cytomegalovirus, etc.) caused by chronic Lyme
Disease and
LYMErix vaccination, due to the tolerization of fungal antigens
(downregulation
of HLA molecules) and the inhibition of the auto-kill kinase mechanism
induced by
OspA as discussed in the Biomarkers chapter (10).
Mark Klempner reported that OspA could cause cross reacting T
cells to neurologic
tissues. He reported in 1998 that:
"T cells that react to OspA, OspC, and p22 epitopes also
recognize
MOBP, SST-R1, and IL-R1, respectively, on neurons, possibly leading to
encephalopathy
and radiculopathy. T cell recognition of synovial and neuronal
proteins can cause
chronic symptoms for years after the initial infection. It is not
known whether
the spirochete is still present during this chronic stage, or whether
symptoms are
strictly due to T cell autoimmunity."
Klempner says here that OspA (either from the bug or from
vaccination) could
cause an autoimmune disease of the nervous system. This possibility
(not fact)
was never mentioned in his "chronic Lyme" "study," yet clearly
this report was published in 1998, when Klempner's "chronic Lyme"
"study" was ongoing and clearly no new evidence emerged on persistence
of the infection. Klempner also reported in 2003 with a University of
Connecticut
"ass ociate" (Kaplan) that there was no such thing as cognitive
impairment
associated with "Lyme Disease."
We agree that that's a no-brainer, since there is no such thing as
"Lyme
Disease." "Lyme Disease" is an imaginary self-limiting arthritis
in a knee that needs no antibiotic treatment, but it does apparently
need a bogus
vaccine.
Klempner never reported this information about OspA vaccination
possibly being
the cause of an autoimmune brain disease to the FDA nor said something
about it
after the FDA approved LYMErix. They guy is the ultimate low-life.
All of this data, including a complete dub, a tape, of this July
2001 Klempner
lecture in Rhode Island along with a transcript, was given to the US
Attorney in
Connecticut who did nothing about it and then was promoted twice in
the USDOJ.
CT Attorney General Richard Blumenthal and his staff then had to take
over the US
Attorney's job for him without the federal pay and the DOJ resources.
After committing the crimes of LYMErix and this fake long term or
repeat treatment
"study," Klempner was promoted to the head of a CDC Level IV
bioweapons
lab in Boston. This should be seen as a criminal endorsement, such as
US Attorney
Kevin O'Connor of the District of Connecticut being promoted to
Alberto Gonzales'
Chief of Staff, and then when Gonzales went down, O'Connor was given
the Number
Three position at the United States Department of Justice (sic).
Crooks in government are promoted and whistleblowers get the bag
job, since
we're talking Republican whores, here, which is the only kind of
Republicans.
Is the US not about to undergo a bigger financial collapse than the
Great Depression?
Who outsourced us? Who sold out our rights to the corporations?
About the likes of even the local whores, like Cathy Cook (R-
Mystic, CT) and
Rob Simmons, former Republican Congressman from Stonington,
Corrupticut, we say
"We grows da hoes big around he-yuh,... since Pfizer is nearby and we
use almost
literally use Viagra as fertilizer ta grow duh Republican hoes."
Repeat after me, class:
1) Klempner found that spirochetes are intracellular and resistant
to ceftriaxone.
2) Klempner found that Lyme is a chronic infection that causes
degradation of
the central nervous system.
3) The haplotypes data was not reported in Klempner's Long term
treatment
report but a subsequent article by Wormser and Klempner indicate an
increasing likelihood
that Chronic Neurologic Lyme is the New Great Imitator due to the
immune suppression-related
exacerbation of latent viral and acquired fungal infections of all
kinds, rather
than neurologic autoimmunity. Given the fact that OspA is the source
of the immune
suppression, that alone could be the cause of the cover up
(vaccination with OspA
and the cover up of the damages- the New Great Imitator outcomes of
LYMErix). While
we once thought there must be some association with Multiple Sclerosis
haplotypes
allegedly secretly found in chronic neurologic Lyme and the tolerance
to Pam3Cys-related
downregulation of the antigen-presenting cells (and the subsequent
cessation of
antibodies to these antigens or the person becomes "seronegative"), it
now appears there was no association. It could happen to anyone.
We knew about the immune dysregulation in 1992 from the NIH's, the
NCI's
and the US Army's Paul Duray when he revealed the mutated lymphocytes
and stated
that these looked like Epstein-Barr transformed cells. None of this
was pursued
because scientific discovery could interfere with the intended
propaganda or marketing
of LYMErix.
4) Mark Klempner suggested in 1998 that LYMErix could be causing
an autoimmune
neurologic disease but did not report this to the public, ever, as a
reason for
concern or a reason to withdraw LYMErix.
5) Klempner was promoted by the CDC to the head of a CDC Level IV
bioweapons
lab for his outrageous lies to and about the public.
=======================================
VI. The following facts refute the validity of the Klempner "long
term"
treatment "study," published in the New England Journal of Malarkey on
July 12, 2001:
A) The CDC positive "case definition" has never been proven to be
accurate or valid for late, treated Lyme, which were the patients
Klempner claimed
to be "studying." It was never proven to be a valid method to detect
Lyme in the first place. No one knows what, exactly, the Dearborn
case "definition"
criteria means, since no one agreed with the Steere IgG proposal at
the 1994 CDC
Dearborn, MI, self-alleged conference, self-alleged to be about
"Standardization
of Western Blotting." Steere never validated his IgG Dressler/Steere
method
according to the FDA rules for the validation of an bioanalytical
method. The participants
in the Dearborn conference said Steere's IgG proposal was 8-28%
accurate when
tested in the field.
When Steere tested his own proposal in the field, he found that 39
of 54 arthritis
patients were positive to his IgG panel proposal of 18, 23 (OspA), 28
(porin), 30,
39 (flagellar sheath), 41 (flagellin), 45 (porin), 58, 66 (porin), 93
(Could be
31 times three, or it could be the specific brain invasion antigen
that the Europeans
claim). We actually have no idea what Steere observed, since he
obtained this "data"
with bogus, NIH- and CDC- NOT-recommended strains from Guilford, CT,
Germany and
Russia, and to boot, they were all "HIGH PASSAGE" (strains FRG and
high
passage G39/40). Since we don't know what "Dearborn positive" means
in previously treated patients, we have no idea what kind of patients
Mark Klempner
had. Even the participants of the CDC's bogus Dearborn conference,
(Phil Molloy)
said ~ "We have no idea what Dearborn means." Therefore, the only
real
result Mark Klempner had from this "study," was that 78 out of 1800
patients
tested Dearborn positive after some antibiotic treatment (accuracy of
Dearborn Lyme
is 4% in treated patients).
B) Klempner's "study" was supposed to be a "repeat treatment"
"study" of previously treated Lyme victims, when most (2/3rds) had
never
had previous IV ceftriaxone treatment. He already knew the reason
ceftriaxone failed
to cure. At the time of the proposal of the Klempner study protocol,
the standard
of care was 30 days of intravenous ceftriaxone- which was an arbitrary
determination
in the first place. The standard of care was 30 days of intravenous
antibiotics
at the time of the Klempner "study," since that's the standard mode
of delivery of antibiotics for brain infections or meningitis and was
in use for
years.
Thus, Klempner's "long term re-treatment study," was a "standard
of care study," and it showed that 30 days of the IV drug used for
bacterial
infections of the brain or meningitis was not enough intravenous
antibiotics and
that the chronically fatigued, neurologically and cognitively impaired
victims of
Klempner and Lyme should have been given at least 2 months of
ceftriaxone.
It was always known that borrelioses are permanent brain
infections and Relapsing
Fever. Therefore we would expect that Lyme should be treated as a
Relapsing Fever
brain infection, and that the treatment of its victims should be
relapsing IV ceftriaxone.
No one says these things because they are logical. What we know now
from the Fallon
study is that one should start with at least 3.5 months of intravenous
ceftriaxone
and if patients relapse after that, perhaps add another month. And if
they relapse
after that, repeat. Somewhere along the line it became acceptable to
tell people
it's okay if they remain chronically miserable, when the same people
know of
a treatment that brought relief (Dattwyler 12821734). Amazingly,
these bizarro
facts have never, ever once made it into any media, much less main
stream media.
