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Advancements in Textile Engineering and Applications
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Kay Lie
Aug 5, 2023, 12:01:45 PM8/5/23
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bra underwear, and wrist elastics and fabics that are supersoothing. microfiber baby washcloth supersoft thread technology on elastics and skin touching parts
at currency acceptor machines like ATMs and grocery auto checkouts a slightly higher functionality currency separator and mover could come from the use of piezoelectricts at the deposited currency stack hypervibrating the top, imaged currency item off the top where, from piezojiggling it comes near enough a mover arm or vacuum multiaperture platen to then traverse to the next location, like a currency holding canister. The piezojiggling could be one size fits all, or better, dynamically adjusted to the mass and texture of each THz scanned, or optically scanned, or ultrasound scanned currency object
Its likely already researched but quantum ghost imaging at landmine detection and removal makes sense. Yay Peace.
as a carefully researched ingredient at prenatal vitamins or supplements, could the active molecules at Tiliacora Triandra reduce or prevent fetal alcohol syndrome, there is a paper titled, “Tiliacora triandra, an Anti-Intoxication Plant, Improves Memory Impairment, Neurodegeneration, Cholinergic Function, and Oxidative Stress in Hippocampus of Ethanol Dependence Rats” At that paper Donepezil also reduces some etoh effects, causing about 2-4 multiples higher visual perception of hippocampus neuron density at both TT(2-3 multiples) and Donezepil(3-4 multiples) Wikipedia notes Donezepil, Aricept, has side effects, and these may preclude use during pregnancy. As an alternative, epigenetic modulators with brain area localization peptides could do what TT and Aricept do during pregnancy, benefitting the fetus.
A name similar to genetic yamaka factors causes cytes to dedifferentiatiate to be stem cytes that can then develop at completely different cyte types of plural types, as a longevity product, epigenetically upregulating the human body’s production of yamaka factor gene activity, possibly with crispr gsDNA demethylation causes a greater amount of circulating, regenerating stem cytes, combining that with epigenetic upregulation of p53 tumor supresssor gene could then reduce risk of cancer even though human cytes and tissues were regenerating and proliferating more rapidly, these two things together then are a longevity and youthspan and healthspan heightening technology.
as an epigenetic modulator drug that heightens longevity and wellness, demethylation with crispr gsDNA, acetylation, or methylation that reduces blood pressure is beneficial, and may be single depot molecule dose.
Sundet, at a study of 40,000 Norwegian twins found that birth year caused heitability of IQ to range from a very high .89/.92 to a kower .23/.29 on a 78 monthish cycle, Norway has extensive lifespan length, and healthspan estimates from medical records, among those being cardiovascular wellness and cancer below median occurences, finding out which, if any of those follow the sundet cycle could be utilized to heighten longevity and wellness
I am unaware of a published source of what I call the Sundet cycle, measurements of EM RF of course make sense, but it is possible, even though the physics is peculiar, that some attribute of angle towards the earth or sun that reoccurs about every 78 months could have an effect, as a possible modulator of this cycle, first demonstrate it at microorganisms and daphnia, then find out if raising these in outer space effects their sundet cycles, further research could have mice raised at different geostationary orbits, and novel pole to pole looping orbits, norwegian latitude orbits, and even, using microgravity stability at the habitat, the ability to fertilize and raise the microorganisms or mice vertical perpendicular to the earths surface and geostationary, like a ferris wheel, as well as horizontal to the Earths surface like a plate, as well as diagonal could be tested, notably, if these change the sundet cycle, then different things that shield or focus sundet cycle effect can be tested and possibly found. While I have no clue what these are, the chronically optimistic might find that there is some attribute of frame of reference, or even relativity concerned. Of course the pragmatic might like testing deep underground locations, as well as microorganisms and mice raised on comfortably climate modified 78 month weather balloons or mouse habitat blimps to see if there is a nearness to matter effect. There may be a previous note about how the sundet cycle might be as brief as 1/40th the length interval of 78 months from a lifespan or gestation interval ratio. That suggests breeding, fertilizing, and developing mice to the equivalent of human 18 would be 8 new mice, with parturition of a fresh cohort every 7 days, for 2 1/2 months, testing mouse cognition, cancer, and social attributes once each 8 days through to mouse adulthood, the most rapid procedure being about 2 months of mouse breeding, 20 weeks of observation, with all 16 cohorts receiving at least 8 weeks of observation and testing each. At .64 mice/day and 4 months, divided with 2 that is less than 3800 at $1/day mouse facility fees utilizing an enriched environment. A full lifespan experiment would be better. The actual procedure would be much more to fund the human scientists, and to cover the mouse facility timed provision of fecund mice and sires.
methylation aging clock reset drugs could opt to find any methylations at DNA that occur with living past the 40s that raise blood pressure, then preferentialize resetting those to the persons own epigenetic form, or an even better epigenetic form, this blocks a rise of blood pressure with age, and increases cardiovascular wellness and healthspan
epigenetic clocks, such as methylation clocks or possible acetylation clocks could be be described as to which epigenetic modifications are both logical necessary, and logical sufficient to be associated with being nonalive within 900 days of the epigenetic clock epigenetic location particular form taking on a particular value. This identifies lethal epigenetic variations that can then be addressed with molecules to be reversed and maintained to be at the the life supporting form at humans of all chronological ages. This preclusion of epigenetic clock terminator forms is then a longevity and and likely also healthspan heightening technology, demethylators like crispr gsDNA, methylators like iRNA, and acetylators could all be actual technological forms of this longevity technology
sensationless injection needles, scalpels, and other medical apparatus are described at other notes as utilizing the numbing effect of vibration, particularly piezoelectrictric ultrasonic vibration from having a battery at a syringe, a tiny 1/4 cent alibaba piezoelectric element, and a 1-1/10th cent alibaba disposable zinc air battery to cause numbness at the injection site from vibration. It could even be that this is a plessant sensation, a new alternative technology is to coat the the injector/slicer metal part with picograms or femtograms of opiate peptides or fentanyl dissolved in eutectic liquid metal such as a gallium indium eutectitic alloy that releases just enough of it at the injection site to cause highly localized numbing, nerve receptor blcoker nonopiate peptide blockers could also be used, increasing comfort. a much less valuable technology, but a different one is to use a peltier element, 1/4-/1/10th of am alibaba 10 cent 10 mm square piezoelectric cooling element to cool the injector or scalpel.
There is a physics demonstrator apparatus that looks like a container with holes drilled in the side with a bunch of separate narrow streams of water flowing out the holes at different curves, this looks similar to a paper towel tube with polka dot holes all over it. As a form of injection needle at immunizations this could deliver vaccine to a wider area and volume, promoting a greater immune response, then, piezoelectrically vibrating such a syringe needle the vaccine could spread or stir to a much wider volume of cytosurfaces at the injection site, if each of these is used together then the amount of $ vaccine utilized could be much less, making vaccines cheaper per dose. This could also work with dental anesthesia injections, piezoelectric vibration could also rapidify dental injection site numbness causing topical gel activity
Nernst batteries are previously described at notes, these use the nernst effect where ion amount difference between two things creates an electrical potential, the ions are of the same kind, which makes it different than a dissimilar electronegativity battery, something like a grid of micro tubules, each with a different geometry, having a vacant space at the top continuously evaporate a solvent like water, creating an ion concentration difference which then makes electricity from the nernst effect, online it says, “2 microvolts per kelvin…[at] previously created thermocells which produce 2 microvolts per Kelvin by using a change in pH”, a square 43 units on a side is 1K multiples of 2millivolts, or 2 volts, millimeter sized tubes, cheap like microbubblewrap, that than produce about 2V at a 4.3 cm sided square battery, stacked 11 high they then produce 22 volts. I think the current depends on how rapidly the ion difference is refreshed.
