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Every cancer patient enters remission after drug trial, study reveals

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Mr. Wayne

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Jun 23, 2022, 3:37:58 AM6/23/22
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A recent drug trial administered to a handful of cancer patients had the
surprising result of eliminating the disease in every participant
involved.

The study was conducted on 18 rectal cancer patients at Memorial Sloan
Kettering Cancer Center in Manhattan and had a 100 percent success rate,
according to a paper published Sunday in the New England Journal of
Medicine.

“I believe this is the first time this has happened in the history of
cancer,” Dr. Luis A. Diaz Jr, the author of the paper, told the New York
Times.

The drug, dostarlimab, was administered to each patient every 3 weeks for
6 months.

The drug trial was expected to be followed by chemotherapy and surgery, as
is standard, for every participant.

Some patients may have even required surgery leading to bowel and urinary
dysfunction — or be forced to use a colostomy bag due to treatment, the
Times said.

However, since all patients had no evidence of a tumor after taking an
MRI, rectal examination or a biopsy they were spared the agony of
potentially damaging treatment.

“There were a lot of happy tears,” Dr. Andrea Cercek, an oncologist at
Memorial Sloan Kettering Cancer Center told the Times.

In addition to not needing further treatment, there were no instances of a
recurrence of cancer in the patients during follow-up appointments from 6
to 25 months after the trial ended.

One participant, Sascha Roth, told the Times that she planned to move to
Manhattan for chemotherapy and radiation treatment.

Then doctors gave her the good news — the trial worked and she was cancer-
free.

“I told my family,” Roth said. “They didn’t believe me.”

https://nypost.com/2022/06/06/every-cancer-patient-enters-remission-after-
drug-trial/

governo...@gmail.com

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Jun 24, 2022, 1:59:12 AM6/24/22
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On Thu, 23 Jun 2022 07:37:57 -0000 (UTC), "Mr. Wayne"
<ed...@fullerton.edu> wrote:

I read about this a couple of weeks ago. The patients had a very
specific condition, "mismatch repair deficient (dMMR) recurrent or
advanced solid tumors".
https://www.fda.gov/drugs/resources-information-approved-drugs/fda-grants-accelerated-approval-dostarlimab-gxly-dmmr-advanced-solid-tumors

In the article I read, the drug can be modified to target different
kinds of cancers.

Swill
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