My car has a leak in the heater core, thus the hot air smells like
anti-freeze. Can it stay like this for long with no ill effects?
Thanks in advance...
Matt Graham
m...@druhi.att.com
How much do you drink??
The major anti-freeze component is ethylene glycol HOCH2-CH2OH. When introduced
into the human body, it is a substrate analog of ethanol and will be acted on
by the alchohol dehydrogenase (ADH) enzyme, which will convert it to HO2C-CO2H
(oxalic adic) over a few steps. Oxalic acid is poisonous.
But, if you drink lots of alcohol, a competitive inhibition "race" is started
between the ethylene glycol --> oxalic acid and the ethanol --> acetaldehyde
reactions, giving your body more time to purge the oxalic acid.
This is simular to the mechanism for methanol poinsoning (but the end product
is formaldehyde).
Note: I am an organic chemist -- any biochem types out there feel free to
add to/correct the above statements.
Oh, I would doubt that you are getting enough ethylene glycol to be dangerous,
but if you are getting hangovers after driving for a while, I would become
concerned. (Not to mention that anti-freeze hasn't been cheap since the
ethylene glycol plant blew up, but that is another story).
--> --> Dale UVa (ds...@virginia.edu)
Ethylene Glycol poisoning can be lethal. I would consider death a serious
effect. Some people do think the treatment is fun, though, since it
consists of being given intravenous alcohol.
David Rind
ri...@popvax.harvard.edu
Propylene glycol is supposedly almost as good as ethylene glycol for
automotive purposes. As I recall, it's slightly better as a coolant,
but not quite as good as an antifreeze; but the difference shouldn't
matter except in the most extreme of climates.
Unlike ethylene glycol, which is deathly poisonous, propylene glycol is
non-toxic. I understand it's actually used in certain food items. Of
course, a propylene-glycol-based antifreeze would probably have various
additives (rust inhibitors, etc.), so I wouldn't go out and quaff large
quantities of the stuff.
Also, propylene glycol does not have ethylene glycol's sweet smell. I
have never tried drinking it, so I can't tell you if it's sweet-tasting.
Presumably, the lack of an odor -- together with its non-toxicity --
would make propylene glycol much less of an "attractive nuisance" to
dogs and cats who might come across a radiator leak or the aftermath of
a sloppy radiator flush-and-refill.
--
Rich Wales <wa...@CS.UCLA.EDU> // UCLA Computer Science Department
3531 Boelter Hall // Los Angeles, CA 90024-1596 // +1 (213) 825-5683
Oh so very true. Ethylene Glycol can be lethal in as little as 1/2 an
ounce. As I believe it has already been stated, the breakdown product is very
poisonous. I would not take to drinking it. Although, I would like to know
what it feels like to get intravenously drunk. :)
-Oz
Sorry; rigor mortis is incompatible with relaxation. Antifreeze isn't
cyanide, but it isn't Gatorade either. Don't drink it, don't let animals
drink it, wear safety glasses, wash it off your skin, and don't put it in
a plastic bag and sniff it as though it were airplane glue. Here are the
gory details.
There are three routes of exposure: ingestion, inhalation, and skin contact.
According to the references readily at hand (the 1984 NIOSH Registry of
Toxic Effects of Chemical Substances, the U.S. Coast Guard CHRIS handbook
Chemical Hazards, and the Material Safety Data Sheet for Prestone put out
by Union Carbide of Canada), ethylene glycol, the major ingredient in
antifreeze, is a Class 2 toxin by oral ingestion. Class 2 means "slightly
toxic." Acute toxicity has been observed at levels as low as roughly
710 milligrams per kilogram of body weight in humans. The LD50 in small
lab animals is on the order of a few grams per kilogram.
It can cause narcosis, dizziness, nausea, and headache upon excessive
inhalation; and brain, kidney, and liver damage; inebriation; and coma
or death upon ingestion, depending on intake. Through contact it is
only an irritant. As of the mid-80s it was not considered a human
carcinogen or teratogen.
At first, 710 mg/kg seems like a lot. HOWEVER, these references hint that
at levels well below acute systemic toxicity, and/or after delays, there
could be brain, kidney, and liver damage. No quantitative information was
available.
Via inhalation, the Threshold Limit Value (ceiling never to be exceeded in
industrial exposure lest the regulators getcha) is 50 ppm vapor in air or
10 mg per cubic meter particulate in air. Since the original poster wanted
to know if a persistent antifreeze stink in his car would be bad for him,
the answer is "kinda" (it's a red flashing warning about the health of
the car as well...)
Ethylene glycol is rated as a mild primary skin irritant and a moderate
eye irritant. This jibes with personal experience; it's never irritated
my skin but I take precautions to keep it out of my eyes.
Animals are at risk. It supposedly tastes good to animals, and they just
lap it up. They have a lot fewer kg to absorb each mg than you do.
Bye-bye, Fido. Hose down your antifreeze spills.
Here are the emergency first aid procedures from the MSDS. (Any company
will be glad to give you an MSDS upon request these days.) Skin and
eye contact: flush with water. If swallowed, induce vomiting at once;
give one or two glasses of warm water, milk, or salt water. Keep
victim warm and call physician immediately.
Testimonial to the lawyer glut: The above was performed as a nonsponsored
coffee-break public service and does not necessarily represent the official
position of anybody. All claims are disclaimed, in hoc signo vinces,
e Unibus plurum, and other express or implied attorneyspeak hereintofore.
--Joe
"Just another personal opinion from the People's Republic of Berkeley"
Doug
--
<><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><>
Doug Fierro
<<The only guarantee in life is that you will die>> fie...@uts.amdahl.com
UNIX division
<><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><><>
According to the 6th ed of SAX
ethylene glycol (aka 1,2-ethanediol) has a TLV of 100 parts per
million and is " Very tox[ic] in particulate form upon
inhal[ation]."
___________________________________________________________
|Mike Whitbeck | whit...@unssun.unr.edu |
|Desert Research Inst. | whit...@wheeler.wrc.unr.edu |
|POB 60220 | whit...@sanjuan.UUCP |
I would say that propylene glycol is "relatively" non-toxic when
compared to say, ethylene glycol. The oral LD50 for propylene glycol is
probably ten times that of ethylene glycol. One of the metabolic products
of propylene glycol is lactic acid. It does not require too much imagination
to realize that an excess of lactic acid produced by ingestion of quantities
of propylene glycol is not without harmful effects.
>I understand it's actually used in certain food items.
In *small* quantities, though. Propylene glycol is commonly used
in soft drinks to facilitate the stable solution of flavoring ingredients.
>Also, propylene glycol does not have ethylene glycol's sweet smell. I
>have never tried drinking it, so I can't tell you if it's sweet-tasting.
Propylene glycol has virtually no odor or taste for most people.
Larry Lippman @ Recognition Research Corp. "Have you hugged your cat today?"
VOICE: 716/688-1231 {boulder, rutgers, watmath}!ub!kitty!larry
FAX: 716/741-9635 [note: ub=acsu.buffalo.edu] uunet!/ \aerion!larry