Replacing element C with other elements of the same column of the periodic table is well known, like silicone polymers, I read that there are variations of the melatonin molecule that are more radioprotective then melatonin, replacing some of the C atoms at those molecules could make new radioprotective molecules which could be measured to see if they have longevization effects
wikipedia has a big list of things activated with mtorc1, and rapamycin is likely to cause greater longevitty from inhibiting mtorc1, inhibiting each of those activated things separately could be tested to see if it causes greater longevity as a way of finding new longevity drugs
Tyrosine message passing and activation causes all kinds of things to happen (wikipedia), they could simply test if tyrosine supplementation heightens wellness, and, possibly longevity, some other things like NMN have a more is better effect, they could test tyrosine
schizophrenia is linked to dopamine receptors which have many types, wikipedia says of a different thing, “Another function of VEGFR-1 may be to act as a dummy/decoy receptor” are there any decoy receptors that have aan effect on reducing schizophrenia while maintainining cognitive function
as an artificial sweetener that causes greater wellness, another artificial sweetner that has a glycemic insulin response is blendable with ribose, a sweet sugar that reduces insulin response, “oral or intravenous ribose administration produces a transient, asymptomatic, and dose dependant decrease in plasma blood glucose to a nadir that is reached 30- to 75-minutes post-administration, before returning to baseline levels in approximately 60- to 120-minutes”
I think upregulating ampk is associated with greater longevity, wikipedia, “the ratio of AMP to ATP molecules gets too high, AMPK will become activated. AMPK will go on to inhibit energy consuming pathways such as protein synthesis.” So drugs that just change AMP to ATP ratios could also favor longevity, peptides are a possibility
mtorc1 is inhibited, causing rapamycin like longevity effects from the protein hypoxia inducible factor one alpha (HIF1A), epigenetic modulation, or peptide drugs that do hif1A things could cause the hypoxia longevity benefits while breathing completely normal amounts of Earth air at humans. hibernating hypoxic mammals and deep sea fish live longer from hypoxia
wikipedia mentions a couple dozen mtorc1 activity cascades and activators, as longevity epigenetic molecules,interference iRNA that methylate these epigenetically could be various different new longevity wellness treatments, with single/depot dosing
autophagy is associated with longevity and wellness, blocking things that block autophagy could heighten longevity, wikipedia, “Upon activation, mTORC1 will phosphorylate autophagy-related protein 13 (Atg 13), preventing it from entering the ULK1 kinase complex, which consists of Atg1, Atg17, and Atg101.[61] This prevents the structure from being recruited to the preautophagosomal structure at the plasma membrane, inhibiting autophagy.” all of those are longevity genetic, epigenetic, and medical molecule longevity possibilities
I think it may be previously at notes, but mtorc1 inhibitors that cause longevization could have much longer duration of activity with some of the element c atoms or hydrogens replaced with silicon, germanium, or halogens at these peptides as a long lasting century or multicentury duration longevity drug
x ray fluorescence is used in mineral prospecting, and handheld x ray fluorescence guns are a known technology that robots could utilize, to make prospecting better, do multi separate wavelength x ray spectrometers exist, and would they be even more effective, as simplistitic as it sounds, many imaging technologies work much better with highly cooled sensors, could a nested peltier effect cooler, similar to those used to make near liquid nitrogen temperatures be small, light, and cheap enough to rpovide a few doublings of sensitivity, noting the detector could be at a liquidless thermoslike dewar around it, once cold, it would stay highly sensitized with minimal extra energy, this could possibly also work with human or robot xrf guns, I just read online that peltier elements are used at xrf detectors, Isaac Asimov used to advertise a telescope with a big near spherical reflector near its base, could, perhaps, a robot xrf gun have a bowl shaped x ray retroreflector of say 4/100ths efficiency but 200 multiples greater area than the cooled detector, that would bring 8 times as many echo x rays to the detector heightening effectiveness, if there is such a thing as x ray phosphorescence that might benefit from heightened sensitivity from a sphere reflector, There is an effect where placing a random noise field behind an image causes it to stand out from background more, with greater resolvability, wikipedia does not yet mention a diffuse x ray field accompanying the fluorescence making x ray as a way to generate emerging resolution at an xrf sample, such as at mineral prospecting
D1 specialized neurons with dopamine receptors at particular brain areas like the striatum respond to antipsychotic drugs, using localization moieties or peptides, research drugs that cause those striatum D1 and D2 neurons to have sustained activity, excluding the antipsychotic could then leave the rest of the neurons and regions of the brain at schizophrenics and lab animals to make their effect, if any, on schizophrenia, creating a more functional map of where antipsychotics reduce dopamine activity to reduce schizophrenia, that could be associated with particular symptoms, like audo-like or visual hallucinations, making new molecules with localization to the freshly mapped areas able to treat particular symptoms of schizophrenia,
It is possible dishwashers could air dry faster with coanda air entrainment fans similar to the dyson bladeless fan
at food crops, some flavor neutral version of soapwort, as either a new molecule made at the plant, or placed with the plant at soaking, could cause them to use lesss soak time or preparation time, saving labor, like beans or tubers that soak 20-40 minutes rather than 11 hours
A person mentioned at Bill Gates’ online blog has developed a bean variety/varieties that have just 7% of the presoak and prep time of regular beans, saving fuel, expense, and effort at the developing world, that brings up the possibility of doing similar things at a variety of other foods, it is possible the genetics of hulls, root bark, and seed coatings could be modified or bred to be much thinner or more porous to have this rapid preparation effect. Also, at a variety of tubers and root crops a tuber/potato peeler that has an intrinsically curved shape, that is say 11% longer could reduce food wastage 2-4%, and reduce prep time 8-11%. As another fuel and expense reducing technology, a cutting board, or even cheaper cutting mat could have a stripey reticle on it that guides slicing the peeled tubers to be them smallest delicious size and shape for least fuel use and preparation time, so say a 4 cm cube becomes a 2 cm cube, to make it so the amount of slicing remains constant or decreases, the cutting knife could have two linear spaced blades, say 2 cm apart, better alloys, or newer more affordable forms of laser peening could make the two blades 2-7 times thinner, making cutting as easy, or easier than a single bladed knife, at the entire world, food processors, sometimes similar to cuisinart appliances could be reengineered to reduce prep times and food wastage
semiconductor lasers that do laser peening, mach piezoelectric, transparency grating, metamaterial concentrator funnel, cooling channels at stripey laser flats with fluid between polygons
semiconductor lasers that can cut multicm metal plate are published as of 2023AD, these may be sufficient to do laser peening, even more value effective semiconductor lasers could be made with variations on those, or completely new, cheaper semiconductor lasers, it is possible that the laser peening shockwave moves either at the speed of sound, or faster, putting a piezoelectric vibrator that can move at the speed of speed of sound or higher, and vibrating the workpiece at a mach number could cause the combined velocity of the shockwave to be higher force, making less powerful lasers able to do laser peening, zooming the work piece on a vibrating holder moving towards the laser pulse combines with the shockwave directional motion to velocitize the shockwave to double its velocity, or double its distance, also, the laser could have gratings that cause metal to be much more transparent, which then at actual grooved or tesselated gratings on a semiconductor active layer cause higher semiconductor (rather than metal) transparency reducing warmth build up and heightening efficiency, thinking of a tesselation of laser diodes, like an array, the spaces between the diodes could have channels between them with an immersive fluid between them, or a liquid metal and insulator side layer for heat removal, another possible enhancement is using say a published 100K concentrator optical metamaterial with open areas between the tesselated polygons to take an ordinary 12W/40$ semiconductor laser diode and, with an array of 84 of those make 1KW of laser energy, metamaterial concentrated to a million watts at a narrow beam output that then is concentrated with other optics to make laser peening Watt intensity pulses for about $3700 of semiconductor laser diode material
tiny MEMS accelerometers record minute personal deviations of wobble at a riding bicyclist that are possibly unique to each person. A locator tag on the bike could tell not only where it was, but if a different than usual person was riding it, this could be used to track missing bicycles, as well as diagnose wellness variations at persons using the bicycle, or other exercise technology, to inform them of wellness change,
as a longevity technology finding epigenetic modulators that reduce or block calcification, such as calcification of the pineal gland as well as arteries could cause continued high production of melatonin from the pineal gland and reduce blood pressure from atrtery flexibility throughout living, other drugs are also possible
at published material, just changing peptides to be halogenated, without specific halogenation of particular peptides causes 1.5 multiples greater dose potency, possibly previously written is halogenating specific more electronegative amino acids at peptides such as longevity peptides at particular molecule locations to enhance function, ethynlization of particular, especially electropositive peptides is also possible to enhance the effectiveness of peptide drugs
people, previous to using rapamycin or other longevity molecules could get a cheek swab or nonfluoridated toothbrushing saliva sample to get a saliva or blood sample, which could then be compared to the lab results after they had been taking rapamycin or other molecules for a while, perhaps some of these molecules will also be found to have epigenetic benefit
noting that halogenation of peptides heightens their dose potency 1.5 times, it is possible that halogenation of nucleotides like RNA like at iRNA drugs and iRNA epigenetic modulators could heighten their dose potency as well.
