AS or AA: To be or not to be

[CharlesBoyo]

Hello all.

I had a conversation with a friend yesterday that I would like to
throw to the house.

We all know the scourge that is Sickle Cell Anaemia. The sickling of
red blood cells most evident in the folks with the SS genotype. It is
also a well known fact about the ways to avoid this genotype for ever
occurring in future generations.

This topic is in two parts.

1. With the recent research findings in this area, it appears that
sicklers are better managed and thus have lower mortalities than
before. How valid is this statement and how much comfort can be
reasonably drawn from it?

2. How many people bother to ask about genotypes when they begin
relationships? At what point is this even relevant? And how many
people would be willing to risk AS/AS or AS/SS relationships?

In theory, the chances of an SS in a AS/AS match is 1 in 4. For the AS/
SS match, that's a 1 in 2. But since each child is a unique
occurrence, these theoretical figures could be meaningless. I know a
couple (AS/AS) that have four SS and one AA.

What do you think?

[Olufunm...@gmail.com]

i think it is safer to always ask those type of questions even in
simple friendships so that it doesnt become an issue later.
i churches now before a wedding is conducted partners must present
there bloodgroup and HIV test result

[CharlesBoyo]

Geez!

I wonder how a conversation like this could end:

A: Hello, my name is Seun.
B: Hi mine is Funmi.
A: Pleased to meet you. What's your blood group, genotype, rhesus
factor and HIV status?

:)

[Adeyemi Adeleke]

Hello,

Its quite true that mortality rate of sickle cell victims has reduced and that is just based on awareness and knowledge of everybody.

In respect to asking your partner about her genotype and all that, i think its seriously immature not to ask. I believe you need to know so that nobody will have a reason in the future to say otherwise.

Information at the begining is important and vital. It can keep the relationship on forever.

As for me, i will ask my girlfriend anything and everything; she can ask also and i will be obliged to answer.

have a great day.

CCNA, SCSA 9, NACA, NACP, JNCIA-M

[Olufunm...@gmail.com]

yea it would really be funny, the person might even get angry, but if
you consider him /her getting angry now than later , you wont mind