My point was that a well thought-out pattern would be applicable to a larger audience (result in larger volumes). One of the ideas inherent in the pattern I showed is that improved power/ground also needs bypass and filter caps. I'm not sure how you are planning to add those into this pattern, or how you plan to connect the top foil to the corresponding pin on the DIP socket. I can't comment on the cost of these boards, and certainly the amount of drilling required for prototype boards is a factor - which is probably why most prototype boards I've bought "off-the-shelf" have pretty uneven, inconsistent, holes and nothing through-hole-plated. Every time I have to use one of those, I think about trying to recreate the boards I used to use (shown above).
If you're expecting to make changes, you might want to consider wire-wrap. But, if you're not setup for that or haven't spent time doing wire-wrap, that would be a hurdle. Tools are more expensive, and (of course) learning to use them correctly is important, but you have a much better chance of (successfully) making changes later.
Sounds like you are planning a large and complex project. It will be interesting to see the finished product.