resveratrol has some published data as a longevization molecule, with three OH groups it may have greater benefit with ethynylization of haologenation or dimerization
UV tanning beds may be associated with enhanced mood, and are published as associated with enhanced sleep quality, I do not know if this goes all the way to euphoria or not, duplicating that, without photoaging is beneficial with molecules, as another technology a semiconductor UV LED pad appliable to the buttocks or stomach could cause mood enhancement from the tanning bed effect without photoaging at the face and hands, it could also work on the thighs
possibly there is some way to heighten emulsifier output at all meals, heightening lipid soluble vitamin and other beneficial molecule absorption, wikipedia says, “lipid-soluble nutrient. This process in the human body involves secretion into the small intestine of pancreatic enzymes and bile, which facilitates emulsification and micelle formation required for absorption of lipophilic substances.[47] Food intake (and the presence of lipids) stimulates bodily biliary excretion of bile acids and greatly enhances absorption”
2023AD aging may have caused greater contrast agent like effect on IQ, with higher IQ being more traceable to brain areas, neuron types, and genetics among the particularly old at 2023AD, that makes it possibly easier to find the beneficial and mass inducible genetics that cause higher IQ at persons of all ages among the much older 2023AD persons such as 80 year olds with high IQ
I saw a blonde woman with large nude breasts on Quora and urged her to post more attractive, sexy images, “Thanks for posting, I hope you are a natural blonde, and you and a friend got to have sex or masturbate while taking the image to make it extra sexy. You make me start to get hard. So if you you like delighting people that like breasts and getting guys erect Keep posting!” I also wrote, “Glad to see you sharing your sex pleasure with another at the animated gif. I hope you came, and even had a rememberable orgasm, I only remember about one orgasm I ever had, it would be a good thing to learn to be able to do. I can remember some sex movements and percussions though a little. Glad you are a hotwife and get to be with all the men and women you want.” at another of her posts
a person wrote about photons as a math physics thing, and I wrote, “can a photon of a full wavelength, which would usually be a frequency but is now different, then be a unitary event as a soliton, or the opposite of a soliton, a hyperabsorbable non trigonometric wave?
I’m opposed the the antinausea drug scopalamine as it is used among scientists to induce amnesia in lab mammals, and the thought of recreational travelers forgetting their voyages seems nonoptimal, noting that it is possible that the receptors that scopalamine functions on, at the particularly very specific brain and neuron localizations possible with aptamer peptides could cause an antinausea effect while permitting full remembering capability.
wikipedia talk page comment, “== Unless the Noether theorem is wrong it would be great to have a version of this article at simple.wikipedia.org ==
I wanted to comprehend the theorem while being kind of unsophisticated. a simple wikipedia article could be created about Noether's theorem could be created right here: https://simple.wikipedia.org/w/index.php?title=Noether%27s_theorem&action=edit&redlink=1
I'm clueless, but it seems like it might be wrong based on what are described at wikipedia as time crystals, as well as even possibly turing machines, and any simple motional computing device”
the beneficial to giure out heritability cycle published at a paper written Sundet, a study of norwegian twins and IQ, could be approached to see if there is a sundet cycle with plants, video sorting of seeds, like peas, or leaf variability shapes, could find out if plants have the same .29-.89 heritability of some characteristics based just on what year or month they are seeded, planted, sprouted, measured, if the sundet cycle can be found using software learning imaging of seeds or leaves genetic heitability amount (are they smooth peas, or very high heritability cycle interval smooth peas) plants could then be usilized at outser space to find out where the sundet cycle comes from.
The enthynyl group may be what causes 200 times less first pass hepatic metabolism at the liver of ethynyl estradiol, perhaps ethynylizing rapamycin would increase plasma life and dose postency as well as a longevity drug.
epigenetic modulation is published as reversing aging, with just methylation factors, it makes sense and has likely occured to many others that the 5-7 different kinds of epigenetic modulation could each have their own rejuvenation epigenetic modulator group, ubiquination and acetylaion are two others i have heard of, “continuously expressing only OSK, leaving out the oncogene c-MYC [7, 8]. In the optic nerve, for example, expression of a three Yamanaka factor combination safely resets DNA methylomes and gene expression patterns, improving vision in old and glaucomatous mice via a largely obscure mechanism that requires TET DNA demethylases [8]. Numerous tissues, including brain tissue, kidney, and muscle, have now been reprogrammed without causing cancer [7, 8, 22, 24, 25]. In fact, expression of OSK throughout the entire body of mice extends their lifespan [26]. Together, these results are consistent with the existence of a “back-up copy” of a youthful epigenome”
Notably the OSK epigenetic modulator group is just published as doing age reversal on fibroblasts, OSK and others tested on a variety of other tissue cytes, and whole mice makes sense, the paper suggests whole mice, neurons, cardiomycytes, vascular epithelia and artery cytes, islet cytes, liver cytes, lung cytes, and mitochondria/mtDNA and the cytes most aged at supercentenarians would be beneficial, it is possible three of the tested ccombo epigenetic modulators that are already drugs, parnate(tranylcypromine), an antidepressant, valproic acid, and forksolin could be looked up to see if they are previously published at having epigentic benefit to other cyte tpes, as well as the the other numbered research molecules, valproic acid, parnate and forskolin are published as neuron beneficial, notably as epigenetic modulators they would be taken for just a/few 72 hour occurences per decade, and not as continued doses, entertainingly, a houseplant and decorative plant or tree, and agricultural perennial could be tested with the 2023AD published epigenetic youthful rejuvenation OSK, or even OSK ingredient group as a single epigenetic modulator photosynthetic organism rejuvenator
wikipedia, “Galectin-8 controls mTOR causing its inactivation and dissociation from damaged lysosomes” more of that protein could have longevization effects, as a gene therapy, or beneficial allele variant
Beneficial breathable gas short peptide longevity technology, a short longevity peptide like 4 amino acid AEDG, or two amino acid epithalon could have its hydrogens replaced with longer alkanes, where the alkanes are short halogenated chlorofluorocarbon branches molecules like the breathable halothane anesthetic molecules, a sufficient number od these halothanes replacing hydrogens at peptides could make the peptide have an inhalable gas form at some warmth less than 30 degrees C, this is also true for synthetic amino acid versionions of AEDG epithalon and two amino acid thymalin peptide that have even less mass with full longevization and healthspan benefitting activity. It is even possible that an aimno acid form with a hydroxrl and amino group with a glycine or alanine like polyhydrocarbon could have the polyhardrocarbon be replaced with a polyhalogenated halothane like C atom sequence that has surplus lift to gaseous form that is shared at the entire amino acid sequence making it breathable as a form of new drug dosing of peptide drugs, particularly longevity drugs, it is also possible an inhalebale form of MDMA is possible with similar halothanation of hydrogen locations.
As a possible disease reducing mosquito or tsetse fly volatile attractant, hlogenated, or halothaned hydrogen replacement or methyl group replacement could be used on insect trap attractants that lure malaria and other illness mosquitos and flies to insecticide
CES2 gene product could be beneficial at an enhanced human genome, the internet says, “role of CES2, the researchers genetically engineered mice to overexpress CES2 in their livers and found that the protein improved overall metabolic health. Mice lost weight and had greater endurance and better glucose tolerance than non-genetically engineered mice. The CES2-overexpressing mice could also run faster and for a longer time than their non-genetically engineered counterparts.”
au automated produce produce and fruit harvesters including flying drone fruit and produce harvesters lasers could actively resurface the fruit contact gripping surface several times per day, optimizing contact adhesiveness and structure shape, pulsing dirt or water or gunk off, making it so the fruit and produce contacting surfaces had maintened freshnesss and successfullness, high qualty image recognition could aim the lasers at just the fruit and produce contact touch elements omitting lasers being beamed anywhere ner other items or people, it is also possible that pelitier elements coud condense water from the ir on a cool surface and then rinse or wash autonomomous robots parts and suufrace contact areas.
an artificial sweetener that might reduce glycemic response, compared with some 2022AD atificial sweeteners published as producing averse glycemic response, there is the sweetness of cinnamon bark, cinnamon extract capsules are advertised as reducing glycemic response, it is possible there is a cinnomon based molecule that tastes sweet, while reducing deleterious glycemic response
genetics may be associated with both dental beauty as well as resistance to tooth decay, epigenetic modulators could reduce tooth decay and heighten the beauty of developing teeth, iRNA methylation, and crispr gsDNNA demethylation are possible technologies, as could be new acetylators.
