COX-2 inhibitors and CP
Randall Couch
for some time.
There was recently an article in The New Yorker (titled "Super Aspirin")
about a new class of anti-inflammatories under development called COX-2
inhibitors. The spur for their development was arthritis. The article
reported that the first of these drugs, called "celebra," is dramatically
more effective than any current NSAID for osteoarthritis, and that so far,
despite concentrated looking, no side effects of any kind have been
discovered. Second-generation members of the class are already under
development. The article reported some hopeful speculation that long-term
treatment with this class of drug might actually permit some natural
repair of arthritic joints--some reversal of the process, not just
analgesis. The article also mentioned that the chemical type (a prostaglandin,
if I remember correctly) suppressed by this drug also plays a role in
other inflammatory diseases and in conditions such as Alzheimer's.
Naturally I wondered whether this type of drug might have application in
CP, if only in symptom control. My own mild symptoms are helped by
low dosages of alpha blockers, but the side effects are undesirable.
I'd appreciate it if any knowledgeable researchers or physicians could comment
on this possibility. I think I recall that the article said the drug was a
little less than two years away from market.
Thanks,
-RC
Wayde Wyatt
Randall Couch wrote in message ...
>Naturally I wondered whether this type of drug might have application in
>CP, if only in symptom control. My own mild symptoms are helped by
>low dosages of alpha blockers, but the side effects are undesirable.
Is the alpha blocker you're refering to Cadura? My Dr. gave me an Rx for
it, but the side effects are so aweful, I thought I'd see if anyone else was
having success with it before continuing. If so, what dosage are you using
and how long do you take if before your CP symptoms go away?
Thanks so much,
Wayde