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sha...@my-deja.com schrieb:
Ken H.
<sha...@my-deja.com> wrote in message news:7okkv5$2bq$1...@nnrp1.deja.com...
Does anybody know how much one should take have an effect on cholesteral?
I've been taking 2-3g/day for months. Why do you suggest medical
supervision?
"sedated" <[No Spam]@worldnet.att.net ; replace [No Spam] with sedated
e-mail> > wrote in message <7p008o$rak$1...@bgtnsc02.worldnet.att.net>...
>Ken H. <k...@h.com> wrote in message
>news:7oleen$cau$1...@nntp2.atl.mindspring.net...
>> You need to take it in
>> higher doses under a doctors care who has experience using niacin at
>>higher doses.
>I've been taking 2-3g/day for months. Why do you suggest medical
>supervision?
Taking a lot of niacin can cause temporary liver damage.
The best way to avoid the problem is to increase your dosage of niacin very
gradually. Taking some of it in the form of No Flush Niacin, helps too.
Always take niacin with a meal.
Personally, I would not take more than 1.5 grams of niacin a day as the risk
of liver damage is too great.
Pantehine (NOT patothenic acid), an expensive form of B-5, is also proven
to reduce cholesterol.
John Gohde, Health Nag
http://www.quackwatch.com/
Anyone genuinely interested in diet, nutrition, and nutritional
supplements should take a strong stand against Nutrition Quackery,
Food Faddism, and Nutritional Supplements Quackery anywhere
they see it. If you don't, no one will take your interests seriously.
I thought the time-released variety of niacin was the only "version" that
caused liver damage?
Ken H.
sedated wrote:
>
> I've been taking 2-3g/day for months. Why do you suggest medical
> supervision?
There is a significant probability you liver could be fried with chronic
exposure to high niacin doses.
Some individuals are less tolerant than others.
Bill
>I thought the time-released variety of niacin was the only "version" that
>caused liver damage?
Immediate release niacin can also cause liver damage. The time
release variety implicated is more often. There is a hybred variety,
Niaspam, that seems to combine the best of each type, but it also is
not free from possible liver side effects.
>> Taking a lot of niacin can cause temporary liver damage.
>>
>> The best way to avoid the problem is to increase your dosage of niacin
>very
>> gradually. Taking some of it in the form of No Flush Niacin, helps too.
>> Always take niacin with a meal.
>>
>> Personally, I would not take more than 1.5 grams of niacin a day as the
>risk
>> of liver damage is too great.
>>
>> Pantehine (NOT patothenic acid), an expensive form of B-5, is also
proven
>> to reduce cholesterol.
>I thought the time-released variety of niacin was the only "version" that
>caused liver damage?
If you were to read the studies that use IR niacin to control cholesterol
they always talk about people who had to drop out of the study due to liver
problems. The higher the dosage the more likely people had to drop out,
either immediately or before the study was over.
Usually 1.5 grams is the starting point of these studies with 3 grams the
ending point. There are people who can not take even 1.5 grams. However, I
do believe that starting very gradually will prevent most of these problems.
With a proper diet, 1.5 grams should take you down to about a total
cholesterol level of about 165. If you cholesterol level is shy high and
your TC is out of sight you should be taken prescription cholesterol
medicine anyway, at least until you get your diet under control.
<19990814131358...@ngol06.aol.com>...
>x-no-archive:yes
>
>
>In article <7p3s7i$m2i$2...@bgtnsc02.worldnet.att.net>, "John Gohde"
><johnh...@worldnet.att.net> writes:
>
>>
>>With a proper diet, 1.5 grams should take you down to about a total
>>cholesterol level of about 165. If you cholesterol level is shy high and
>>your TC is out of sight you should be taken prescription cholesterol
>>medicine anyway, at least until you get your diet under control.
>Are you actually prescribing treatment now?
When somebody replies to my posts, I general post a reply.
I wrote precisely, what I wrote.
Nobody replies to your posts because you are obviously mentally unbalanced.
I have deleted the rest of your dribble and threw it out with the trash
where it belongs.
You are another one of those negative people, WHO will NOT ruin my day.
>>Nobody replies to your posts because you are obviously mentally
unbalanced.
>>I have deleted the rest of your dribble and threw it out with the trash
>>where it belongs.
>Maybe no one replies because I just prevent info, rather than tell folks
what
>to do and to think. Not much to discuss when info is plain, well
documented
>and coherently presented.
Anybody who wrote what you wrote to the context of my reply to a person
seeking specific information on Niacin, shows me that you are indeed
mentally unbalanced.
Perhaps, your being female also explains it?
>In article <7p52cs$p4d$1...@bgtnsc01.worldnet.att.net>, "John Gohde"
><johnh...@worldnet.att.net> writes:
>>Anybody who wrote what you wrote to the context of my reply to a person
>>seeking specific information on Niacin, shows me that you are indeed
>>mentally unbalanced.