breast implant injected gel component miniblobs could be responsive to high magnetic fields, maing them externally steerable for most beautiful placement
Flavorless or pleasantly flavored nutrient such as physiologically available Fe, other elements, vitamins, and beneficial phytochemicals and other beneficial molecules are producible with microencapsulation of the anemia and birth defect and schizophrenia preventing Fe supplement and other supplements, that makes it such that at the tobgue and saliva there is an absence of Fe flavor, or other supplement flavor from the microencapsulation coating lasting two hours at saliva, with the two hour duration precluding the generation of an aftertaste, while the microencapsulation material is very rapidly dissolving at stomach pH, or also metabolized with stomach enzymes, one very very affordable possibility is custom molecular mass starches and glucose polymers as microencapsulation coatings that preclude Fe and other supplement flavor perception, that absence of flavor then favors supplementing a wider variety of foods with Fe and other supplements
could reactive phosphotidylizing phospholipids not attached to anything as reactive groups then attatch to a variety of things at the body, not yet studied, that then heighten wellnesss, heighten longevity, or treat or cure illness, this is kind of a phospholipids turning down imuunoreactivity on particular things to provide benefit, or turning down immunoreactivity to many things generically to ceate benefit,
A published longevizing gene, “a centenarian-enriched intronic variant residing in a cell-type specific enhancer in SMAD3, a critical receptor-regulated TGF- β signal transducer, was identified. This non-coding SMAD3 variant (rs8040709) altered binding of ELK1, a member of the ETS family of transcription factor important for enhancer activity in certain cell types, resulting in reduced SMAD3 expression. Analysis of the variant in cell types derived from gene edited iPSCs demonstrated the variant reduced SMAD3 expression, senescence and inflammation in endothelial cells. In addition, heterozygosity in SMAD3 improved healthspan and reduced senescence in the Ercc1-/Δ progeroid mouse model of accelerated aging. Taken together, these experiments demonstrate that variants in a cell type specific enhancer of SMAD3 resulted in reduced expression, senescence and inflammation and contributes to human longevity. Thus, SMAD3 represents a validated targeted for drug development for extending human healthspan.”
photonic or acoustiv forms that have physics resonace physical motion which jiggles them so much they cease working, could be used on the mitochondria or other organelles of nerve cetyes at various locations of the body or the cns to very greatly reduce atp energy production that is used to power ant aversive sensation, or any nociception nerve or other cyte, precluding the production of any aversive stimulus, nociception, or discomfort such as a nerve cytes and tissues at arthritic tissues then having arthritis sensation turned off. mitochondria at possibly multihundred nanometer to micrometer size have photonic as well as acoustic resonce frequency wavelengths at physics resonance, those resonance wavelengths could be meamed into cytes and tissues, and body structures and organs, or, different than a beam transmitted as a field effect, it is possible a wide range of nerve and other cyte effects can be caused from resonantly modulating mitochondrial activity, ranging from rapid anesthesia effects, to preclusion of sensation effects
those microthin layers on air conditioer radiators, if made out of some other metal, and semiconductor laser peened to be 14-19 stronger, or greater at their strength could be used at vehicle surfaces and bumpers to absorb collision force with minimal size, mass/weight, and vehicle styling compromise. like a multileaved roller embossed box beam tesselation that gets laser peened. This benefits people from making a bumper that might have previously been a 5 mph bumper actually be a 80-90mph force dissipation bumper saving lives during collisions it also makes a 1/2 cm side of vehicle side collision bumper be able to be as effective a bumper as, possibly a 14-19 multiples thicker 9cm thick collapsible metal plate bumper. These could also be used at two wheeler headgear and kneepads, as well as two wheel transporters of various kinds.
What could Saudi Aramco do to get lots of stable investors? How about, along with the dividend, or an instant value coupon at any online brokerage account, dividend funded, "free"-like longevity medications in the mail to anyone who owns shares.
Some longevity drugs are are super affordable from alibaba.com like amazon-for-companies made-in-china.com. Rapamycin is only $80-194/Kg. At 21mg/24 hours as a daily delicious candy, that is just 7 grams annually, or about $1.40. If fluororapamycin works, and has 100 times dose potency, that is just 1.4 cents annually per Saudi Aramco shareholder.
Nerds are a tiny but separable 2-3mm US candy. There are about 400 nerds in a mailable 4 Oz box that retailed at $1 during 2021. The annual $ to send all the Saudi Aramco shareholders a box of Nerds that makes them live >60% longer with rapamycin is then $1 plus about $1 postage. That can be brought down to 89 cents, including postage with 1/7th lightweight same sized foamed Nerds.
That is a way the Hevolution Foundation could support the wealth stability and beneficial awareness of Saudi Aramaco. Prompt the creation of a longevity technology that all the shareholders get "free".
Also, epigenetic modulator rejuvenation cocktail candies only need to be ingested about once each decade or more often. That is likely another 69 cent postage bonus for owning 1 or more shares. Ask me if you would like more information about this public domain technology product.
New crop technology, sometimes development at plants produces what are defective “twinned” seeds or fruits or grains, something like conjoined mammals, at plants,they can find the genetics of that, then make things like conjoined what, rice, corn, nuts that have double the wheat germ, that is double the embryo mass per grain seed, that then doubles the nutritional quantity of the things wheat germ is noted for like protein and oils at the food. online I wrote at a Bill and Melida Gates Foundation Optimist item reply to anothers comment, “your interest in technology led me to think of an improvement to plant breeding, New crop technology, sometimes development at plants produces what are defective “twinned” seeds or fruits or grains, something like conjoined twin mammals, at plants,they can find the genetics of that, then make things like conjoined twin wheat, rice, corn, nuts that have double the wheat germ, that is double the embryo mass per grain seed, that then doubles the nutritional quantity of the things wheat germ is noted for like protein and oils at the food.
The internet said, at 2023, “Locally grown beans are soft & easy to cook. It’s the imports sold in our markets & supermarkets that needs to be soaked before cooking (at least for 8 hours).” I replied, “very interesting, it makes me think grocery beans could be pressure treated, but still dry for fast soakless preparation, and reduced flatulenece, sort of like instant rice, but cheap, and with the outer membrace on.”
At beans, after harvest, during pre grocery processing, concentrated RF energy at the beans ar processing could replace pre-soak intervals at softening beans from destroying various molecules at the beans that exclude water, presoaked beans are also described online as having reduced flatulence, concentrated RF energy at processing could also destroy those flatulence molecules without a water step, also, a very simple approach is to do a water step at pregrocery processing of beans, similar to water treated instant rice
clitoris or penis erection pill, have papaverine, which when injected into the penis causes an erection be an oral pill that is papaverine linked to an antibody or peptide aptamer that localizes to the corpus cavernosum of the penis or clitoral vasocongestive tissues with enough mg to be absorbable at a pill. may be an opiate peptide rather than papaverine linked to the antibody/aptamer peptide, option of anesthetic peptide localizing to ejaculatory nerves or sensation of just the penis, forestalling male ejaculation for 40-240 minutes of continuous male thrusting and sexual motion, a similar antibody or aptamer linked peptide that stimulates vaginal lubricant secretion is also beneficial, as well as a peptide that intensifies orgasm, possibly mcr3, mc4 receptor active bremelanotide at pelvic ganglion, pelvic nerves, ejaculatory intensity/ejaculatory clenching muscle intensification and semen volume heightening peptides
Finding a longevity gene, The molecules at young mouse blood that make old mice live longer are produced from particular genes and alleles, find those genes and allels that produce the highest amount of those molecules at mice, and humans, then with that support, modify mice to have those alleles and see if they live longer with greater healthspan, if they do, and are absent deleterious effects, then make those human alleles part of the enhanced genome of all humans
I asked an electronic amusements group at the local HS, North Bend, Oregon, USA HS with 70 members if they would let me put up a $40 prize for computer programming, They might like this tutorial which permits keyboard scripting/programming https://www.youtube.com/watch?v=eRNv5dGFaas possible version $20 prize for minecraft block scripting, $40 any text computer language scripting, $70 any dynamic web content scripting that stays up a year, $80 at any microsoft office .net programming or other office suite programming that actually gets used, new prize each school quarter. $111 any c++ github new programming once/year prize with any single previous language scripting. $40 for any physical electronics modification or programming like modifying a game controller to pulse twice, or increase automatic pulse rate when a button is pressed, and $80 for parts/meters preaward, I got a candybar once for being 2nd in a shares portfolio contest. Oh, and $11 bonus, if after writing three text programs in any language they put up their slight skills at fiverr.com for $5, cautioning fiverr clients they are HS students, just beginning.