The MDs don't ask any questions and the newspapers have forgotten the
part about
investigating unanswered questions. The media and the AMA and the DOJ
totally accept
hypocrisy to the point where they're convinced they're the guardians
of
the corporations rather than the people. I feel like I'm watching that
black
kid in Florida DCF pediatric prison being beaten to death by several
prison guards
for being a juvenile thug on a national scale. This country is so
screwed up and
the victims are so routinely tortured and we're so used to it, that
the next
thing we can expect is a new wave of New Roman Coliseum Theatres
moving back into
the towns with the lions and the blood and guts and gore as a new way
to treat sick
people... and then we'd have to listen to the animal rights people
crusading
over the poor lions' diet.
C) Klempner threw out PCR positive patients and then lied about
it. Klempner
reported that no PCR-positive patients were included in his study. He
stated right
in the full text NEJM article that he did not accept PCR positive
victims in his
study. There were PCR positive Klempner victims who were excluded from
the "study"
because they were positive and this is known to the Lyme community
since these rejectees
are part of the Chronic Lyme community. In the audiotape of Mark
Klempner at the
South County Non-Diseases of Summer Conference in July 2001, Klempner
said that
out of 2000 patients, none were DNA positive for the Bb DNA in their
spinal fluid.
Klempner is a liar.
D) Mark Klempner never published what primers he used to determine
"DNA
negative" in the spinal fluid of his victims. As we have seen in
previous
chapters, one must use genus-specific primers such as multiple
Borrelial (from several
of the genera) flagellins and intragenic spacers (RNA) that identify
Relapsing Fevers
(or Borreliae). Klempner claims to have used a culture method when we
all know
and knew culture is inferior to DNA/RNA testing or the Mouse
Infectivity Test.
When asked directly to reveal what primers he used, Mark Klempner
refused to reply.
According to IDSA's Russell Johnson, it "could take months" to recover
intact spirochetes from the spheroplast form in BSK media. Klempner
only attempted
to reculture spheroplasts from spinal fluid for 3 weeks.
E) No Scientifically Valid Tests Used to Assess Outcomes, and then
he claimed
hysteria to be the cause of the illness. Klempner even claimed that
people who
got better from treatment were reporting merely "a placebo response to
antibiotics."
The Fibromyalgia Impact Questionaire (FIQ) was invalidated rather
than validated
for use in Lyme victims. Arthur Weinstein has proposed method
validations in the
past which are not validations. In the case of the FIQ, he found that
Fibromyalgia
and Lyme disease were two different diseases. If they are two
different diseases,
the test or the method itself is not valid, since a validation
requires that the
test is SPECIFIC to the analyte in question.
The second most glaringly ridiculous aspect of the Klempner study
next to the
ceftriaxone failure is that he never used any of the scientifically
valid markers
of illness identified by IDSA, when we himself knew there were at
least matrix-metalloproteinases
in the spinal fluid of most of his seronegative Lyme victims, GFAp and
quinolinic
acid in the spinal fluid which shows chronic meningitis resulting in
the degradation
of the central nervous system, autoantibodies to nerve tissue,
dysregulated cytokines,
brain evoked potentials slowing (QEEG), gadolinium contrast MRIs of
monkey Lyme
brains show chronic meningitis, and that Lyme results in ALS and MS.
Mark Klempner knows these things, and he was clearly aware of the
parallel study
going on at the NINDS where Roland Martin was treating MS-Lyme
patients with both
antibiotics and MS medicines. Klempner is the author of the studies
where ceftriaxone
failed and of the discovery of the MMPs in the spinal fluid of
neuroborreliosis
patients.
That Klempner would dare to suggest that Lyme victims are
responding to the
antibiotics due to the "placebo effect" is a sure sign that Klempner
thinks
all MDs are morons, and he would be right, since none of your authors
has an MD
degree, yet this is simple science. Klempner's history is obvious to
a person
with the curiosity of a 7 year old.
VII. The Nutcase Anthony Fauci.
Now recall that in the summer of 2003 Anthonty Fauci lied his face
off on the
CNN Lou Dobbs show about the LYMErix vaccine. He said on the show the
exact opposite
of what I told the FDA Vaccine Committee which was that LYMErix was
not a scientifically
valid vaccine because Yale did not use a scientifically valid test to
assess for
it's efficacy. The Dearborn method misses 85% of the cases according
to the
Infectious Diseases Society's Gary Wormser. Said The Fauc' to Lou
Dobbs:
"We've had an effective vaccine, but it's the kind of vaccine
that you have to essentially vaccinate people each year. And from the
standpoint
of it's use, it has not been used as efficiently as it could have been
used.
So scientifically, we had a vaccine and still do have a vaccine, but
it's not
really well used."
Note that the summer of 2003 was over a year after LYMErix had
been withdrawn
from the market. Note also that the Dearborn standard only allows for
the inflammatory
kind of Lyme disease to be recognized, diagnosed and treated (granted
that Malawista
in his article where he recommended that the brain be thrown out said
that Lyme
arthritis should not be treated either because it goes away on its own
in 4 years).
Note also that in a PBS interview for their "Life on Earth" series,
Yale's
Eugene Shapiro said:
http://www.geocities.com/kmdickson0308/lyme-dilemma.html
SHAPIRO: What some people would have you believe is that
there are two
different diseases.
SHAPIRO: Somehow, for that form of the disease,
antibiotics are effective.
They do fine. But then there's some other form of the disease which
is, you
can't put your hand around it. They don't have objective findings of
inflammation,
which is the way bacteria cause disease.
So, there is Anthony Fauci, the head of NIAID, agreeing with the
Lyme criminals
that the only way a person could have a disease is if they have
inflammation. Of
course in the previous chapter, we proved that the immune suppression
outcomes of
Lyme disease due to tolerization to such fungal antigens as LYMErix
and the HIV
antigens gp120 and gp41 are likely to be the cause of all the New
Great Imitator
Neurological outcomes, such as Multiple Sclerosis, ALS, and the like,
through immune
suppression, the anchoring of the auto-kill kinases, and the
activation of latent
viral and infections and allowing for all kinds of opportunistic
infections, such
as mycoplasmal infections in the blood.
Amazingly, if one searches the patent database, one would find a
Fauci patent
for the treatment of immune suppression outcomes of bacterial, viral,
and fungal
infections:
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=5,696,079.PN.&OS=PN/5,696,079&RS=PN/5,696,079
FIELD OF THE INVENTION
The present invention pertains to a method for activating the
immune system
of a patient by intermittently administering interleukin-2 (IL-2) to
that patient.
Such administration of IL-2 can optionally be combined with other
therapies, such
as anti-retroviral, anti-bacterial or anti-fungal therapies, suitable
for treatment
of the patient's condition. This invention also relates to an approach
to gene
therapy that entails administering IL-2 to a patient so as to
facilitate in situ
lymphocyte transduction by a retroviral vector also administered to
the patient.
BACKGROUND OF THE INVENTION
Attempts at immune activation and restoration in the past have
utilized bone
marrow transplantation or lymphocyte transfers (H. C. Lane et al.,
Ann. Internal
Med. 113:512-19 (1990)), immunomodulating agents such as immuthiol (J.
M. Lang et
al., Lancet 24:702-06 (1988)) or isoprinosine (C. Pedersen et al., N.
Engl. J. Med.
322: 1757-63 (1990)), and recombinant cytokines such as interferon
alpha (IFN-.alpha.)
and IL-2. H. C. Lane et al., Ann. Intern. Med. 112:805-11 (1990); H.
C. Lane et
al., J. Biol. Response Mod. 3, 512-16 (1984); D. H. Schwartz et al.,
J. Acquir.
Immune Defic. Syndr. 4, 11-23 (1991); P. Mazza et al., Eur. J.
Haematol. 49:1-6
(1992); H. W. Murray et al., Am. J. Med. 93:234 (1992); H. Teppler et
al., J. Infect.
Dis. 167:291-98 (1993); P. Volberding et al., AIDS Res. Hum.
Retroviruses 3:115-24
(1987). These studies have resulted in minimal or only transient
immune system restoration.
The use of biologic response modifiers in general, and of IL-2 in
particular,
is an active area of clinical research. Interleukin-2 is a T cell-
derived lymphokine
with a number of immunomodulating effects including activation, as
well as induction
of proliferation and differentiation, of both T and B lymphocytes. K.
A. Smith,
Science 140:1169-76 (1988). Exogenous IL-2 has been shown in vitro to
increase the
depressed natural killer cell activity and cytomegalovirus-specific
cytotoxicity
of peripheral blood mononuclear cells from patients with AIDS, as well
as to increase
IFN-.lambda. production by lymphocytes from patients with AIDS. A. H.
Rook et al.,
J. Clin. Invest. 72:398-403 (1983); H. W. Murray et al., loc. cit.
76:1959-64 (1985).
