I have it running on an RPI4. I ended up just installing everything from scratch. Most of the work is just trying to figure out the pulseaudio stuff. QUISK is also fussy with the detected audio. If I were you I would :
install new os on the RPI4
install quisk, wspr and fldigi from the software center in the preference area
install pulseaudio controls from software center
I learned, at least for me, the pulse audio controls have to always be started first and left open. Then a cmd window to start quisk. I have different configs of quisk stored for different setups, they are:
Speakers: uses and external usb audio card to drive speakers and a mic (I could not get the RPI on board audio out to work right)
digital: no external speakers
Phone: Uses a USB headset
There is various timing on what USB devices are plugged in when for which config. :-P It is kludgy but I know the routine. I would give you my image but I have been using the radio also as a computer and it has personal stuff on it...
Rich
PS the RPI4 is MUCH fast than the 3b I started with