With nearly $290M of new funding for seven years to research institutions around the country, the National Institutes of Health renewed its commitment to the Adolescent Brain Cognitive DevelopmentSM Study (ABCD Study) the largest long-term study of brain development and child health ever conducted in the United States.
All data access information is documented on the NDA ABCD Featured Dataset page and includes pointers to an external ABCD Study wiki where data release notes and general information about the data resource are provided. All users should review the release notes for detailed information on the released data. Note that with the change to how release notes are made available, they will be updated regularly and thus users are advised to check -notes/start-page.html for the most up-to-date information. Release notes for qualified users only (i.e., non-public) are available at =2147. The 5.0 data ontology and dictionary can be viewed at -dict.abcdstudy.org/.
The table below highlights key differences between the 4.0 and 5.0 data releases. Note that the Data Exploration and Analysis Portal (DEAP) has been decommissioned as of June 1, 2023. In addition, study creation no longer works with how the data are shared this year. We anticipate reinstating it with the 6.0 data release.
This special issue of ChildArt introduces the intersection of the arts and neuroscience through an overview of the ABCD Study. It presents some of the data from the study, as well as other research looking at the impact of the arts on child development. The issue combines the work of experts in neuroscience, world renowned artists, specialists in child development, and others. Topics covered include the juncture between the arts and human culture, the developing adolescent brain, the interaction between cultural and biological processes and artistic creation, the interface of the arts and science as a multisensory experience, insights from the neuroscience of dance and music, and more. We hope that this special issue will stimulate creativity and innovation in research on the impact of the arts on child development as well as encourage researchers to leverage the ABCD Study data to advance research on a wide range of other topics.
Please note: The ABCD study is assessing brain development in children throughout adolescence, while tracking social, behavioral, physical and environmental factors that may affect brain development and other health outcomes. Screen time is only one of many measures evaluated as part of the study protocol.
For an overview of how the ABCD study got started, see article co-authored by NIDA Director Dr. Nora Volkow, NIAAA Director Dr. George Koob, NINDS Director Dr. Walter Koroshetz, and other NIH scientists: The conception of the ABCD study: From substance use to a broad NIH collaboration, published in Developmental Cognitive Neuroscience.
Our data are publicly shared with eligible researchers with a valid research use of the data at a research institution. All sharing of the data, as well as access to it, is handled by the NIMH Data Archive (NDA). The process for accessing the data starts by creating an account at NDA (if you do not already have one), and then requesting access to the ABCD Study data through the dashboard there ( _permissions.html).
This will generate a Data Use Agreement/Certification (DUC) that you can fill out with your research aims. The DUC also outlines all of the rules you must follow when using ABCD data. You will then sign this document electronically, and submit it to an Institutional Signing Officer at your institution for their signature as well. The exact office that handles these agreements differs by institution; for example, at UCSD this is handled by the Office of Contracts and Grants Administration.
You will then upload this document signed by you and your institution to the same dashboard you started the process with, and NDA will review your application. You will then be able to download the data from NDA, and I would encourage you to learn more about the process at our Wiki: You can find a bit more about the data sharing timelines on our website here: -sharing/. If you have any questions along the way, the NDA help desk (nda...@mail.nih.gov) can help answer any further questions.
Our data are publicly shared with eligible researchers with a valid research use of the data, and who are at an institution with an active Federal Wide Assurance, which many international institutions have ( =bsc). Users from many other countries have successfully accessed and published with the ABCD Study data.
If you go this route of having one DUC with collaborators listed, be sure that all collaborators also have NDA accounts, and list their email addresses associated with their NDA account, because that way when the DUC is approved by NDA, those people will be able to access the downloads themselves.
As a practice the ABCD Coordinating Center (CC) and Data Analysis, Informatics, and Resource Center (DAIRC) do not provide letters that could be seen to endorse specific applications or projects that propose secondary analyses of the ABCD Study data.
While we do not offer specific endorsements, we do offer our commitment to maintaining open lines of communication with the larger scientific community and to do whatever we can to ensure that they are able to acquire the information about the ABCD Data Resource that they may need to address their specific aims.