It's a patented treatment for the immune suppression outcomes of
Lyme disease,
which is a condition simultaneously denied by the head of the National
Institute
of Allergy and Infectious Diseases- who owns this patent.
"It is an indescribable experience knowing that what you are doing
will
have an impact on the lives... of millions of people." --Anthony Fauci,
1993
Yeah, thanks, Ton'. It's been fabulous.
CHAPTER 12, CROOKS DEPLOY the MUMBO-JUMBO DUMBOS Deploying
scientifically invalid
psychiatry is a crime
http://www.ourladyswarriors.org/prayer/michael.htm
Saint Michael the Archangel,
defend us in battle.
Be our protection against the wickedness and snares of the
devil.
May God rebuke him, we humbly pray;
and do Thou, O Prince of the Heavenly Host -
by the Divine Power of God -
cast into hell, satan and all the evil spirits,
who roam throughout the world seeking the ruin of souls.
kshe...@calea.org, fit...@gmail.com, patrick.f...@usdoj.gov,
model...@sbcglobal.net, jdr...@nejm.org, let...@courant.com,
Jgerb...@cdc.gov, len...@courant.com, michae...@po.state.ct.us,
con...@po.state.ct.us, executiv...@nytimes.com, managing-
edi...@nytimes.com, news...@nytimes.com, the-...@nytimes.com,
biz...@nytimes.com, for...@nytimes.com, me...@nytimes.com,
nati...@nytimes.com, dv...@cdc.gov, brigidc...@optonline.net,
tr...@hotmail.com, ubi...@courant.com, ma...@concentric.net,
camp...@courant.com, jhorn...@fff.org, thomas...@usdoj.gov,
thoma...@po.state.ct.us, kur...@washpost.com,
georg...@washpost.com, hor...@courant.com,
commissi...@po.state.ct.us, cohen...@aol.com,
FalN...@aol.com, brans...@comcast.net, vts...@comcast.net,
o...@po.state.ct.us, da...@davila-dilzer.com,
scott....@po.state.ct.us, govern...@po.state.ct.us,
attorney...@po.state.ct.us, randall...@usdoj.gov
Cc: fra...@ucia.gov, dr-ahma...@president.ir,
eugener...@washpost.com, hor...@courant.com,
bmi...@newstimes.com, tr...@hotmail.com, rast...@aol.com,
billc...@gmail.com, thomas...@usdoj.gov, amcg...@rms-law.com,
rjmu...@aol.com, paulcrai...@yahoo.com,
sidney_b...@yahoo.com, criminal...@usdoj.gov,
karla.d...@usdoj.gov, christophe...@usdoj.gov
Subject: Said The Fauc' to Lou Dobbs...
Date: Jul 18, 2008 1:29 AM
http://www.actionlyme.org/MKLEMPNER.htm
√ CHAPTER 1, WHAT IS SCIENTIFIC VALIDITY? We do have a
scientifically valid
test for Lyme antibodies.
√ CHAPTER 3, STEERE, in EUROPE, CREATES "CRYME DISEASE" rules out
validity of The Dreaded Klempner Report
√ CHAPTER 10, BIOMARKERS OF DISEASE - developed by the crooks, not
deployed
by Klempner
Klempner_DQB1_0602.htm = Full transcript of July 2001 South
Country RI
Non-Diseases of Summer Conference obtained while Mark Klempner should
have been
wearing a muzzle instead of a "bullet proof vest."
Lyme is due to Fibromyalgia, which is "Catastrophizing":
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=DetailsSearch&Term=11083273[uid]|
and, according to Mark Klempner, it is cured by "the placebo effect
of
antibiotics" and is prevented by the first ever vaccine against
catastrophizing,
LYMErix.
Why was Mark Klempner elevated to the head of a CDC Level IV
Bioweapons
lab in Boston after committing such outrageous lies about "chronic
Lyme?"
Hear it straight from the horse's mouth:
http://www.youtube.com/watch?v=yPn_T9qy4C0&mode=related&search=
Bioweapons? Secret haplotypes? Vaccinating people with
known agents
of immune-suppression? Not warning parents that these same haplotypes-
questions
might apply to their kids re forced vaccinations-with-no-
compensations?
Hmmm. The plot thickens...
Chapter 11 - Mark Klempner's bogus "long term" or "re-treatment"
"study"
I. The NEJM Klempner Report (no peer review)
II. "Bogus Articles" (a real and deliberate phenomenon, includes
"Negative
Data Rule" concepts)
III. Ceftriaxone Failure/Intracellularity
MarkKlempner_Fibroblasts.htm = 1992 Klempner proves
ceftriaxone does
not kill all borrelia due to intracellularity
IV. MMP-130 (the study shows Mark Klempner knows we're very sick)
Retro_Klempnerization.htm = 1997 Klempner's famous MMP-130
study.
Proves "objective signs"
V. Dys/Autoimmunity (HLA-DQB1*0602, OspA-induced immune
suppression, latent
viral, fungal)
VI. Points of Refutation of the Validity of the Klempner Report:
A) Dearborn was bogus; we don't know what kind of
patients Klempner
had
B) 2/3rds of the patients never had IV ceftriaxone
before; this was
a standard of care study
C) Klempner threw out DNA positive victims from the
start
D) Klempner never reported primers (we don't care if we
have Borrelia
outermongolii)
E) No scientifically valid assessments of outcomes of
this standard
of care "study" were used
VII. The NIAID Nutcase Anthony Fauci and his patented treatment
for immune
suppression diseases
I. The Dreaded Klempner Report: >> http://content.nejm.org/cgi/reprint/345/2/85.pdf
← In July 2001, the New England Journal of Do-Do publishes nonsense
because they
have no peer reviewers who are competent to science. That is, there
aren't any
peers; there aren't people either non-interest-conflicted or
competent to the
science and likely both, because as you will see, the NEJM is getting
sloppier and
sloppier. We can at this point expect that NOTHING is not ghost
written by the
Bigs.
Two controlled treatment trials of chronic Lyme....
New England Medical Center and Tufts University School of
Medicine, Boston,
MA, USA. klem...@bu.edu
BACKGROUND: It is controversial whether prolonged antibiotic
treatment is
effective for patients in whom symptoms persist after the recommended
antibiotic
treatment for acute Lyme disease. METHODS: We conducted two randomized
trials: one
in 78 patients who were seropositive for IgG antibodies to Borrelia
burgdorferi
at the time of enrollment and the other in 51 patients who were
seronegative. The
patients received either intravenous ceftriaxone, 2 g daily for 30
days, [THIS WAS
THE ARBITRARILY DEFINED STANDARD OF CARE AT THE TIME FOR THIS CNS
BACTERIAL INFECTION-
30 DAYS OF IV CEFTRIAXONE] followed by oral doxycycline, 200 mg daily
for 60 days,
or matching intravenous and oral placebos. Each patient had well-
documented, previously
treated Lyme disease but had persistent musculoskeletal pain,
neurocognitive symptoms,
or dysesthesia, often associated with fatigue. The primary outcome
measures were
improvement on the physical- and mental-health-component summary
scales of the Medical
Outcomes Study 36-item Short-Form General Health Survey (SF-36)--a
scale measuring
the health-related quality of life--on day 180 of the study. RESULTS:
After a planned
interim analysis, the data and safety monitoring board recommended
that the studies
be discontinued because data from the first 107 patients indicated
that it was highly
unlikely that a significant difference in treatment efficacy between
the groups
would be observed with the planned full enrollment of 260 patients.
Base-line assessments
documented severe impairment in the patients' health-related quality
of life.
In intention-to-treat analyses, there were no significant differences
in the outcomes
with prolonged antibiotic treatment as compared with placebo. Among
the seropositive
patients who were treated with antibiotics, there was improvement in
the score on
the physical-component summary scale of the SF-36, the mental-
component summary
scale, or both in 37 percent, no change in 29 percent, and worsening
in 34 percent;
among seropositive patients receiving placebo, there was improvement
in 40 percent,
no change in 26 percent, and worsening in 34 percent (P=0.96 for the
comparison
between treatment groups). The results were similar for the
seronegative patients.
CONCLUSIONS: There is considerable impairment of health-related
quality of life
among patients with persistent symptoms despite previous antibiotic
treatment for
acute Lyme disease. However, in these two trials, treatment with
intravenous and
oral antibiotics for 90 days did not improve symptoms more than
placebo.
Unaware, perhaps, is the NEJM that Mark Klempner had previously
reported (1992)
that ceftriaxone failed to kill all the spirochetes due to
intracellularity and
unaware, perhaps, is the NEJM that Allen Steere published twice that
treatment fails
to eradicate all borrelial even after multiple courses of treatment in
about a third
of the cases... in the NEJM. You could call this stupidity, or, you
could call
it stupidity on the part of the NEJM, but I call it plain old
stupidity because
no matter how you look at it, the New England Journal is totally
incompetent.
