Metamorph Imaging Software
Garland Flugum
The MetaMorph Microscopy Automation and Image Analysis Software automates acquisition, device control, and image analysis. It easily integrates dissimilar fluorescent microscope hardware and peripherals into a single custom workstation. The software offers many user-friendly application modules for biology-specific analysis. Two complementary packages, MetaFluor software for fluorescence ratio imaging, and MetaVue software for basic image acquisition and processing, are included in the portfolio.
Automates the acquisition of multiple images and then stitches them seamlessly together. Ideal for large tissue samples, this ensures reproducibility while taking the guesswork out of tiling experiments.
Tools for multidimensional visualization including stacks of sequential images, multiple Z-sections, wavelengths, time points, and positions. Data can be rendered for 3D isosurface viewing and rotation.
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Combining the most flexible and powerful tools for image acquisition, processing, and analysis, MetaMorph imaging systems offer a complete solution for even the most demanding live-cell imaging needs.
Acquisition & Device ControlMetaMorph device control makes acquisition fast and easy, allowing the integration of automated microscopes and a variety other hardware devices into a single, intuitive acquisition interface.Image Display & ProcessingImage display and processing tools are crucial for performing accurate image analysis, and MetaMorph offers a complete toolbox of advanced features in this area, from background subtraction and shading correction, to morphology filters and an interactive 4D Viewer.Image AnalysisMetaMorph offers analysis tools to handle everything from simple intensity logging to advanced morphometry analysis, colocalization, FRET, 3D measurements, and more. Optional Application Modules perform assay-specific analysis, such as counting nuclei or assessing cell cycle phases, in a simple wizard-like interface.CustomizationPowerful and easy-to-use journal (macro) functions in MetaMorph enable users to further automate acquisition, processing, and common analysis routines, while custom toolbars and menus provide users quick access to commonly used menu options, taskbars, and journals.
The MetaMorph Microscopy Automation and Image Analysis Software is a very well established software in biology since more than 20 years to automate acquisition, device control, and image analysis.
It is characterized by its very wide availability to easily integrate dissimilar fluorescent microscope hardware and peripherals into a single custom workstation. Wellknown for its powerful and robust device and camera streaming capabilities, that accelerate image capture rate and simultaneously transfers images to memory during acquisition, MetaMorph captures dynamic cellular events for applications such as live cell/kinetic imaging.
MetaMorph benefit from a flexible, guided user interface to easily capture basic and/or complex acquisition sequences.
The software offers a complete toolbox of features to display, process, analyses, visualize 2D to 6D images.
MetaMorph handles everything from simple intensity logging to advanced morphometry analysis, colocalization, FRET, 3D measurements, and more. Several optional modules such as application modules allow the user to perform assay-specific analysis, such as counting nuclei or assessing cell cycle phases, in a simple wizard-like interface.
Powerful and easy-to-use journal (macro) functions in MetaMorph enable users to further automate acquisition, processing, and common analysis routines.
Acquisition & Device Control
Complete microscope and peripherals automation
Compatibility with many commercially available microscopes, cameras, spinning disk, TIRF, laser launches, photomanipulation module, and more
Streaming devices capabilities
Powerful and robust multi-dimensional imaging tool easily adapted to any acquisition protocol
Acquisition of multiple images with seamless stitching with the scan slide module, ideal for large tissue samples, to ensure reproducibility while taking the guesswork out of tiling experiments.
Digital image analysis is an essential component of modern Optical Microscopy Imaging, the core is very well equipped in terms of image analysis software. The personnel of the core can provide technical support to the users in the form of training and assistance with the design and troubleshooting of image analysis strategies. Many of the software packages have the ability to write custom applications via scripting language. The core staff can assist users by writing custom applications as part of collaborative projects.
