Hi all,
CSEM v2.4 is online now.
- Replaced the Fenwick tree like structure with a linear structure to
speed up CSEM
- Added user-friendly reminders if CSEM guesses that users forget to
compile the codes
- Added '--no-extending-reads' option to 'run-csem' to disable extending
reads
- Added '--tag-align' option to 'csem-generate-input' to support tagAlign
format files as inputs for downstream ChIP-Seq peak callers
You can find the source codes here
http://deweylab.biostat.wisc.edu/csem/
CSEM is a ChIP-Seq multi-read allocator. CSEM stands for ChIP-Seq
multi-read allocation using Expectation-Maximization. It is RSEM's brother
and part of the following paper:
[Chung, D., Kuan, P. F., Li, B., Sanalkumar, R., Liang, K., Bresnick,
E., Dewey, C. N., Keles, S. (2011). Discovering transcription factor
binding sites in highly repetitive regions of genomes with multi-read
analysis of ChIP-seq data. _PLoS Computational Biology_,
__7__(7):e1002111.](
http://www.ploscompbiol.org/article/info%3Adoi%2F10.1371%2Fjournal.pcbi.1002111)
Best,
Bo