engineering, chemistry, computer ic, computer fab, longevity, longevity technology, treon, treon verdery, physics, lasers, laser, emiconductor, dimension, math, IT, IL, pattern resonance, time travel, chronotechnology, circile, eric the circle, cartoon, healthspan, youthspan, cpi, manufacturing, fiscal, money, software, petroleum, archive at deviantart com user treonsebastia
All technologies, ideas, and inventions of Treon Sebastian Verdery are public domain at JUly 8,2023AD and previously, as well as after that date
at currency acceptor machines like ATMs and grocery auto checkouts a slightly higher functionality currency separator and mover could come from the use of piezoelectricts at the deposited currency stack hypervibrating the top, imaged currency item off the top where, from piezojiggling it comes near enough a mover arm or vacuum multiaperture platen to then traverse to the next location, like a currency holding canister. The piezojiggling could be one size fits all, or better, dynamically adjusted to the mass and texture of each THz scanned, or optically scanned, or ultrasound scanned currency object
Its likely already researched but quantum ghost imaging at landmine detection and removal makes sense. Yay Peace.
as a carefully researched ingredient at prenatal vitamins or supplements, could the active molecules at Tiliacora Triandra reduce or prevent fetal alcohol syndrome, there is a paper titled, “Tiliacora triandra, an Anti-Intoxication Plant, Improves Memory Impairment, Neurodegeneration, Cholinergic Function, and Oxidative Stress in Hippocampus of Ethanol Dependence Rats” At that paper Donepezil also reduces some etoh effects, causing about 2-4 multiples higher visual perception of hippocampus neuron density at both TT(2-3 multiples) and Donezepil(3-4 multiples) Wikipedia notes Donezepil, Aricept, has side effects, and these may preclude use during pregnancy. As an alternative, epigenetic modulators with brain area localization peptides could do what TT and Aricept do during pregnancy, benefitting the fetus.
A name similar to genetic yamaka factors causes cytes to dedifferentiatiate to be stem cytes that can then develop at completely different cyte types of plural types, as a longevity product, epigenetically upregulating the human body’s production of yamaka factor gene activity, possibly with crispr gsDNA demethylation causes a greater amount of circulating, regenerating stem cytes, combining that with epigenetic upregulation of p53 tumor supresssor gene could then reduce risk of cancer even though human cytes and tissues were regenerating and proliferating more rapidly, these two things together then are a longevity and youthspan and healthspan heightening technology.
as an epigenetic modulator drug that heightens longevity and wellness, demethylation with crispr gsDNA, acetylation, or methylation that reduces blood pressure is beneficial, and may be single depot molecule dose.
Sundet, at a study of 40,000 Norwegian twins found that birth year caused heitability of IQ to range from a very high .89/.92 to a kower .23/.29 on a 78 monthish cycle, Norway has extensive lifespan length, and healthspan estimates from medical records, among those being cardiovascular wellness and cancer below median occurences, finding out which, if any of those follow the sundet cycle could be utilized to heighten longevity and wellness
I am unaware of a published source of what I call the Sundet cycle, measurements of EM RF of course make sense, but it is possible, even though the physics is peculiar, that some attribute of angle towards the earth or sun that reoccurs about every 78 months could have an effect, as a possible modulator of this cycle, first demonstrate it at microorganisms and daphnia, then find out if raising these in outer space effects their sundet cycles, further research could have mice raised at different geostationary orbits, and novel pole to pole looping orbits, norwegian latitude orbits, and even, using microgravity stability at the habitat, the ability to fertilize and raise the microorganisms or mice vertical perpendicular to the earths surface and geostationary, like a ferris wheel, as well as horizontal to the Earths surface like a plate, as well as diagonal could be tested, notably, if these change the sundet cycle, then different things that shield or focus sundet cycle effect can be tested and possibly found. While I have no clue what these are, the chronically optimistic might find that there is some attribute of frame of reference, or even relativity concerned. Of course the pragmatic might like testing deep underground locations, as well as microorganisms and mice raised on comfortably climate modified 78 month weather balloons or mouse habitat blimps to see if there is a nearness to matter effect. There may be a previous note about how the sundet cycle might be as brief as 1/40th the length interval of 78 months from a lifespan or gestation interval ratio. That suggests breeding, fertilizing, and developing mice to the equivalent of human 18 would be 8 new mice, with parturition of a fresh cohort every 7 days, for 2 1/2 months, testing mouse cognition, cancer, and social attributes once each 8 days through to mouse adulthood, the most rapid procedure being about 2 months of mouse breeding, 20 weeks of observation, with all 16 cohorts receiving at least 8 weeks of observation and testing each. At .64 mice/day and 4 months, divided with 2 that is less than 3800 at $1/day mouse facility fees utilizing an enriched environment. A full lifespan experiment would be better. The actual procedure would be much more to fund the human scientists, and to cover the mouse facility timed provision of fecund mice and sires.
methylation aging clock reset drugs could opt to find any methylations at DNA that occur with living past the 40s that raise blood pressure, then preferentialize resetting those to the persons own epigenetic form, or an even better epigenetic form, this blocks a rise of blood pressure with age, and increases cardiovascular wellness and healthspan
epigenetic clocks, such as methylation clocks or possible acetylation clocks could be be described as to which epigenetic modifications are both logical necessary, and logical sufficient to be associated with being nonalive within 900 days of the epigenetic clock epigenetic location particular form taking on a particular value. This identifies lethal epigenetic variations that can then be addressed with molecules to be reversed and maintained to be at the the life supporting form at humans of all chronological ages. This preclusion of epigenetic clock terminator forms is then a longevity and and likely also healthspan heightening technology, demethylators like crispr gsDNA, methylators like iRNA, and acetylators could all be actual technological forms of this longevity technology
sensationless injection needles, scalpels, and other medical apparatus are described at other notes as utilizing the numbing effect of vibration, particularly piezoelectrictric ultrasonic vibration from having a battery at a syringe, a tiny 1/4 cent alibaba piezoelectric element, and a 1-1/10th cent alibaba disposable zinc air battery to cause numbness at the injection site from vibration. It could even be that this is a plessant sensation, a new alternative technology is to coat the the injector/slicer metal part with picograms or femtograms of opiate peptides or fentanyl dissolved in eutectic liquid metal such as a gallium indium eutectitic alloy that releases just enough of it at the injection site to cause highly localized numbing, nerve receptor blcoker nonopiate peptide blockers could also be used, increasing comfort. a much less valuable technology, but a different one is to use a peltier element, 1/4-/1/10th of am alibaba 10 cent 10 mm square piezoelectric cooling element to cool the injector or scalpel.
There is a physics demonstrator apparatus that looks like a container with holes drilled in the side with a bunch of separate narrow streams of water flowing out the holes at different curves, this looks similar to a paper towel tube with polka dot holes all over it. As a form of injection needle at immunizations this could deliver vaccine to a wider area and volume, promoting a greater immune response, then, piezoelectrically vibrating such a syringe needle the vaccine could spread or stir to a much wider volume of cytosurfaces at the injection site, if each of these is used together then the amount of $ vaccine utilized could be much less, making vaccines cheaper per dose. This could also work with dental anesthesia injections, piezoelectric vibration could also rapidify dental injection site numbness causing topical gel activity
Nernst batteries are previously described at notes, these use the nernst effect where ion amount difference between two things creates an electrical potential, the ions are of the same kind, which makes it different than a dissimilar electronegativity battery, something like a grid of micro tubules, each with a different geometry, having a vacant space at the top continuously evaporate a solvent like water, creating an ion concentration difference which then makes electricity from the nernst effect, online it says, “2 microvolts per kelvin…[at] previously created thermocells which produce 2 microvolts per Kelvin by using a change in pH”, a square 43 units on a side is 1K multiples of 2millivolts, or 2 volts, millimeter sized tubes, cheap like microbubblewrap, that than produce about 2V at a 4.3 cm sided square battery, stacked 11 high they then produce 22 volts. I think the current depends on how rapidly the ion difference is refreshed.