>>Perhaps, your being female also explains it?
>Yeah, I'm sure you're right; that must be the problem.
Being, unable to control ones own emotions is a Character Flaw.
Animals are ruled by their passions.
You have my condolences.
Sort it out John
Hamish
John Gohde wrote in message <7p52cs$p4d$1...@bgtnsc01.worldnet.att.net>...
>Susan Fein wrote in message
><19990814195430...@ngol06.aol.com>...
>
>>>Nobody replies to your posts because you are obviously mentally
>unbalanced.
>>>I have deleted the rest of your dribble and threw it out with the trash
>>>where it belongs.
>
>>Maybe no one replies because I just prevent info, rather than tell folks
>what
>>to do and to think. Not much to discuss when info is plain, well
>documented
>>and coherently presented.
>
>
>Anybody who wrote what you wrote to the context of my reply to a person
>seeking specific information on Niacin, shows me that you are indeed
>mentally unbalanced.
>
>Perhaps, your being female also explains it?
>
>Wow, even though I may not have much time for Susan that is a pretty low
>blow.
>
>Sort it out John
Sorry, But I don't think that lack of self-control is any excuse to excuse
another person from making personal attacks against you just because that
person had
a bad day.
All I did was answer a specific question about Niacin. That
person by the way, could have been risking serious liver damage. I should
not have to put up with this king of garbage from Susan, or anyone else,
under any circumstances.
>John,
>Your initial post re: niacin's ability to bring cholesterol to 165 is
>so overly broad that it is nonsense. Now you start attacking people
>who disagree, and blather about gender? If you had exhibited a sense
>of humor in your many other posts, I would understand a "tongue in
>check" comment, but you haven't. Get a grip.
Excuse Me, But I was replying to: sedated <[No Spam]@worldnet.att.net
Therefore, I don't care about your opinion.
Being Femaile is NO EXCUSE for being Mental!!!
>I thought the time-released variety of niacin was the only "version" that
>caused liver damage?
There is a lot of published research on the subject, unfortunately most of
it has no abstracts available. But, I have provide a few abstracts as
follows.
We suggest that nicotinic acid was the cause of his liver disease,
A 46-year-old man began taking nicotinic acid, 3 g daily, for
hypercholesterolemia. A month later, he developed clinical and biochemical
evidence of modest hepatocellular injury, and therapy was stopped. It was
restarted 6 weeks later, and 10 weeks after that, the patient presented with
fulminant hepatic failure, which resolved rapidly after cessation of
nicotinic acid therapy. We suggest that nicotinic acid was the cause of his
liver disease, that this case is of particular note because of the rather
short period of therapy before the onset of liver injury and the severity of
the hepatic failure, and that the probable increased use of nicotinic acid
for serum cholesterol control makes it especially important for physicians
and their patients to be alert to the signs of hepatotoxicity.
-----------------------
TITLE: Nicotinic acid-induced fulminant hepatic failure.
AUTHORS: Clementz GL; Holmes AW
SOURCE: J Clin Gastroenterol 1987 Oct;9(5):582-4
CITATION IDS: PMID: 3680913 UI: 88060337
The IR niacin is preferred for the management of hypercholesterolemia but
can also cause significant adverse effects and should be given only to
patients who can be carefully monitored by experienced health professionals.
--------------------------------
TITLE: A comparison of the efficacy and toxic effects of sustained- vs
immediate-release niacin in hypercholesterolemic patients [see comments]
AUTHORS: McKenney JM; Proctor JD; Harris S; Chinchili VM
SOURCE: JAMA 1994 Mar 2;271(9):672-7
CITATION IDS: PMID: 8309029 UI: 94142085
A 61-year-old white man with hypercholesterolemia complained of marked
pruritus and became jaundiced after taking 3.0 g of crystalline nicotinic
acid daily for 13 months.
CONCLUSIONS: Nicotinic acid-induced cholestatic jaundice may not be as rare
as previously thought, and physicians should observe their patients for it.
------------------------
TITLE: Intrahepatic cholestasis during nicotinic acid therapy.
AUTHORS: Patel SD; Taylor HC
SOURCE: Cleve Clin J Med 1994 Jan-Feb;61(1):70-5; quiz 80-2
CITATION IDS: PMID: 8124850 UI: 94170523
We report a case of severe liver injury occurring on two occasions in a
patient ingesting large doses of nicotinic acid. The liver architecture was
markedly distorted, with both massive and submassive lobular collapse and
marked cholestasis. Complete resolution of biochemical and histologic
abnormalities occurred after withdrawal of these drugs.
-------------------------------------
TITLE: Niacin hepatitis.
AUTHORS: Patterson DJ; Dew EW; Gyorkey F; Graham DY
SOURCE: South Med J 1983 Feb;76(2):239-41
CITATION IDS: PMID: 6823602 UI: 83120264
PARSHURAM wrote in message <19990809000033...@ng-fq1.aol.com>...
Kathy