Osteoporosis

[Anita]

Was just diagnosed with "moderate to extensive osteoporosis". Now, don't
mean to be paranoid but, can this be related? Reason I ask is because I'm
only 36, gosh darnit all.

Anita (stomping feet)
Ps: not sure if I sent this the right way the first time, so sorry if there
any repeats!

[Art Doherty]

Here are four MEDLINE abstracts on Lyme disease and osteoporosis:

TITLE: [In Process Citation]
VERNACULAR TITLE:
Opis przypadku boreliozy.
AUTHORS: Hrycek A; Oslawska-Dierzega A; Kossowski M
Kasztura W
AUTHOR AFFILIATION:
II Katedry i Kliniki Chorob Wewnetrznych Slaskiej Akademii Medycznej w
Katowicach.
ABSTRACT:
A male patient aged 38 was complaining from severe musculo-arthral
pains and high body temperature of 39 degrees C. He was admitted to
the clinical hospital after long and detailed diagnostic
procedures--conducted during previous hospitalization, which focused
on Plasmocytoma. Serological examinations relating to Lyme disease
were undertaken in the clinical hospital and the results appeared
positive. The patient received Vibramicin for a prolonged treatment
lasting 30 days. Radiological findings showed distraction in both hip
joints (especially the right one), with areas of bone erosion, severe
osteoporosis and calcifications in periarthral soft tissues. After
pharmacological treatment the body temperature normalized and the
pain became less severe. The state of the patient's health improved
from subjective and objective point of view.
NLM PUBMED CIT. ID: 10806930 NLM CIT. ID: 20266893
SOURCE: Wiad Lek 2000;53(1-2):104-8
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids10806930=&dopt=Abstract

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TITLE: [Rheumatic manifestations in Lyme borreliosis: personal
experience in patients with oligoarthritis of "unknown" origin]
AUTHORS: Kerimovic Dj; Mladenovic V; Dmitrovic R; Lako B
Kecman-Prunic B; Kovacevic M
ABSTRACT:
Lyme borreliosis is an infectious illness caused by the spirochete
Borrelia burgdorferi and is transmitted by tick vectors. A
prospective study was performed from January 1990, to investigate
whether Lyme arthritis might have been undetected among patients with
(unclassified arthritis) oligoarthritis of "unknown "
aetiology. 210 patients were tested for antibodies to Borrelia
burgdorferi: 82 patients with oligoarthritis of "unknown "
aetiology; 52 patients with Reiter's syndrome; 20 patients with
seronegative, B-27 positive oligoarthritis and 56 controls.
Serological testing for Borrelia burgdorferi was performed by
indirect immunofluorescence assay. The occurrence of positive
antibodies (1:80) in 11 (13.4%) patients with arthritis of
"unknown " aetiology was significantly different from the
combined control group (1.6%) (p < 0.05). Four out of 11 patients
remembered a tick bite, two out of 11 patients developed erythema
migrans after 3 to 10 days. Six weeks later 2 patients developed
oligoarthritis and one patient after a month. In the remaining 8
patients arthritis was the first sign of the disease. Knees were most
commonly affected (90%). Radiographic abnormalities (osteoporosis,
soft tissue swelling) were noted in 3 patients. The synovial fluid
findings were typical for inflammatory arthritides in 6 patients. The
diagnosis of Lyme borreliosis was made according to following data:
origin from an area endemic for Lyme borreliosis, tick bite, erythema
migrans, significant levels of the antibodies to the Borrelia
burgdorferi and oligoarthritis. It can be concluded that arthritis
may be the main manifestation of Borrelia burgdorferi infection.
NLM PUBMED CIT. ID: 8262407 NLM CIT. ID: 94085814
SOURCE: Glas Srp Akad Nauka [Med] 1993;(43):195-202
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8262407&dopt=Abstract

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TITLE: Lyme arthritis: clinical features, serological, and radiographic
findings of cases in Germany.
AUTHORS: Herzer P; Wilske B; Preac-Mursic V; Schierz G
Schattenkirchner M; Zollner N
ABSTRACT:
The clinical manifestations, serological data, and radiographic
findings of ten cases of Lyme arthritis in Germany are summarized.
Qualitative assessment shows that the characteristics of the disease
in Germany do not differ fundamentally from those reported in the
USA. However, since a serological test for antibodies to the
causative spirochete is now available, the great variety of the
clinical features of Lyme arthritis can be described more precisely.
The cases of chronic Lyme arthritis without prior erythema chronicum
migrans, hitherto the most important diagnostic hallmark of the
disease, may have been underestimated. One of the cases reported
provides evidence that the disease was transmitted via a fly bite.
Radiographic abnormalities consisting of marked juxta-articular
osteoporosis and osseous erosions were found in two patients with
chronic arthritis. Three patients were treated with high-dose
intravenous penicillin, two did not respond to the therapy.
NLM PUBMED CIT. ID: 3702279 NLM CIT. ID: 86201433
SOURCE: Klin Wochenschr 1986 Mar 3;64(5):206-15
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3702279&dopt=Abstract

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TITLE: Lyme arthritis: radiologic findings.
AUTHORS: Lawson JP; Steere AC
ABSTRACT:
Lyme disease is a newly recognized, multi-system disorder that may be
associated with chronic arthritis. Of 25 patients with severe
arthritic manifestations the most frequent radiographic finding was
knee joint effusion. Intra-articular edema was often accompanied by a
continuum of soft-tissue changes involving the infrapatellar fat pad,
periarticular soft tissues, and the entheses, which were sometimes
thickened, calcified, or ossified. Later in the illness, the joints
of some patients showed typical changes of an inflammatory arthritis,
including juxta-articular osteoporosis, cartilage loss, and cortical
or marginal bone erosions. Less commonly, other patients demonstrated
changes more characteristic of degenerative arthritis, including
cartilage loss, subarticular sclerosis, and osteophytosis. Joint
involvement of Lyme disease has similarities to juvenile arthritis
and Reiter syndrome, but can usually be distinguished clinically and
serologically from these entities.
NLM PUBMED CIT. ID: 3964949 NLM CIT. ID: 85064588
SOURCE: Radiology 1985 Jan;154(1):37-43
http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3964949&dopt=Abstract

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The above abstracts were found by the following MEDLINE search link:

MEDLINE - osteoporosis AND Lyme disease - 5 citations found on 26 May 00
http://igm-02.nlm.nih.gov/cgi-bin/IGM_robot.pl?search=Subject=osteoporosis+AND+Subject=lyme+OR+Subject=burgdorferi+OR+Subject=Erythema+Chronicum+Migrans+OR+Subject=borreli*+ixodes+OR+Subject=Erythema+Migrans+NOT+glossitis+OR+Subject=garinii+OR+Subject=afzelii+OR+Subject=neuroborreliosis&datafile=MEDLINE

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For more information on Lyme disease, see:

Lots Of Links On Lyme Disease
http://www.geocities.com/HotSprings/Oasis/6455/lyme-links.html

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Art Doherty
Lompoc, California
doh...@utech.net