You know, I don't know what's holding them back - the
Massachusetts
Medical Society could make a lot more money if they simply promoted
themselves as
an advertising agency.
II. BOGUS ARTICLES:
The first thing to know about Mark Klempner is that such a thing
as writing
"bogus articles" is well-established.
First known bogus article:
1992, Fikrig, as regards OspA vaccinations disinfecting ticks
using immunofluorescing
antibodies against stuff not expected to be there or washed away:
http://www.pnas.org/cgi/reprint/89/12/5418
As we know from Chapter 1, Fikrig had a scientifically valid
DNA method
to detect burgdorferi or even any of the other spirochetes, since this
is what his
Flagellin patent, US 5,618,533, is all about and the report associated
with the
patent was published in 1991. 1991 is before 1992 (this is a science
or math fact
that should be obvious, except for the part where we have people given
MD degrees
in America who clearly can't make this mental leap). Why didn't Fikrig
use
a DNA method to determine whether or not vaccination of mammals
disinfected the
ticks who later sucked on them?
Second bogus article(s):
Dressler/Steere with the funky strains in Europe (Chapter 3)
to come up
with the Dearborn standard testing schema. There is no such thing as
"receiver
operating characteristic" in the FDA's criteria for a valid
bioanalytical
method. The CDC's current, published diagnostic schema and standard is
a bogus
article. The ELISA misses all the neurologic cases in the first step.
Any treatment
outcomes where this bogus case definition of the disease was deployed
can be thrown
out as scientific garbage, as is the case with this 2001 Klempner
"study."
OspA gene bogus articles:
All treatment outcome articles where OspA primers were used
are bogus because
all these antigens undergo antigenic variation and we should be
looking for all
borrelia - not just burgdorferi - by using specific flagellin and
specific intragenic
spacer RNA. The Mouse Infectivity Test is the ultimate test because
of the difficulty
in reculturing spheroplasts without actual blood cells in the media
which are spirochete's
real food. People don't care which kind of Borrelia they have. They
don't
care if they have Lyme or Relapsing Fever as long as they're not
diagnosed as
DSM IV/ICD-9 Viagra Deficit Syndrome (VDS), Hyposexifemzalgiarrhenus
or Negapenia.
Over this "OspA is Lyme" business, the Czech Republic called Americans
stupid and incomprehensible.
Previous chapters reveal that we know how to perform
scientifically valid
tests for both identification of the disease itself (yet to come,
cysts and the
MIT or Mouse Infectivity Test), and markers or signs of illness,
meaning we have
no use for psychiatrists in the area of chronic illnesses.
All hospitals should have their own labs and equipment and
samples do not
need to be sent out to labs, because we have no use for insensitive,
invalid, "test
kits." Some labs, like Quest, even charge for test kits used in their
labs
and then have the audacity to disclaim that test kit test, and refer
you to another
lab for the real result. In other words, you may not know it until
you read your
own lab results, but you may be paying a lab to run a fake test kit
test, they'll
charge your insurance company or Uncle Sam for that test, but then
they literally
disclaim the results and literally refer you elsewhere to get a real
test for that
marker, and no one does a thing about it. It happens to be fraudulent
to be charging
someone for an invalid test, because not only is the result invalid,
time is lost,
and you have to pay for that test again. I have proof of this, which
is why I am
naming names: QUEST Labs.
So, we know how to run scientifically sound tests on people to see
in what way
they are sick. We can perform radioimaging (SPECT, MRI), tests, and
we can use
specific antibody tests, expanded antibody tests (antiphospholipids,
antigangliosides,
anti-heat-shock proteins), and we can look for dysregulated cytokines
in the blood.
We can look for immune complexes in the blood. We can perform spinal
fluid analyses
to look for gliosis (destruction of glial cells), cytokines
dysregulated monoamines
and we can do electromyography. We can look for matrix-
metalloproteinases that
should not be there and quinolinic acid in the cerebrospinal fluid (a
marker of
infection). We can perform DNA and RNA tests to look for viruses and
bacteria.
We can look at cells to see if they are aberrant-looking, etc. We can
perform a
whole slew of tests on people to see if they're sick.
Enter Mark Klempner;
WHEREUPON, scientifically valid testing is never done, even to the
tune of 4.7
million dollar grants to a guy who found out the reason ceftriaxone
failed to cure
people was probably due to the intracellular spirochetes. Mark
Klempner also happens
to be the guy who found a specific marker of Lyme bacterial
infiltration into the
central nervous system and said he found this specific MMP-130 marker
in no other
diseases of the central nervous system.
And then he said we have no disease at all for that 4.7 million
dollar grant.
And then he was promoted to the head of a CDC bioweapons level IV
lab in Boston.
So, is Mark Klempner and the Lyme/LYMErix fiasco a result of the
Bigs (Insurance
and Pharma) in concert with the lying patent profiteers of the CDC or
is this a
bioweaponeering bumbler situation (cover-up of an accidental release
from Plum Island),
or is it both? Or is it yet a third condition to be suspected as a
result of the
libelous "NAZI" and other bizarre accusations and statements by the
Israeli
Durland Fish?
Is this fraud due to CDC personal biopatent weaponeering or
BigInsurance interfering
or is a third party entitled to the information that we paid for but
are not allowed
to have? We know it is true from Sibel Edmonds and the State
Department's Marc
Grossman that Israelis are here in the USA infiltrating the
universities and nuclear
facilities to steal intelligence (bio and nuclear) despite their self-
allegation
of being the intellectual elite (why do they have to steal information
if they're
all brilliant?). We have seen the Israeli Durland Fish flatter the
would-be NIH
"scientist" Edward McSweegan to get McSweegan to perform the dirty
work
for Fish, such that Fish could trash the Lyme Disease Foundation's
Karen Forschner
because of Karen's discoveries that refute the nonsense the ALDF.com,
Yale and
CDC cabal spew. We know who the ALDF's financial backers are (e.g.,
Mortimer
Zuckerman, the AIG Greenbergs, etc.). The FBI is not interested in
protecting us
from corporate crime because their focus is porn, unaware are they
that they are
perceived as, in the words of Henry Kissinger, "dumb, stupid animals
to be
used as pawns for political purposes." The New Haven, Connecticut,
FBI cannot
even be insulted into reality, confirming the "dumb, stupid animals"
allegation.
The evidence is that the crooks want to promote another OspA
(trivalent, Baxter)
vaccine, but we think that's a cover for the first crime, which was to
claim
there was no neurologic Lyme disease. This lie was invented to falsely
state that
there was no neurologic disease outcome as a result of vaccine failure
or the immune
suppression results (which we think are the same thing) of OspA
vaccination.
In a complaint to the Israeli Michael Chertoff in August 2005, it
was reported
that:
27) Martin J. Mattessich President & CEO, Director
"Prior to
becoming President and CEO of Agilix, from 1996 to 1999 Mr. Mattessich
was the co-founder
of two Yale University-sponsored biotechnology companies, L2
Diagnostics, LLC (diagnostic
serology) and polyGenomics, Inc. (gene discovery for polygenic
diseases) , and a
consultant to CuraGen Corporation, a publicly held genomics company
(pharmaceutical
drug ...."
With the blood he intended to get from the L2 Diagnostics-
Imugen nationwide
monopoly on testing, they can identify new diseases to commercialize.
We Americans are pretty stupid people, huh? When will we get it
that the "government"
is not set up to serve the interests of the people? How many times do
we have to
be smacked upside the head before we realize that the only thing we
can do is request
that other nations kidnap and torture our biowarfare criminals like
CDC officers
and several members of the NIH?
III. Bearing in mind that ceftriaxone is a meningitis drug - a
clue to the fact
that Lyme is a brain disease and not a knee disease - Mark Klempner,
in 1992, found
that the reason ceftriaxone did not kill all the Lyme spirochetes was
that they
were intracellular. Intracellularly, these spirochetes are protected
from the toxic
effects of antibiotics. Alan Barbour reported that in the presence of
antibiotics,
these spirochetes reverts to the cyst or spheroplast form, which we
all know to
not be the end stage but rather a dormant or self-protection stage.
The intracellularity
of spirochetes has been well-known for a hundred years. Intracellular
spheroplast
dormancy is what characterizes these permanent spirochetal
infections. Klempner
went with this stupid 4.7 million dollar study anyway, knowing the
reason ceftriaxone
failed. We can tell from his conclusions that this "study" was
conducted
because that he/they intended not to allow us to be treated with
ceftriaxone regardless
of the truth.