Replacing element C with other elements of the same column of the periodic table is well known, like silicone polymers, I read that there are variations of the melatonin molecule that are more radioprotective then melatonin, replacing some of the C atoms at those molecules could make new radioprotective molecules which could be measured to see if they have longevization effects
wikipedia has a big list of things activated with mtorc1, and rapamycin is likely to cause greater longevitty from inhibiting mtorc1, inhibiting each of those activated things separately could be tested to see if it causes greater longevity as a way of finding new longevity drugs
Tyrosine message passing and activation causes all kinds of things to happen (wikipedia), they could simply test if tyrosine supplementation heightens wellness, and, possibly longevity, some other things like NMN have a more is better effect, they could test tyrosine
schizophrenia is linked to dopamine receptors which have many types, wikipedia says of a different thing, “Another function of VEGFR-1 may be to act as a dummy/decoy receptor” are there any decoy receptors that have aan effect on reducing schizophrenia while maintainining cognitive function
as an artificial sweetener that causes greater wellness, another artificial sweetner that has a glycemic insulin response is blendable with ribose, a sweet sugar that reduces insulin response, “oral or intravenous ribose administration produces a transient, asymptomatic, and dose dependant decrease in plasma blood glucose to a nadir that is reached 30- to 75-minutes post-administration, before returning to baseline levels in approximately 60- to 120-minutes”
I think upregulating ampk is associated with greater longevity, wikipedia, “the ratio of AMP to ATP molecules gets too high, AMPK will become activated. AMPK will go on to inhibit energy consuming pathways such as protein synthesis.” So drugs that just change AMP to ATP ratios could also favor longevity, peptides are a possibility
mtorc1 is inhibited, causing rapamycin like longevity effects from the protein hypoxia inducible factor one alpha (HIF1A), epigenetic modulation, or peptide drugs that do hif1A things could cause the hypoxia longevity benefits while breathing completely normal amounts of Earth air at humans. hibernating hypoxic mammals and deep sea fish live longer from hypoxia
wikipedia mentions a couple dozen mtorc1 activity cascades and activators, as longevity epigenetic molecules,interference iRNA that methylate these epigenetically could be various different new longevity wellness treatments, with single/depot dosing
autophagy is associated with longevity and wellness, blocking things that block autophagy could heighten longevity, wikipedia, “Upon activation, mTORC1 will phosphorylate autophagy-related protein 13 (Atg 13), preventing it from entering the ULK1 kinase complex, which consists of Atg1, Atg17, and Atg101.[61] This prevents the structure from being recruited to the preautophagosomal structure at the plasma membrane, inhibiting autophagy.” all of those are longevity genetic, epigenetic, and medical molecule longevity possibilities
I think it may be previously at notes, but mtorc1 inhibitors that cause longevization could have much longer duration of activity with some of the element c atoms or hydrogens replaced with silicon, germanium, or halogens at these peptides as a long lasting century or multicentury duration longevity drug
x ray fluorescence is used in mineral prospecting, and handheld x ray fluorescence guns are a known technology that robots could utilize, to make prospecting better, do multi separate wavelength x ray spectrometers exist, and would they be even more effective, as simplistitic as it sounds, many imaging technologies work much better with highly cooled sensors, could a nested peltier effect cooler, similar to those used to make near liquid nitrogen temperatures be small, light, and cheap enough to rpovide a few doublings of sensitivity, noting the detector could be at a liquidless thermoslike dewar around it, once cold, it would stay highly sensitized with minimal extra energy, this could possibly also work with human or robot xrf guns, I just read online that peltier elements are used at xrf detectors, Isaac Asimov used to advertise a telescope with a big near spherical reflector near its base, could, perhaps, a robot xrf gun have a bowl shaped x ray retroreflector of say 4/100ths efficiency but 200 multiples greater area than the cooled detector, that would bring 8 times as many echo x rays to the detector heightening effectiveness, if there is such a thing as x ray phosphorescence that might benefit from heightened sensitivity from a sphere reflector, There is an effect where placing a random noise field behind an image causes it to stand out from background more, with greater resolvability, wikipedia does not yet mention a diffuse x ray field accompanying the fluorescence making x ray as a way to generate emerging resolution at an xrf sample, such as at mineral prospecting
D1 specialized neurons with dopamine receptors at particular brain areas like the striatum respond to antipsychotic drugs, using localization moieties or peptides, research drugs that cause those striatum D1 and D2 neurons to have sustained activity, excluding the antipsychotic could then leave the rest of the neurons and regions of the brain at schizophrenics and lab animals to make their effect, if any, on schizophrenia, creating a more functional map of where antipsychotics reduce dopamine activity to reduce schizophrenia, that could be associated with particular symptoms, like audo-like or visual hallucinations, making new molecules with localization to the freshly mapped areas able to treat particular symptoms of schizophrenia,
It is possible dishwashers could air dry faster with coanda air entrainment fans similar to the dyson bladeless fan
at food crops, some flavor neutral version of soapwort, as either a new molecule made at the plant, or placed with the plant at soaking, could cause them to use lesss soak time or preparation time, saving labor, like beans or tubers that soak 20-40 minutes rather than 11 hours
A person mentioned at Bill Gates’ online blog has developed a bean variety/varieties that have just 7% of the presoak and prep time of regular beans, saving fuel, expense, and effort at the developing world, that brings up the possibility of doing similar things at a variety of other foods, it is possible the genetics of hulls, root bark, and seed coatings could be modified or bred to be much thinner or more porous to have this rapid preparation effect. Also, at a variety of tubers and root crops a tuber/potato peeler that has an intrinsically curved shape, that is say 11% longer could reduce food wastage 2-4%, and reduce prep time 8-11%. As another fuel and expense reducing technology, a cutting board, or even cheaper cutting mat could have a stripey reticle on it that guides slicing the peeled tubers to be them smallest delicious size and shape for least fuel use and preparation time, so say a 4 cm cube becomes a 2 cm cube, to make it so the amount of slicing remains constant or decreases, the cutting knife could have two linear spaced blades, say 2 cm apart, better alloys, or newer more affordable forms of laser peening could make the two blades 2-7 times thinner, making cutting as easy, or easier than a single bladed knife, at the entire world, food processors, sometimes similar to cuisinart appliances could be reengineered to reduce prep times and food wastage
semiconductor lasers that do laser peening, mach piezoelectric, transparency grating, metamaterial concentrator funnel, cooling channels at stripey laser flats with fluid between polygons
semiconductor lasers that can cut multicm metal plate are published as of 2023AD, these may be sufficient to do laser peening, even more value effective semiconductor lasers could be made with variations on those, or completely new, cheaper semiconductor lasers, it is possible that the laser peening shockwave moves either at the speed of sound, or faster, putting a piezoelectric vibrator that can move at the speed of speed of sound or higher, and vibrating the workpiece at a mach number could cause the combined velocity of the shockwave to be higher force, making less powerful lasers able to do laser peening, zooming the work piece on a vibrating holder moving towards the laser pulse combines with the shockwave directional motion to velocitize the shockwave to double its velocity, or double its distance, also, the laser could have gratings that cause metal to be much more transparent, which then at actual grooved or tesselated gratings on a semiconductor active layer cause higher semiconductor (rather than metal) transparency reducing warmth build up and heightening efficiency, thinking of a tesselation of laser diodes, like an array, the spaces between the diodes could have channels between them with an immersive fluid between them, or a liquid metal and insulator side layer for heat removal, another possible enhancement is using say a published 100K concentrator optical metamaterial with open areas between the tesselated polygons to take an ordinary 12W/40$ semiconductor laser diode and, with an array of 84 of those make 1KW of laser energy, metamaterial concentrated to a million watts at a narrow beam output that then is concentrated with other optics to make laser peening Watt intensity pulses for about $3700 of semiconductor laser diode material
tiny MEMS accelerometers record minute personal deviations of wobble at a riding bicyclist that are possibly unique to each person. A locator tag on the bike could tell not only where it was, but if a different than usual person was riding it, this could be used to track missing bicycles, as well as diagnose wellness variations at persons using the bicycle, or other exercise technology, to inform them of wellness change,
as a longevity technology finding epigenetic modulators that reduce or block calcification, such as calcification of the pineal gland as well as arteries could cause continued high production of melatonin from the pineal gland and reduce blood pressure from atrtery flexibility throughout living, other drugs are also possible
at published material, just changing peptides to be halogenated, without specific halogenation of particular peptides causes 1.5 multiples greater dose potency, possibly previously written is halogenating specific more electronegative amino acids at peptides such as longevity peptides at particular molecule locations to enhance function, ethynlization of particular, especially electropositive peptides is also possible to enhance the effectiveness of peptide drugs
people, previous to using rapamycin or other longevity molecules could get a cheek swab or nonfluoridated toothbrushing saliva sample to get a saliva or blood sample, which could then be compared to the lab results after they had been taking rapamycin or other molecules for a while, perhaps some of these molecules will also be found to have epigenetic benefit
noting that halogenation of peptides heightens their dose potency 1.5 times, it is possible that halogenation of nucleotides like RNA like at iRNA drugs and iRNA epigenetic modulators could heighten their dose potency as well.