We recommend users refrain from using Safari on MacOS to download the ABCD 5.0 data files as this can result in an incomplete download. Instead, we recommend using Chrome or Firefox to download these data on MacOS.
Predefined packages (e.g. trial-level behavioral data) are in the raw data section in near the bottom of the ABCD featured dataset page. All raw data can be found under the Measures tab of the 5.1 Data Release. To download the timeline followback (TLFB) raw data, for example, go to the Measures tab, click on ABCD Raw Data for the Timeline Followback (TLFB) Calendar. Follow the NDA directions to download the data (abcd_tlfb_tlbd01). Click the option to download associated files in order to download the tlfb-raw-data-concatenated.csv file.
You can find our protocol on the scientist section of our website here ( ), but in general we are not able to share the actual measures outside of the study, as many are proprietary. You can read a lot more about the protocol development in a special issue of DCN on the ABCD Study here: -cognitive-neuroscience/vol/32. Finally, you can also generally find the questions asked and answer options as part of the protocol on our new interactive Data Dictionary (https:// data-dict.abcdstudy.org/) and find more information on the ABCD Wiki:
The NIH Brain Development Cohorts (NBDC) Biospecimen Access Program launched in September 2023. This program provides the research community access to biospecimens collected from the Adolescent Brain Cognitive Development Study (ABCD Study) participants through an X01 resource access mechanism.
If you are interested in using ABCD Study biospecimens in your research, please start by reviewing the NBDC Biospecimen Access Program website for more information about the ABCD Study, the available resources, the process for applying to the X01 Resource Access Program, and Frequently Asked Questions.
Series that pass raw QC may have some minor issues but are considered acceptable for processing. Because of relatively tight brain coverage for dMRI and fMRI acquisitions, the superior or inferior edge of the brain is sometimes outside of the stack of slices. We term this field of view (FOV) cutoff. Except in extreme cases, dMRI and fMRI series are not excluded at raw QC for mild to moderate FOV cutoff. Such cases are also not recommended for exclusion by default. In the tabulated imaging data, brain regions outside the FOV have missing values, but other regions remain usable.
The automated post-processing QC metrics include measures of superior and inferior FOV cutoff that can be used to exclude participants with FOV cutoff from analyses. _structure.html?short_name=abcd_auto_postqc01
Raw gradient tables are available from theABCD Collection page. Refer to specific notes on how to use these in the Fast Track Guidelines. In the minimally processed data, gradient tables are provided per scan, adjusted for head rotation.
For imaging data from Philips scanners, the dMRI acquisition is split into two series because of a limitation of the Philips platform. Both scans have the same phase-encode polarity. They are meant to be concatenated together. In other rare cases, multiple dMRI scans may have been acquired, due to acquisition problems in early scans. For the minimally processed data, one scan is selected for each session based on QC ratings, except for Philips scanners, in which case two are selected for packaging and sharing. All scans are available as raw DICOM files via fasttrack data sharing.
These series have been run through standard modality-specific pre-processing stages including conversion from raw to compressed files, distortion correction, movement correction, alignment to standard space, and initial quality control (refer to MRI Quality Control (QC) Release Notes). This is to enable researchers to use the ABCD neuroimaging data in their own processing pipelines more quickly and efficiently than starting with raw data. Note that minimal processing is identical for rs-fMRI and task-fMRI and does not include analysis-specific pre-processing steps (e.g. removal of initial TRs, normalization by mean, etc.). Researchers intending to use minimally processed data should take note of the appropriate acknowledgment language to include in any public disclosure of results (refer to -archive.nimh.nih.gov/abcd/results). The available minimally processed files are detailed in the Other Imaging Instruments Release Notes.
Preprocessed imaging data are packaged in archive files (tgz) for each image series containing BIDS formatted directory trees and NIfTI format data files (software to share preprocessed data: _016016; consistent with BIDS specifications version 1.1.1: _spec.pdf). Imaging metadata derived from the original DICOM files are packaged along with each preprocessed data series as JSON files. The minimally processed T2w data are resampled into voxel-wise alignment with the T1w, which is rigid-body resampled into alignment with an atlas.
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