IV. The second most important study published by Mark Klempner was
the matrix-metalloproteinase
study where he found that 78% of neuroborreliosis patients had MMP-130
in their
spinal fluid, and he found that to be a SPECIFIC marker. That is, he
did not find
this particular nerve and brain degrading enzyme in people with other
neurological
disorders.
This is a pretty amazing report because Klempner later said there
was no evidence
that Lyme causes cognitive impairment, when his argument for studying
MMP-130 was
because of the cognitive impairment in Lyme.
If the Lyme criminals claim "chronic bad-knee-Lyme" is an
autoimmune
disease due to the hyperbinding of OspA to Steere's haplotypes, then
why shouldn't
people imagine believe there isn't either a binding or a non-binding
autoimmune
phenomenon going on in neurologic Lyme instead of saying such a thing
does not exist?
But, we're not saying chronic neurologic Lyme is strictly an
autoimmune
disease, like Steere is saying (fraudulently) that his kind of chronic
Lyme is an
autoimmune disease. We're saying, A) there is more than one mechanism
of autoimmunity
or immune dysregulation, so there does not have to be an either
binding or non-binding
phenomenon going on; there could be other mechanisms [errant cloning
of either B
cells or T cells (pseudolymphoma), immune suppression due to tolerance
and down-regulation
of HLA, disturbed pathways of either HLAs or TLRs, disturbed signals
from disturbed
cytokine production, cytokines acting as neurotransmitters, antibodies
acting as
neurotransmitters, etc.,...]; and B) persisting infection is not
independent of
autoimmunity, no matter what kind of autoimmunity. It's not either/
or. Chronic
borreliosis is definitely persisting infection, but it also could be
autoimmune
neurologic disease. It is likeliest immune dysregulation process sets
in combination
with persisting infection. The immune suppression outcomes of
tolerization to shed
borrelial antigens renders people susceptible to opportunistic
infections and the
exacerbation of latent viral and other infections of all kinds which
could be the
cause of the New Great Imitator outcomes. The immune suppression's
resultant
exacerbation of viral and bacterial or mycoplasmal infections of all
kinds could
be the secondary causes of autoimmunity. The possible mechanisms of
illness are
infinite. Instead of trying to discover why people are sick for the
benefit of
revealing that information to others, this information is being kept
private by
the cabal.
As we have seen in the chapter on BIOMARKERS, the suppression of
the science,
here, on immune suppression outcomes of Lyme Disease and LYMErix, has
negatively
affected all other chronic and fatal diseases. Their crimes are not
just against
people bitten by ticks.
QUI TAM and RICO- Recover the money (temporarily suspend the
reality where
the government no longer is about protecting the people):
One way to to stop the tsunami of bovine excrement from the Steere-
CDC camp
is to force them to retract all of their "bogus articles" and start
over,
particularly with the moneys recovered by those who profited- and
attempted to profit
from- this spin, like the insurance companies. So far, the Lyme
crooks have not
profited in the way they intended since LYMErix was withdrawn,
trashing their intended
monopoly on testing. But they have taken fraudulent income from the
government,
so the individual prosecutions of the Lyme perps will come as
separate, individual
Qui Tam fraud cases. The crooks made false claims to the government
in order to
get more funding to spin out more nonsense tales, like Klempner's 2001
"repeat
treatment," "study." Whenever they applied for a grant on the basis
of Dearborn being a reality, that is a false claim for grant money.
They clearly
also made false claims on behalf of BigInsurance, since Kaiser bailed
out the financially
failing New York Medical College and they're still there at New York
Medical
College, training MDs. That happened at the same time as the
establishment of the
ALDF.com which was right after the 1989 IDSA Review of Infectious
Diseases. special
publication about how serious Lyme was and that the treatment endpoint
was unknown.
As stated in the introduction:
The Lyme crymes and the cabal - The 180s - are about an
intended monopoly
on vector borne diseases "test kits" and "vaccines" and could
not have happened without the Bayh-Dole Act. The monopoly involved
Kaiser-Permanente
(still) at New York Medical College and the deal was:
No one is allowed to have any illness signs nor is
treatment to be paid
for, until the alleged "vaccine" is ready, and then everyone will be
notified
about how serious that particular vector borne disease is, and that
they better
get the "vaccine."
This appears to be the agreement between the biotech patent
profiteers and
Kaiser-Permanente at New York Medical College, which was in financial
trouble in
1990 under the leadership of John J. Connolly, leading to the
establishment of the
false front non-profit called the American Lyme Disease Foundation
Recall that
when charging a RICO, one does not have to prove the parties sat down
together and
made deliberate statements and signed agreements about their intended
crime. There
merely has to be the appearance that there was an agreement.
http://www4.law.cornell.edu/uscode/18/1961.html
(4) "enterprise" includes any individual, partnership,
corporation,
association, or other legal entity, and any union or group of
individuals associated
in fact although not a legal entity;
This we can prove due to the abundant statements made by the
ALDF.com cabal
about how serious and dangerous Lyme Disease is when they wanted to
sell their bogus
vaccine:
"It is well known that Borrelia burgdorferi indeed after
asymptomatic
infection can lurk or secrete itself in certain areas of the body,
perhaps the central
nervous system or perhaps the joint spaces, only to reappear months or
maybe years
later in the form of late stages of illness which are harder to
diagnosis and treat.
"It is probably worth noting, since I have learned a lot, that
we don't
have the clinical luxury in private practice that we had in the
SmithKline Beecham
trial in which we had baseline sera on all the patients who enrolled
so that when
they presented with symptoms, we could draw acute and convalescent
serologies [recall
that that was the old diagnostic standard- see Chp 3] so as to compare
them with
each other and with baseline to better understand what symptoms they
are presenting
with.
Finally, there are indeed many dilemmas in therapy. In
particular, untreated
or inadequately treated Lyme disease may lead to the chronic morbidity
with which
we are very familiar. Most commonly arthritis and the not common but
complex neurological
syndromes are what often result and which confront the primary care
physician in
the office diagnostically and therapeutically.
These particular outcomes result in much more intensive, long-
term expensive
therapy, often in the form of long-term intravenous antibiotics.
These are the
patients who often are refractory to treatment. Indeed, these are the
patients
in whom symptoms seem to persist despite what we have given in terms
of adequate
antibiotic therapy by any known measure.
In conclusion, we need a vaccine for Lyme disease because it
is increasing
in incidence and geographic spread. We need a vaccine for Lyme
disease because
there are problems in clinical diagnosis, its laboratory evaluation,
and its treatment.
We need a vaccine for Lyme disease because preventive measures are
unfortunately
ineffective. Lyme disease is indeed vaccine preventable.
Availability of this
vaccine would lead to a significant reduction in chronic sequelae and
substantive
morbidity. Lyme vaccine is thus a critical new public health approach
to the primary
prevention of Lyme disease in the United States. Thank you very
much."--
Vijay Sikand, EAST LYME, CT to the FDA Vaccine Committee in 1998
All in all, the original USDOJ July 2003 claim of "scientific
fraud and
racketeering" was correct. I researched the crime and the laws
thoroughly
before filing the RICO complaint with the USDOJ.
It was FRAUDULENT for Mark Klempner to use a check list to assess
patient outcomes
when he knows there is a very specific marker in the CSF for damage,
and a rational
person would wonder if the presence of this nerve degrading enzyme was
diminished
with a month of ceftriaxone treatment. 'Not to mention utterly crazy
to try
to sell a vaccine for a disease over which Mark Klempner was at that
very moment
(Klempner's study started in 1997) engaging in a bogus protocol
intended to
prove Lyme disease- that terribly morbid chronic condition over which
Vijay Sikand
begged the FDA Vaccine Committee to approve LYMErix - does not exist.
There is no question, thanks to Mark Klempner, that we can validly
claim that
LYMErix was a placebo vaccine against Lyme hysteria. It was the
world's first
ever placebo vaccine and one that Yale said everyone in the country
would need
every year. LYMErix was the first ever vaccine against
catastrophizing.
And no one in the Connecticut, New York or Massachusetts
boards of health
or medical boards said a word. They STILL haven't said a word about
this placebo
vaccine against hypochondria...
