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What happens if I mix ascorbic acid with glycerol?

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Fred

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Dec 19, 2009, 5:46:00 PM12/19/09
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What happens if I mix ascorbic acid with glycerol?
And then apply this mixture to the skin? Will the ascorbic acid
(vitamin C) get absorbed through the skin? Will the glycerol(or
glycerin) react with the ascorbic acid and produce new compounds?

Madalch

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Dec 21, 2009, 4:41:35 PM12/21/09
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I don't know how well ascorbic acid absorbs through the skin, but it
won't react with glycerol. Unless you're planning to boil it with
acid or something.

Bill Penrose

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Dec 21, 2009, 7:23:14 PM12/21/09
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It won't likely be absorbed through the skin. What you'll have is a
harmless mixture that should prevent scurvy when taken in small
amounts. It will also make you stick to everything in sight.

Dangerous Bill

Dirk Bruere at NeoPax

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Dec 22, 2009, 6:19:19 PM12/22/09
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Generally if you want (smallish) molecules to be zapped through the skin
a 70:30 soln of DMSO:water does the trick.


Dirk

http://www.transcendence.me.uk/ - Transcendence UK
http://www.theconsensus.org/ - A UK political party
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Androcles

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Dec 22, 2009, 7:26:38 PM12/22/09
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"Dirk Bruere at NeoPax" <dirk....@gmail.com> wrote in message
news:7pd2fe...@mid.individual.net...

> Bill Penrose wrote:
>> On Dec 19, 3:46 pm, Fred <infinitebram...@gmail.com> wrote:
>>> What happens if I mix ascorbic acid with glycerol?
>>> And then apply this mixture to the skin? Will the ascorbic acid
>>> (vitamin C) get absorbed through the skin? Will the glycerol(or
>>> glycerin) react with the ascorbic acid and produce new compounds?
>>
>> It won't likely be absorbed through the skin. What you'll have is a
>> harmless mixture that should prevent scurvy when taken in small
>> amounts. It will also make you stick to everything in sight.
>>
>> Dangerous Bill
>
> Generally if you want (smallish) molecules to be zapped through the skin a
> 70:30 soln of DMSO:water does the trick.
>
http://en.wikipedia.org/wiki/Osmosis
In general, these membranes are impermeable to organic solutes with large
molecules, such as polysaccharides, while permeable to water and small,
uncharged solutes. Permeability may depend on solubility properties, charge,
or chemistry as well as solute size.

Salmon Egg

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Dec 23, 2009, 12:05:27 AM12/23/09
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Ascoglycerin? :=)

Bill

--
An old man would be better off never having been born.

Mark Thorson

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Dec 23, 2009, 3:52:04 PM12/23/09
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Androcles wrote:
>
> In general, these membranes are impermeable to organic solutes with large
> molecules, such as polysaccharides, while permeable to water and small,
> uncharged solutes. Permeability may depend on solubility properties, charge,
> or chemistry as well as solute size.

DMSO has the unusual property of making the
skin permeable to rather large molecules.
This caused a problem at Crown Zellerbach
where they were researching things to do
with DMSO. They found it was a great
solvent for cleaning glassware, but they
were dealing with a lot of tars from wood
distillation and soon discovered that
substances which are not usually considered
poisonous become poisonous when carried
through the skin by DMSO.

Fred

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Dec 31, 2009, 1:56:24 AM12/31/09
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The part about certain non-poisonous substances become poisonous as
they enter the body through the skin with the help of DMSO is
something I am looking into very closely. I think this has to do with
these substances bypassing the digestive tract and/or the liver. Some
substances just don't get absorbed at all by the intestine and will
just pass through. The liver with also block, detoxify, or convert
certain chemicals into other less dangerous chemicals. DMSO aided
absorption through the skin bypasses all of this and so I think this
is why certain non-toxic substances become dangerous, right?

Androcles

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Dec 31, 2009, 2:46:15 AM12/31/09
to

"Fred" <infinit...@gmail.com> wrote in message
news:f23fb815-6724-4d05...@s3g2000yqs.googlegroups.com...

Snipping has the unusual property of making the
skin permeable to rather large misattributions.
This caused a problem at Crown Usenet


where they were researching things to do

with snipping. They found it was a great


solvent for cleaning glassware, but they

were dealing with a lot of idiots with wooden
blockheads and soon discovered that
posts which are not usually considered


poisonous become poisonous when carried

through the skin by snipping attributions.

Dirk Bruere at NeoPax

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Dec 31, 2009, 11:38:32 AM12/31/09
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Probably.
But that applies even more to injections.
Consider the use of DMSO to be the equivalent of an injection into the
bloodstream.

--

Mark Thorson

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Dec 31, 2009, 4:33:06 PM12/31/09
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Dirk Bruere at NeoPax wrote:

>
> Fred wrote:
> >
> > The part about certain non-poisonous substances become poisonous as
> > they enter the body through the skin with the help of DMSO is
> > something I am looking into very closely. I think this has to do with
> > these substances bypassing the digestive tract and/or the liver. Some
> > substances just don't get absorbed at all by the intestine and will
> > just pass through. The liver with also block, detoxify, or convert
> > certain chemicals into other less dangerous chemicals. DMSO aided
> > absorption through the skin bypasses all of this and so I think this
> > is why certain non-toxic substances become dangerous, right?
>
> Probably.
> But that applies even more to injections.
> Consider the use of DMSO to be the equivalent of an injection into the
> bloodstream.

Yes, that's right. The skin normally protects you
from all sorts of stuff you might touch, but DMSO
changes that. Because of it's unusual ability to
penetrate tissues, it has another serious hazard.
It can penetrate the lens of the eye, causing it
to cloud up -- that's a cataract. DMSO itself is
otherwise non-toxic, but it needs to be treated
with considerable respect. Apparently, it is an
effective liniment for joint pain, but I'd never
use it for that. I've seen bottles of it in
so-called "health food" stores, and I wouldn't
use it for anything, even if I trusted the purity
of what's in those bottles.

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