The core has at least 7 seats for offline image analysis copies of this program, 3 at the MRB and 4 at the GNL. This software is the main tool used by the core for image processing and analysis of 2D and 3D image data sets as well as time series and spectral images. Metamorph has a wide range of built in functions ranging from the most basic operations to more sophisticated applications such as automated morphometry analysis, automated cell counting, object tracking, movies and FRET analysis. In addition advanced custom applications can be developed using the journal scripting functions, including batch processing of large numbers of images.
This software is used to analyze our live cell and multidimensional experiments. Complex 2D and 3D time series with multiple locations can be easily visualized. This program has a great collection of features for advanced image processing and analysis with a friendly user interface.
This free software is very popular as it can be downloaded and installed in any personal computer. The core staff can provide basic technical support with the use of this software. Metamorph however is a more powerful tool and is the preferred option.
This is one of the best software packages available for processing and analysis of 3D and 4D images. The core has two licenses for this program, one at the MRB and one at the GNL. This software can easily generate astonishing volume renderings of 3D data sets as well as dramatic animations of 3D rotations, however this software also provides a collection of advanced tools for image quantifications and analysis such as 3D colocalization analysis, 3D object tracking, Filament tracing, 3D image segmentation and automatic object measurements.
This a true 3D deconvolution package for image restoration. Based on measured point spread function constrained iterative algorithms. 3D deconvolution uses a mathematical algorithm to correct the autofocus blur of 3D image datasets based on the known properties of the imaging system. The result are images in which the contrast and resolution are greatly enhanced. It can be used to improve confocal images or to generate 3D image reconstructions based on z-series of wide field images. The core has one license running in the MRB.
Volocity 3D image analysis and Volocity image restoration (3D deconvolution). This is a 3D image analysis and rendering package of functionality similar to Imaris, the 3D image deconvolution module is similar to the functionality provided by Huygens. Several license seats are available to OMC users in the GNL image analysis core.
High content image base citometry analysis. Acapella is used for cell based automated image analysis of large volumes of data, this is the software that powers Perkin Elmer's high content imaging platforms such as the Opera and Operetta systems. Acapella is accesible to OMC users at the GNL image analysis core.
This is a multifunctional system that include software and hardware components designed to handle, organize and analyze large quantities of images. This system is intended to handle the images generated by the GNL Imaging Cores. It provides storage and database organization of image files from almost just any format available. Also, provides image visualization and manipulation features for quick access and examination of datasets as well as advanced tools for image analysis. The advanced tools include: Acapella high content citometry analysis, Volocity 3D image anal
MetaMorph for Olympus converts your biological experiment into a publishable result. Built on the market-proven MetaMorph platform, this powerful package offers functionality, flexibility, and stability that meet the most demanding image acquisition and analysis needs. With over 10,000 publications citing MetaMorph, you can rest assured that your imaging needs will be met now and in the future.
MetaMorph for Olympus device control makes acquisition fast and easy, allowing the integration of IX2 and BX3 microscopes and a variety of other hardware devices into a single, intuitive acquisition interface.
Image display and processing tools are crucial for performing accurate image analysis, and MetaMorph for Olympus offers a complete toolbox of advanced features in this area, from background subtraction and shading correction, to morphology filters and an interactive 4D Viewer.
MetaMorph for Olympus offers analysis tools to handle everything from simple intensity logging to advanced morphometry analysis, colocalization, FRET, 3D measurements, and more. Optional Application Modules perform assay-specific analysis, such as counting nuclei or assessing cell cycle phases, in a simple wizard-like interface.
Powerful and easy-to-use journal (macro) functions in MetaMorph for Olympus enable users to further automate acquisition, processing, and common analysis routines, while custom toolbars and menus provide users quick access to commonly used menu options, taskbars, and journals.
MetaMorph for Olympus offers eleven user-friendly Application Modules for biology-specific analysis. Each Application Module features a dedicated dialog box with intuitive setting selections, improved segmentation through adaptation to local content, and both field and cell-by-cell data logging. After analysis is complete, users can interactively view tabular and image results side by side. Application Modules may be incorporated into macros for increased customization and automation of analysis. All Application Modules are validated in-house and with third-party collaborators.
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