And the funny thing is, this cabal intends to repeat the exact
same ridiculous
proposal:
Journal home > Archive > Correspondence > Full Text
Correspondence
Nature 440, 278 (16 March 2006) | doi:10.1038/440278b
Lyme vaccine demonized by advocacy groups
Edward McSweegan1
1. 1692 Barrister Court, Crofton, Maryland 21114, USA
Sir:
As a microbiologist who managed a federal programme on Lyme
disease in the
1990s, I consider that any new clinical trials of a vaccine candidate
based on the
protein OspA, as mentioned in your News Feature "Uphill
struggle" (Nature
439, 524-525; 2006), should be confined to Europe, for three reasons.
First, Lyme disease is non-communicable, readily treatable
with common antibiotics
and geographically localized in the United States. Neurological cases
-- where treatment
can be problematic -- are more common in Europe and a new vaccine may
reduce the
costs and consequences of infection.
Second, European experience with the widely used tick-borne
encephalitis
virus (TBEV) vaccine may facilitate vaccine-trial recruitment and
greater public
acceptance of a new Lyme vaccine.
Third, Europe is a less litigious environment and is largely
free of organized
Lyme-patient advocacy groups. In the United States, activists have
turned Lyme disease
into everyone's backyard bogeyman. They have demonized experts for
their views
on treatment and prevention, and hired lawyers to successfully argue
the dangers
of vaccine-induced autoimmunity (Philadelphia Inquirer B03, July 9
2003).
The activists are already using Internet discussion groups to
warn against
a new vaccine. One of them recently wrote "I would encourage all Lyme
patients
to consider writing letters, emphasizing the lack of demand for the
last vaccine,
and also the fact that any future vaccines can expect a lack of
cooperation, protests,
legal quagmires, etc."
A careful, hysteria-free trial of the new OspA vaccine
[remember now, OspA
is a placebo vaccine against hysteria] in Europe may help to undermine
the opposition
to it in the United States.
You'd really have to be a world class jackass to propose that Lyme
is not
dangerous while at the same time saying Lyme is so dangerous that we
need a vaccine
against it. Here McSweegan says he needs a hysteria-free trial of a
new OspA vaccine
-- which Mark Klempner says is a placebo vaccine against hysteria
because, Klempner
said, Lyme is a non-disease cured by "the placebo effect of
antibiotics."
We have never seen a more insane set of American scientists
continually get their
insanity published.
And, ahem, I add that LYMErix, I said (TO THE FDA VACCINE
COMMITTEE in JANUARY,
2001), caused an immune dysregulation syndrome and not autoimmunity:
http://www.fda.gov/ohrms/dockets/ac/01/slides/3680s2_11.pdf
Ya see, because I am a real scientist, which means I have no
preconceived ideas
about data. I let the data tell me what to do, and not the other way
around. I
am not a man and do not get all jerked off and whack my pee-pee on my
time off (nor
post penis data on the Lyme newsgroup, like Yale's Durland Fish), nor
do I pretend
the whole world happens because of sex or me or my pee-pee. If
anything, the absence
of a penis is a godsend, because we women can think so much more
clearly than any
of these self-alleged scientists or MDs. Clearly Mr. Peanut is a
major distraction
even in the world of vaccines. Yale's Steven Malawista literally
declared that
the brain should be thrown out because it is "a complicating
variable."
He really got that insanity published in a journal:
"I have largely limited the discussion here to Lyme arthritis,
the
simplest case because the end point (no more arthritis) is so clear,
and one does
not have to introduce complicating variables such as the blood-brain
barrier."
--- Stephen Malawista, Yale University
I wonder if castration would help in more of the DSM disorders
than the sex-OCD
so common to psychiatrists? Clearly McSweegan, Klempner and Malawista
are out of
their minds, but remain free and unmedicated. They remain free and on
the loose;
free to publish scientific insanity that is "dangerous and harmful to
others"
in the medical journals. I have said many times that Dante's Inferno
needs
to be updated to include a new circle of hell for people who try to
pass off such
utterly crazy shit as medicine.
Yale is the anus mundi.
V. Dysimmunity and the Other Secret Multiple Sclerosis Haplotype
(HLA-DQB1*0602)
The following is the transcript of what Mark Klempner secretly
told the attendees
of the Non-Diseases of Summer Conference at South County Hospital in
Rhode Island
on approximately July 21, 2001 (it remains a secret, but blows away
all of Klempner's
conclusions):
"And, that is, that when you look for the possibility of an
autoimmune
disease, the best way to look is to see if there is any genetic
clustering in HLA
haplotypes. The reason for that is the way antigens get presented in
the context
of who you are, that is, your HLA haplotype. And we can talk in some
detail about
that. Those diseases that I think everybody would agree are so called
Autoimmune
:lupus, rheumatoid arthritis, type 1 diabetes, and perhaps MS, have
some clear genetic
clustering that leads us to believe that these are indeed autoimmune
diseases, although
we do not satisfy so-called Koch's Postulates of autoimmune disease
that we've written[?-KMD]
about. And the odds ratio for your having that particular HLA type,
in the case
of R.A, a DR4, or a DQB0602 to protect you from type 1 diabetes, are
on the order
of 3 to 6. One of the ones that is probably highest, of course, is
B27, in patients
with alkyloiding spondolytis and the like. It turns out that if you
look at the
first 51 patients with post-treatment chronic Lyme disease, the
patient population
that participated in our study, there was a very high incidence of
DQB0602 with
an odds ratio of 770%. So it may well be that exposure to THAT
organism with THAT
background of HLA haplotype may lead you to develop chronic symptoms.
That is a
hypothesis that needs to be tested. It would obviously lead to an
entirely new
form and approach to therapy. "
http://www.youtube.com/watch?v=yPn_T9qy4C0&mode=related&search=
Hear this very big secret not for large dissemination straight
from the horse's
mouth. There were no questions by the MD-crowd at Rhode Island's
South County
Hospital about this HLA secret. None of the physicians questioned
it. They just
all pretended to understand what Mark Klempner was talking about. I
think pretending
to know what a medical scientist is talking about when you are an MD
is a mental
disorder that should be added to the DSM-V.
Like, there was no mystery to these Rhode Island MD morons when
Mark Klempner
said there was no disease at all, but that he discovered this
autoimmune neurologic
haplotype that they're supposed to "not largely disseminate found at
an
8 times higher rate than would be expected due to chance in all these
fricking Yuppie
disease-wannabee whiners who would otherwise have nothing to talk
about cocktail
parties and Fibromyalgia is a women's disease related to the boredom
associated
with low innate intelligence and a frustrated desire to be a soap
opera star."
Not a one of them said, "SO YOU FOUND SOMETHING WRONG WITH THESE
PEOPLE,
DR. KLEMPNER???" They instead swooned and kissed his butt and asked
if he
was a victim of us crazy Lyme victim terrorists. They fed this
bastard's ego
instead of having a single independent thought among the fifty or
hundred or so
of them. Rhode Island is a very, very stupid and backward place.
'Even stupider
than southeastern Connecticut if that were possible.
In a follow up study published in 2005, Klempner and Wormser
reported that there
is no association between haplotypes and Chronic Lyme:
http://www.journals.uchicago.edu/doi/pdf/10.1086/432733
In this report they say that the chronic-knee people generally
feel well, except
for their arthritis symptoms. This we suspected just from our limited
experience
with such rare victims, and also due to a statement from Vijay Sikand
at the 1998
LYMErix vaccine meeting where Sikand states that these arthritis
people could be
considered "immune competent," or are able to make enough antibodies
to
fight off infection. They say that this is a blinded study and that:
First, we suspect that this is untrue in that these criminals play
a primers
shell game, as previously mentioned. Secondly, this supports the
notion that it
is the immune suppression-exacerbation of latent common infections
(Epstein-Barr,
Mycoplasma in the blood, Cytomegalovirus, etc.) caused by chronic Lyme
Disease and
LYMErix vaccination, due to the tolerization of fungal antigens
(downregulation
of HLA molecules) and the inhibition of the auto-kill kinase mechanism
induced by
OspA as discussed in the Biomarkers chapter (10).
Mark Klempner reported that OspA could cause cross reacting T
cells to neurologic
tissues. He reported in 1998 that:
"T cells that react to OspA, OspC, and p22 epitopes also
recognize
MOBP, SST-R1, and IL-R1, respectively, on neurons, possibly leading to
encephalopathy
and radiculopathy. T cell recognition of synovial and neuronal
proteins can cause
chronic symptoms for years after the initial infection. It is not
known whether
the spirochete is still present during this chronic stage, or whether
symptoms are
strictly due to T cell autoimmunity."
