calculating percentage variance explained

[Cynthia]

Hello,

If the max lod score in a single qtl scan is 5.11 and the number of samples is 176. how do I calculate the percentage of variance explained?

Cynthia

[Karl Broman]

The formula is:

1 - 10^(-(2/n)*LOD)

where n is the sample size. See pg 77 of the R/qtl book (http://www.rqtl.org/book).
(The 4th page in the pdf of ch 4, which is available online: http://www.rqtl.org/book/rqtlbook_ch04.pdf)

So about 12.5%:

1 - 10^(-(2/176)*5.11)

karl

> --
> You received this message because you are subscribed to the Google Groups "R/qtl discussion" group.
> To unsubscribe from this group and stop receiving emails from it, send an email to rqtl-disc+...@googlegroups.com.
> To post to this group, send email to rqtl...@googlegroups.com.
> Visit this group at http://groups.google.com/group/rqtl-disc.
> For more options, visit https://groups.google.com/d/optout.