resveratrol has some published data as a longevization molecule, with three OH groups it may have greater benefit with ethynylization of haologenation or dimerization
UV tanning beds may be associated with enhanced mood, and are published as associated with enhanced sleep quality, I do not know if this goes all the way to euphoria or not, duplicating that, without photoaging is beneficial with molecules, as another technology a semiconductor UV LED pad appliable to the buttocks or stomach could cause mood enhancement from the tanning bed effect without photoaging at the face and hands, it could also work on the thighs
possibly there is some way to heighten emulsifier output at all meals, heightening lipid soluble vitamin and other beneficial molecule absorption, wikipedia says, “lipid-soluble nutrient. This process in the human body involves secretion into the small intestine of pancreatic enzymes and bile, which facilitates emulsification and micelle formation required for absorption of lipophilic substances.[47] Food intake (and the presence of lipids) stimulates bodily biliary excretion of bile acids and greatly enhances absorption”
2023AD aging may have caused greater contrast agent like effect on IQ, with higher IQ being more traceable to brain areas, neuron types, and genetics among the particularly old at 2023AD, that makes it possibly easier to find the beneficial and mass inducible genetics that cause higher IQ at persons of all ages among the much older 2023AD persons such as 80 year olds with high IQ
I saw a blonde woman with large nude breasts on Quora and urged her to post more attractive, sexy images, “Thanks for posting, I hope you are a natural blonde, and you and a friend got to have sex or masturbate while taking the image to make it extra sexy. You make me start to get hard. So if you you like delighting people that like breasts and getting guys erect Keep posting!” I also wrote, “Glad to see you sharing your sex pleasure with another at the animated gif. I hope you came, and even had a rememberable orgasm, I only remember about one orgasm I ever had, it would be a good thing to learn to be able to do. I can remember some sex movements and percussions though a little. Glad you are a hotwife and get to be with all the men and women you want.” at another of her posts
a person wrote about photons as a math physics thing, and I wrote, “can a photon of a full wavelength, which would usually be a frequency but is now different, then be a unitary event as a soliton, or the opposite of a soliton, a hyperabsorbable non trigonometric wave?
I’m opposed the the antinausea drug scopalamine as it is used among scientists to induce amnesia in lab mammals, and the thought of recreational travelers forgetting their voyages seems nonoptimal, noting that it is possible that the receptors that scopalamine functions on, at the particularly very specific brain and neuron localizations possible with aptamer peptides could cause an antinausea effect while permitting full remembering capability.
wikipedia talk page comment, “== Unless the Noether theorem is wrong it would be great to have a version of this article at simple.wikipedia.org ==
I wanted to comprehend the theorem while being kind of unsophisticated. a simple wikipedia article could be created about Noether's theorem could be created right here: https://simple.wikipedia.org/w/index.php?title=Noether%27s_theorem&action=edit&redlink=1
I'm clueless, but it seems like it might be wrong based on what are described at wikipedia as time crystals, as well as even possibly turing machines, and any simple motional computing device”
the beneficial to giure out heritability cycle published at a paper written Sundet, a study of norwegian twins and IQ, could be approached to see if there is a sundet cycle with plants, video sorting of seeds, like peas, or leaf variability shapes, could find out if plants have the same .29-.89 heritability of some characteristics based just on what year or month they are seeded, planted, sprouted, measured, if the sundet cycle can be found using software learning imaging of seeds or leaves genetic heitability amount (are they smooth peas, or very high heritability cycle interval smooth peas) plants could then be usilized at outser space to find out where the sundet cycle comes from.
The enthynyl group may be what causes 200 times less first pass hepatic metabolism at the liver of ethynyl estradiol, perhaps ethynylizing rapamycin would increase plasma life and dose postency as well as a longevity drug.
epigenetic modulation is published as reversing aging, with just methylation factors, it makes sense and has likely occured to many others that the 5-7 different kinds of epigenetic modulation could each have their own rejuvenation epigenetic modulator group, ubiquination and acetylaion are two others i have heard of, “continuously expressing only OSK, leaving out the oncogene c-MYC [7, 8]. In the optic nerve, for example, expression of a three Yamanaka factor combination safely resets DNA methylomes and gene expression patterns, improving vision in old and glaucomatous mice via a largely obscure mechanism that requires TET DNA demethylases [8]. Numerous tissues, including brain tissue, kidney, and muscle, have now been reprogrammed without causing cancer [7, 8, 22, 24, 25]. In fact, expression of OSK throughout the entire body of mice extends their lifespan [26]. Together, these results are consistent with the existence of a “back-up copy” of a youthful epigenome”
Notably the OSK epigenetic modulator group is just published as doing age reversal on fibroblasts, OSK and others tested on a variety of other tissue cytes, and whole mice makes sense, the paper suggests whole mice, neurons, cardiomycytes, vascular epithelia and artery cytes, islet cytes, liver cytes, lung cytes, and mitochondria/mtDNA and the cytes most aged at supercentenarians would be beneficial, it is possible three of the tested ccombo epigenetic modulators that are already drugs, parnate(tranylcypromine), an antidepressant, valproic acid, and forksolin could be looked up to see if they are previously published at having epigentic benefit to other cyte tpes, as well as the the other numbered research molecules, valproic acid, parnate and forskolin are published as neuron beneficial, notably as epigenetic modulators they would be taken for just a/few 72 hour occurences per decade, and not as continued doses, entertainingly, a houseplant and decorative plant or tree, and agricultural perennial could be tested with the 2023AD published epigenetic youthful rejuvenation OSK, or even OSK ingredient group as a single epigenetic modulator photosynthetic organism rejuvenator
wikipedia, “Galectin-8 controls mTOR causing its inactivation and dissociation from damaged lysosomes” more of that protein could have longevization effects, as a gene therapy, or beneficial allele variant
Beneficial breathable gas short peptide longevity technology, a short longevity peptide like 4 amino acid AEDG, or two amino acid epithalon could have its hydrogens replaced with longer alkanes, where the alkanes are short halogenated chlorofluorocarbon branches molecules like the breathable halothane anesthetic molecules, a sufficient number od these halothanes replacing hydrogens at peptides could make the peptide have an inhalable gas form at some warmth less than 30 degrees C, this is also true for synthetic amino acid versionions of AEDG epithalon and two amino acid thymalin peptide that have even less mass with full longevization and healthspan benefitting activity. It is even possible that an aimno acid form with a hydroxrl and amino group with a glycine or alanine like polyhydrocarbon could have the polyhardrocarbon be replaced with a polyhalogenated halothane like C atom sequence that has surplus lift to gaseous form that is shared at the entire amino acid sequence making it breathable as a form of new drug dosing of peptide drugs, particularly longevity drugs, it is also possible an inhalebale form of MDMA is possible with similar halothanation of hydrogen locations.
As a possible disease reducing mosquito or tsetse fly volatile attractant, hlogenated, or halothaned hydrogen replacement or methyl group replacement could be used on insect trap attractants that lure malaria and other illness mosquitos and flies to insecticide
CES2 gene product could be beneficial at an enhanced human genome, the internet says, “role of CES2, the researchers genetically engineered mice to overexpress CES2 in their livers and found that the protein improved overall metabolic health. Mice lost weight and had greater endurance and better glucose tolerance than non-genetically engineered mice. The CES2-overexpressing mice could also run faster and for a longer time than their non-genetically engineered counterparts.”
au automated produce produce and fruit harvesters including flying drone fruit and produce harvesters lasers could actively resurface the fruit contact gripping surface several times per day, optimizing contact adhesiveness and structure shape, pulsing dirt or water or gunk off, making it so the fruit and produce contacting surfaces had maintened freshnesss and successfullness, high qualty image recognition could aim the lasers at just the fruit and produce contact touch elements omitting lasers being beamed anywhere ner other items or people, it is also possible that pelitier elements coud condense water from the ir on a cool surface and then rinse or wash autonomomous robots parts and suufrace contact areas.
an artificial sweetener that might reduce glycemic response, compared with some 2022AD atificial sweeteners published as producing averse glycemic response, there is the sweetness of cinnamon bark, cinnamon extract capsules are advertised as reducing glycemic response, it is possible there is a cinnomon based molecule that tastes sweet, while reducing deleterious glycemic response
genetics may be associated with both dental beauty as well as resistance to tooth decay, epigenetic modulators could reduce tooth decay and heighten the beauty of developing teeth, iRNA methylation, and crispr gsDNNA demethylation are possible technologies, as could be new acetylators.