Klempner says here that OspA (either from the bug or from
vaccination) could
cause an autoimmune disease of the nervous system. This possibility
(not fact)
was never mentioned in his "chronic Lyme" "study," yet clearly
this report was published in 1998, when Klempner's "chronic Lyme"
"study" was ongoing and clearly no new evidence emerged on persistence
of the infection. Klempner also reported in 2003 with a University of
Connecticut
"ass ociate" (Kaplan) that there was no such thing as cognitive
impairment
associated with "Lyme Disease."
We agree that that's a no-brainer, since there is no such thing as
"Lyme
Disease." "Lyme Disease" is an imaginary self-limiting arthritis
in a knee that needs no antibiotic treatment, but it does apparently
need a bogus
vaccine.
Klempner never reported this information about OspA vaccination
possibly being
the cause of an autoimmune brain disease to the FDA nor said something
about it
after the FDA approved LYMErix. They guy is the ultimate low-life.
All of this data, including a complete dub, a tape, of this July
2001 Klempner
lecture in Rhode Island along with a transcript, was given to the US
Attorney in
Connecticut who did nothing about it and then was promoted twice in
the USDOJ.
CT Attorney General Richard Blumenthal and his staff then had to take
over the US
Attorney's job for him without the federal pay and the DOJ resources.
After committing the crimes of LYMErix and this fake long term or
repeat treatment
"study," Klempner was promoted to the head of a CDC Level IV
bioweapons
lab in Boston. This should be seen as a criminal endorsement, such as
US Attorney
Kevin O'Connor of the District of Connecticut being promoted to
Alberto Gonzales'
Chief of Staff, and then when Gonzales went down, O'Connor was given
the Number
Three position at the United States Department of Justice (sic).
Crooks in government are promoted and whistleblowers get the bag
job, since
we're talking Republican whores, here, which is the only kind of
Republicans.
Is the US not about to undergo a bigger financial collapse than the
Great Depression?
Who outsourced us? Who sold out our rights to the corporations?
About the likes of even the local whores, like Cathy Cook (R-
Mystic, CT) and
Rob Simmons, former Republican Congressman from Stonington,
Corrupticut, we say
"We grows da hoes big around he-yuh,... since Pfizer is nearby and we
use almost
literally use Viagra as fertilizer ta grow duh Republican hoes."
Repeat after me, class:
1) Klempner found that spirochetes are intracellular and resistant
to ceftriaxone.
2) Klempner found that Lyme is a chronic infection that causes
degradation of
the central nervous system.
3) The haplotypes data was not reported in Klempner's Long term
treatment
report but a subsequent article by Wormser and Klempner indicate an
increasing likelihood
that Chronic Neurologic Lyme is the New Great Imitator due to the
immune suppression-related
exacerbation of latent viral and acquired fungal infections of all
kinds, rather
than neurologic autoimmunity. Given the fact that OspA is the source
of the immune
suppression, that alone could be the cause of the cover up
(vaccination with OspA
and the cover up of the damages- the New Great Imitator outcomes of
LYMErix). While
we once thought there must be some association with Multiple Sclerosis
haplotypes
allegedly secretly found in chronic neurologic Lyme and the tolerance
to Pam3Cys-related
downregulation of the antigen-presenting cells (and the subsequent
cessation of
antibodies to these antigens or the person becomes "seronegative"), it
now appears there was no association. It could happen to anyone.
We knew about the immune dysregulation in 1992 from the NIH's, the
NCI's
and the US Army's Paul Duray when he revealed the mutated lymphocytes
and stated
that these looked like Epstein-Barr transformed cells. None of this
was pursued
because scientific discovery could interfere with the intended
propaganda or marketing
of LYMErix.
4) Mark Klempner suggested in 1998 that LYMErix could be causing
an autoimmune
neurologic disease but did not report this to the public, ever, as a
reason for
concern or a reason to withdraw LYMErix.
5) Klempner was promoted by the CDC to the head of a CDC Level IV
bioweapons
lab for his outrageous lies to and about the public.
=======================================
VI. The following facts refute the validity of the Klempner "long
term"
treatment "study," published in the New England Journal of Malarkey on
July 12, 2001:
A) The CDC positive "case definition" has never been proven to be
accurate or valid for late, treated Lyme, which were the patients
Klempner claimed
to be "studying." It was never proven to be a valid method to detect
Lyme in the first place. No one knows what, exactly, the Dearborn
case "definition"
criteria means, since no one agreed with the Steere IgG proposal at
the 1994 CDC
Dearborn, MI, self-alleged conference, self-alleged to be about
"Standardization
of Western Blotting." Steere never validated his IgG Dressler/Steere
method
according to the FDA rules for the validation of an bioanalytical
method. The participants
in the Dearborn conference said Steere's IgG proposal was 8-28%
accurate when
tested in the field.
When Steere tested his own proposal in the field, he found that 39
of 54 arthritis
patients were positive to his IgG panel proposal of 18, 23 (OspA), 28
(porin), 30,
39 (flagellar sheath), 41 (flagellin), 45 (porin), 58, 66 (porin), 93
(Could be
31 times three, or it could be the specific brain invasion antigen
that the Europeans
claim). We actually have no idea what Steere observed, since he
obtained this "data"
with bogus, NIH- and CDC- NOT-recommended strains from Guilford, CT,
Germany and
Russia, and to boot, they were all "HIGH PASSAGE" (strains FRG and
high
passage G39/40). Since we don't know what "Dearborn positive" means
in previously treated patients, we have no idea what kind of patients
Mark Klempner
had. Even the participants of the CDC's bogus Dearborn conference,
(Phil Molloy)
said ~ "We have no idea what Dearborn means." Therefore, the only
real
result Mark Klempner had from this "study," was that 78 out of 1800
patients
tested Dearborn positive after some antibiotic treatment (accuracy of
Dearborn Lyme
is 4% in treated patients).
B) Klempner's "study" was supposed to be a "repeat treatment"
"study" of previously treated Lyme victims, when most (2/3rds) had
never
had previous IV ceftriaxone treatment. He already knew the reason
ceftriaxone failed
to cure. At the time of the proposal of the Klempner study protocol,
the standard
of care was 30 days of intravenous ceftriaxone- which was an arbitrary
determination
in the first place. The standard of care was 30 days of intravenous
antibiotics
at the time of the Klempner "study," since that's the standard mode
of delivery of antibiotics for brain infections or meningitis and was
in use for
years.
Thus, Klempner's "long term re-treatment study," was a "standard
of care study," and it showed that 30 days of the IV drug used for
bacterial
infections of the brain or meningitis was not enough intravenous
antibiotics and
that the chronically fatigued, neurologically and cognitively impaired
victims of
Klempner and Lyme should have been given at least 2 months of
ceftriaxone.
It was always known that borrelioses are permanent brain
infections and Relapsing
Fever. Therefore we would expect that Lyme should be treated as a
Relapsing Fever
brain infection, and that the treatment of its victims should be
relapsing IV ceftriaxone.
No one says these things because they are logical. What we know now
from the Fallon
study is that one should start with at least 3.5 months of intravenous
ceftriaxone
and if patients relapse after that, perhaps add another month. And if
they relapse
after that, repeat. Somewhere along the line it became acceptable to
tell people
it's okay if they remain chronically miserable, when the same people
know of
a treatment that brought relief (Dattwyler 12821734). Amazingly,
these bizarro
facts have never, ever once made it into any media, much less main
stream media.
The MDs don't ask any questions and the newspapers have forgotten the
part about
investigating unanswered questions. The media and the AMA and the DOJ
totally accept
hypocrisy to the point where they're convinced they're the guardians
of
the corporations rather than the people. I feel like I'm watching that
black
kid in Florida DCF pediatric prison being beaten to death by several
prison guards
for being a juvenile thug on a national scale. This country is so
screwed up and
the victims are so routinely tortured and we're so used to it, that
the next
thing we can expect is a new wave of New Roman Coliseum Theatres
moving back into
the towns with the lions and the blood and guts and gore as a new way
to treat sick
people... and then we'd have to listen to the animal rights people
crusading
over the poor lions' diet.
C) Klempner threw out PCR positive patients and then lied about
it. Klempner
reported that no PCR-positive patients were included in his study. He
stated right
in the full text NEJM article that he did not accept PCR positive
victims in his
study. There were PCR positive Klempner victims who were excluded from
the "study"
because they were positive and this is known to the Lyme community
since these rejectees
are part of the Chronic Lyme community. In the audiotape of Mark
Klempner at the
South County Non-Diseases of Summer Conference in July 2001, Klempner
said that
out of 2000 patients, none were DNA positive for the Bb DNA in their
spinal fluid.
Klempner is a liar.
