You may applied 3rd party themes on Windows XP and Windows Vista. You can do the same on Windows 7. The theme manager (implemented in uxtheme.dll, themeui.dll and themeservice.dll) is responsible for drawing non-client parts of every window displayed within Microsoft Windows 7 according to the styles defined in your active theme.
Before you can load a theme, Windows will verify if it has been digitally signed by Microsoft. Otherwise, the system will block you from installing it. However, you can work around this problem by modifying your system files, particularly the uxtheme.dll. Before, users had to boot into Safe Mode and manually replace them. Thankfully, there is now an easier way to do this.
The third-party theme will not work without installing the theme patcher. You can find some theme patchers on the internet and here is how to install Ultra UXTheme Patcher. Most of the time you just need to click the Next button as you would install a normal application, sometimes you need to install it manually.
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