breast implant injected gel component miniblobs could be responsive to high magnetic fields, maing them externally steerable for most beautiful placement
Flavorless or pleasantly flavored nutrient such as physiologically available Fe, other elements, vitamins, and beneficial phytochemicals and other beneficial molecules are producible with microencapsulation of the anemia and birth defect and schizophrenia preventing Fe supplement and other supplements, that makes it such that at the tobgue and saliva there is an absence of Fe flavor, or other supplement flavor from the microencapsulation coating lasting two hours at saliva, with the two hour duration precluding the generation of an aftertaste, while the microencapsulation material is very rapidly dissolving at stomach pH, or also metabolized with stomach enzymes, one very very affordable possibility is custom molecular mass starches and glucose polymers as microencapsulation coatings that preclude Fe and other supplement flavor perception, that absence of flavor then favors supplementing a wider variety of foods with Fe and other supplements
could reactive phosphotidylizing phospholipids not attached to anything as reactive groups then attatch to a variety of things at the body, not yet studied, that then heighten wellnesss, heighten longevity, or treat or cure illness, this is kind of a phospholipids turning down imuunoreactivity on particular things to provide benefit, or turning down immunoreactivity to many things generically to ceate benefit,
A published longevizing gene, “a centenarian-enriched intronic variant residing in a cell-type specific enhancer in SMAD3, a critical receptor-regulated TGF- β signal transducer, was identified. This non-coding SMAD3 variant (rs8040709) altered binding of ELK1, a member of the ETS family of transcription factor important for enhancer activity in certain cell types, resulting in reduced SMAD3 expression. Analysis of the variant in cell types derived from gene edited iPSCs demonstrated the variant reduced SMAD3 expression, senescence and inflammation in endothelial cells. In addition, heterozygosity in SMAD3 improved healthspan and reduced senescence in the Ercc1-/Δ progeroid mouse model of accelerated aging. Taken together, these experiments demonstrate that variants in a cell type specific enhancer of SMAD3 resulted in reduced expression, senescence and inflammation and contributes to human longevity. Thus, SMAD3 represents a validated targeted for drug development for extending human healthspan.”
photonic or acoustiv forms that have physics resonace physical motion which jiggles them so much they cease working, could be used on the mitochondria or other organelles of nerve cetyes at various locations of the body or the cns to very greatly reduce atp energy production that is used to power ant aversive sensation, or any nociception nerve or other cyte, precluding the production of any aversive stimulus, nociception, or discomfort such as a nerve cytes and tissues at arthritic tissues then having arthritis sensation turned off. mitochondria at possibly multihundred nanometer to micrometer size have photonic as well as acoustic resonce frequency wavelengths at physics resonance, those resonance wavelengths could be meamed into cytes and tissues, and body structures and organs, or, different than a beam transmitted as a field effect, it is possible a wide range of nerve and other cyte effects can be caused from resonantly modulating mitochondrial activity, ranging from rapid anesthesia effects, to preclusion of sensation effects
those microthin layers on air conditioer radiators, if made out of some other metal, and semiconductor laser peened to be 14-19 stronger, or greater at their strength could be used at vehicle surfaces and bumpers to absorb collision force with minimal size, mass/weight, and vehicle styling compromise. like a multileaved roller embossed box beam tesselation that gets laser peened. This benefits people from making a bumper that might have previously been a 5 mph bumper actually be a 80-90mph force dissipation bumper saving lives during collisions it also makes a 1/2 cm side of vehicle side collision bumper be able to be as effective a bumper as, possibly a 14-19 multiples thicker 9cm thick collapsible metal plate bumper. These could also be used at two wheeler headgear and kneepads, as well as two wheel transporters of various kinds.
What could Saudi Aramco do to get lots of stable investors? How about, along with the dividend, or an instant value coupon at any online brokerage account, dividend funded, "free"-like longevity medications in the mail to anyone who owns shares.
Some longevity drugs are are super affordable from alibaba.com like amazon-for-companies made-in-china.com. Rapamycin is only $80-194/Kg. At 21mg/24 hours as a daily delicious candy, that is just 7 grams annually, or about $1.40. If fluororapamycin works, and has 100 times dose potency, that is just 1.4 cents annually per Saudi Aramco shareholder.
Nerds are a tiny but separable 2-3mm US candy. There are about 400 nerds in a mailable 4 Oz box that retailed at $1 during 2021. The annual $ to send all the Saudi Aramco shareholders a box of Nerds that makes them live >60% longer with rapamycin is then $1 plus about $1 postage. That can be brought down to 89 cents, including postage with 1/7th lightweight same sized foamed Nerds.
That is a way the Hevolution Foundation could support the wealth stability and beneficial awareness of Saudi Aramaco. Prompt the creation of a longevity technology that all the shareholders get "free".
Also, epigenetic modulator rejuvenation cocktail candies only need to be ingested about once each decade or more often. That is likely another 69 cent postage bonus for owning 1 or more shares. Ask me if you would like more information about this public domain technology product.
New crop technology, sometimes development at plants produces what are defective “twinned” seeds or fruits or grains, something like conjoined mammals, at plants,they can find the genetics of that, then make things like conjoined what, rice, corn, nuts that have double the wheat germ, that is double the embryo mass per grain seed, that then doubles the nutritional quantity of the things wheat germ is noted for like protein and oils at the food. online I wrote at a Bill and Melida Gates Foundation Optimist item reply to anothers comment, “your interest in technology led me to think of an improvement to plant breeding, New crop technology, sometimes development at plants produces what are defective “twinned” seeds or fruits or grains, something like conjoined twin mammals, at plants,they can find the genetics of that, then make things like conjoined twin wheat, rice, corn, nuts that have double the wheat germ, that is double the embryo mass per grain seed, that then doubles the nutritional quantity of the things wheat germ is noted for like protein and oils at the food.
The internet said, at 2023, “Locally grown beans are soft & easy to cook. It’s the imports sold in our markets & supermarkets that needs to be soaked before cooking (at least for 8 hours).” I replied, “very interesting, it makes me think grocery beans could be pressure treated, but still dry for fast soakless preparation, and reduced flatulenece, sort of like instant rice, but cheap, and with the outer membrace on.”
At beans, after harvest, during pre grocery processing, concentrated RF energy at the beans ar processing could replace pre-soak intervals at softening beans from destroying various molecules at the beans that exclude water, presoaked beans are also described online as having reduced flatulence, concentrated RF energy at processing could also destroy those flatulence molecules without a water step, also, a very simple approach is to do a water step at pregrocery processing of beans, similar to water treated instant rice
clitoris or penis erection pill, have papaverine, which when injected into the penis causes an erection be an oral pill that is papaverine linked to an antibody or peptide aptamer that localizes to the corpus cavernosum of the penis or clitoral vasocongestive tissues with enough mg to be absorbable at a pill. may be an opiate peptide rather than papaverine linked to the antibody/aptamer peptide, option of anesthetic peptide localizing to ejaculatory nerves or sensation of just the penis, forestalling male ejaculation for 40-240 minutes of continuous male thrusting and sexual motion, a similar antibody or aptamer linked peptide that stimulates vaginal lubricant secretion is also beneficial, as well as a peptide that intensifies orgasm, possibly mcr3, mc4 receptor active bremelanotide at pelvic ganglion, pelvic nerves, ejaculatory intensity/ejaculatory clenching muscle intensification and semen volume heightening peptides
Finding a longevity gene, The molecules at young mouse blood that make old mice live longer are produced from particular genes and alleles, find those genes and allels that produce the highest amount of those molecules at mice, and humans, then with that support, modify mice to have those alleles and see if they live longer with greater healthspan, if they do, and are absent deleterious effects, then make those human alleles part of the enhanced genome of all humans
I asked an electronic amusements group at the local HS, North Bend, Oregon, USA HS with 70 members if they would let me put up a $40 prize for computer programming, They might like this tutorial which permits keyboard scripting/programming https://www.youtube.com/watch?v=eRNv5dGFaas possible version $20 prize for minecraft block scripting, $40 any text computer language scripting, $70 any dynamic web content scripting that stays up a year, $80 at any microsoft office .net programming or other office suite programming that actually gets used, new prize each school quarter. $111 any c++ github new programming once/year prize with any single previous language scripting. $40 for any physical electronics modification or programming like modifying a game controller to pulse twice, or increase automatic pulse rate when a button is pressed, and $80 for parts/meters preaward, I got a candybar once for being 2nd in a shares portfolio contest. Oh, and $11 bonus, if after writing three text programs in any language they put up their slight skills at fiverr.com for $5, cautioning fiverr clients they are HS students, just beginning.
engineering, chemistry, computer ic, computer fab, longevity, longevity technology, treon, treon verdery, physics, lasers, laser, emiconductor, dimension, math, IT, IL, pattern resonance, time travel, chronotechnology, circile, eric the circle, cartoon, healthspan, youthspan, cpi, manufacturing, fiscal, money, software, petroleum, archive at deviantart com user treonsebastia
All technologies, ideas, and inventions of Treon Sebastian Verdery are public domain at JUly 8,2023AD and previously, as well as after that date
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