D) Mark Klempner never published what primers he used to determine
"DNA
negative" in the spinal fluid of his victims. As we have seen in
previous
chapters, one must use genus-specific primers such as multiple
Borrelial (from several
of the genera) flagellins and intragenic spacers (RNA) that identify
Relapsing Fevers
(or Borreliae). Klempner claims to have used a culture method when we
all know
and knew culture is inferior to DNA/RNA testing or the Mouse
Infectivity Test.
When asked directly to reveal what primers he used, Mark Klempner
refused to reply.
According to IDSA's Russell Johnson, it "could take months" to recover
intact spirochetes from the spheroplast form in BSK media. Klempner
only attempted
to reculture spheroplasts from spinal fluid for 3 weeks.
E) No Scientifically Valid Tests Used to Assess Outcomes, and then
he claimed
hysteria to be the cause of the illness. Klempner even claimed that
people who
got better from treatment were reporting merely "a placebo response to
antibiotics."
The Fibromyalgia Impact Questionaire (FIQ) was invalidated rather
than validated
for use in Lyme victims. Arthur Weinstein has proposed method
validations in the
past which are not validations. In the case of the FIQ, he found that
Fibromyalgia
and Lyme disease were two different diseases. If they are two
different diseases,
the test or the method itself is not valid, since a validation
requires that the
test is SPECIFIC to the analyte in question.
The second most glaringly ridiculous aspect of the Klempner study
next to the
ceftriaxone failure is that he never used any of the scientifically
valid markers
of illness identified by IDSA, when we himself knew there were at
least matrix-metalloproteinases
in the spinal fluid of most of his seronegative Lyme victims, GFAp and
quinolinic
acid in the spinal fluid which shows chronic meningitis resulting in
the degradation
of the central nervous system, autoantibodies to nerve tissue,
dysregulated cytokines,
brain evoked potentials slowing (QEEG), gadolinium contrast MRIs of
monkey Lyme
brains show chronic meningitis, and that Lyme results in ALS and MS.
Mark Klempner knows these things, and he was clearly aware of the
parallel study
going on at the NINDS where Roland Martin was treating MS-Lyme
patients with both
antibiotics and MS medicines. Klempner is the author of the studies
where ceftriaxone
failed and of the discovery of the MMPs in the spinal fluid of
neuroborreliosis
patients.
That Klempner would dare to suggest that Lyme victims are
responding to the
antibiotics due to the "placebo effect" is a sure sign that Klempner
thinks
all MDs are morons, and he would be right, since none of your authors
has an MD
degree, yet this is simple science. Klempner's history is obvious to
a person
with the curiosity of a 7 year old.
VII. The Nutcase Anthony Fauci.
Now recall that in the summer of 2003 Anthonty Fauci lied his face
off on the
CNN Lou Dobbs show about the LYMErix vaccine. He said on the show the
exact opposite
of what I told the FDA Vaccine Committee which was that LYMErix was
not a scientifically
valid vaccine because Yale did not use a scientifically valid test to
assess for
it's efficacy. The Dearborn method misses 85% of the cases according
to the
Infectious Diseases Society's Gary Wormser. Said The Fauc' to Lou
Dobbs:
"We've had an effective vaccine, but it's the kind of vaccine
that you have to essentially vaccinate people each year. And from the
standpoint
of it's use, it has not been used as efficiently as it could have been
used.
So scientifically, we had a vaccine and still do have a vaccine, but
it's not
really well used."
Note that the summer of 2003 was over a year after LYMErix had
been withdrawn
from the market. Note also that the Dearborn standard only allows for
the inflammatory
kind of Lyme disease to be recognized, diagnosed and treated (granted
that Malawista
in his article where he recommended that the brain be thrown out said
that Lyme
arthritis should not be treated either because it goes away on its own
in 4 years).
Note also that in a PBS interview for their "Life on Earth" series,
Yale's
Eugene Shapiro said:
http://www.geocities.com/kmdickson0308/lyme-dilemma.html
SHAPIRO: What some people would have you believe is that
there are two
different diseases.
SHAPIRO: Somehow, for that form of the disease,
antibiotics are effective.
They do fine. But then there's some other form of the disease which
is, you
can't put your hand around it. They don't have objective findings of
inflammation,
which is the way bacteria cause disease.
So, there is Anthony Fauci, the head of NIAID, agreeing with the
Lyme criminals
that the only way a person could have a disease is if they have
inflammation. Of
course in the previous chapter, we proved that the immune suppression
outcomes of
Lyme disease due to tolerization to such fungal antigens as LYMErix
and the HIV
antigens gp120 and gp41 are likely to be the cause of all the New
Great Imitator
Neurological outcomes, such as Multiple Sclerosis, ALS, and the like,
through immune
suppression, the anchoring of the auto-kill kinases, and the
activation of latent
viral and infections and allowing for all kinds of opportunistic
infections, such
as mycoplasmal infections in the blood.
Amazingly, if one searches the patent database, one would find a
Fauci patent
for the treatment of immune suppression outcomes of bacterial, viral,
and fungal
infections:
http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO1&Sect2=HITOFF&d=PALL&p=1&u=%2Fnetahtml%2FPTO%2Fsrchnum.htm&r=1&f=G&l=50&s1=5,696,079.PN.&OS=PN/5,696,079&RS=PN/5,696,079
FIELD OF THE INVENTION
The present invention pertains to a method for activating the
immune system
of a patient by intermittently administering interleukin-2 (IL-2) to
that patient.
Such administration of IL-2 can optionally be combined with other
therapies, such
as anti-retroviral, anti-bacterial or anti-fungal therapies, suitable
for treatment
of the patient's condition. This invention also relates to an approach
to gene
therapy that entails administering IL-2 to a patient so as to
facilitate in situ
lymphocyte transduction by a retroviral vector also administered to
the patient.
BACKGROUND OF THE INVENTION
Attempts at immune activation and restoration in the past have
utilized bone
marrow transplantation or lymphocyte transfers (H. C. Lane et al.,
Ann. Internal
Med. 113:512-19 (1990)), immunomodulating agents such as immuthiol (J.
M. Lang et
al., Lancet 24:702-06 (1988)) or isoprinosine (C. Pedersen et al., N.
Engl. J. Med.
322: 1757-63 (1990)), and recombinant cytokines such as interferon
alpha (IFN-.alpha.)
and IL-2. H. C. Lane et al., Ann. Intern. Med. 112:805-11 (1990); H.
C. Lane et
al., J. Biol. Response Mod. 3, 512-16 (1984); D. H. Schwartz et al.,
J. Acquir.
Immune Defic. Syndr. 4, 11-23 (1991); P. Mazza et al., Eur. J.
Haematol. 49:1-6
(1992); H. W. Murray et al., Am. J. Med. 93:234 (1992); H. Teppler et
al., J. Infect.
Dis. 167:291-98 (1993); P. Volberding et al., AIDS Res. Hum.
Retroviruses 3:115-24
(1987). These studies have resulted in minimal or only transient
immune system restoration.
The use of biologic response modifiers in general, and of IL-2 in
particular,
is an active area of clinical research. Interleukin-2 is a T cell-
derived lymphokine
with a number of immunomodulating effects including activation, as
well as induction
of proliferation and differentiation, of both T and B lymphocytes. K.
A. Smith,
Science 140:1169-76 (1988). Exogenous IL-2 has been shown in vitro to
increase the
depressed natural killer cell activity and cytomegalovirus-specific
cytotoxicity
of peripheral blood mononuclear cells from patients with AIDS, as well
as to increase
IFN-.lambda. production by lymphocytes from patients with AIDS. A. H.
Rook et al.,
J. Clin. Invest. 72:398-403 (1983); H. W. Murray et al., loc. cit.
76:1959-64 (1985).
It's a patented treatment for the immune suppression outcomes of
Lyme disease,
which is a condition simultaneously denied by the head of the National
Institute
of Allergy and Infectious Diseases- who owns this patent.
"It is an indescribable experience knowing that what you are doing
will
have an impact on the lives... of millions of people." --Anthony Fauci,
1993
Yeah, thanks, Ton'. It's been fabulous.
CHAPTER 12, CROOKS DEPLOY the MUMBO-JUMBO DUMBOS Deploying
scientifically invalid
psychiatry is a crime
http://www.ourladyswarriors.org/prayer/michael.htm
Saint Michael the Archangel,
defend us in battle.
Be our protection against the wickedness and snares of the
devil.
May God rebuke him, we humbly pray;
and do Thou, O Prince of the Heavenly Host -
by the Divine Power of God -
cast into hell, satan and all the evil spirits,
who roam throughout the world seeking the ruin of souls.
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