Lyme Victims Pay for Polish Chickens' Diseases.
Mort Zuckerman
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Subject: [SpinLyme] Lyme Victims Pay for Polish Chickens' Diseases.
Date: Mar 8, 2010 1:51 PM
"Taken together, we have determined the evolutionary history of a
major new animal pathogen that has undergone rapid avian host
adaptation and intercontinental dissemination. These data provide a
new paradigm for the impact of human activities on the emergence of
animal pathogens."
Jeepers.
IDSA is making Lyme victims pay
for hospitals staff incompetence
over a disease generated by Polish
chickens.
The Queen of America has about
had enough...
http://www.commondreams.org/view/2010/03/08-2
"Calling All Rebels"
========================================
http://www.pnas.org/cgi/pmidlookup?view=long&pmid=19884497
http://www.ncbi.nlm.nih.gov/pubmed/19884497
Recent human-to-poultry host jump, adaptation, and pandemic spread of
Staphylococcus aureus.
Lowder BV, Guinane CM, Ben Zakour NL, Weinert LA, Conway-Morris A,
Cartwright RA, Simpson AJ, Rambaut A, Nübel U, Fitzgerald JR.
The Roslin Institute and Centre for Infectious Diseases, Royal (Dick)
School of Veterinary Studies, Queens Medical Research Institute,
University of Edinburgh, Edinburgh EH8 9YL, Scotland, United Kingdom.
The impact of globalization on the emergence and spread of pathogens
is an important veterinary and public health issue. Staphylococcus
aureus is a notorious human pathogen associated with serious
nosocomial and community-acquired infections. In addition, S. aureus
is a major cause of animal diseases including skeletal infections of
poultry, which are a large economic burden on the global broiler
chicken industry. Here, we provide evidence that the majority of S.
aureus isolates from broiler chickens are the descendants of a single
human-to-poultry host jump that occurred approximately 38 years ago
(range, 30 to 63 years ago) by a subtype of the worldwide human ST5
clonal lineage unique to Poland. In contrast to human subtypes of the
ST5 radiation, which demonstrate strong geographic clustering, the
poultry ST5 clade was distributed in different continents, consistent
with wide dissemination via the global poultry industry distribution
network. The poultry ST5 clade has undergone genetic diversification
from its human progenitor strain by acquisition of novel mobile
genetic elements from an avian-specific accessory gene pool, and by
the inactivation of several proteins important for human disease
pathogenesis. These genetic events have resulted in enhanced
resistance to killing by chicken heterophils, reflecting avian host-
adaptive evolution. Taken together, we have determined the
evolutionary history of a major new animal pathogen that has undergone
rapid avian host adaptation and intercontinental dissemination. These
data provide a new paradigm for the impact of human activities on the
emergence of animal pathogens.
"[Real] scientists are *fiercely* independent. That's the good
news."-- NIH's Top Fool, Anthony Fauci
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