| Allergy, Asthma and Immunology
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Predictive model to differentiate chronic histaminergic angioedema and chronic spontaneous urticaria with angioedema.
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por iva...@gmail.com Jun 16, 2024
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Láinez-Nuez A, Salas-Parra G, Juárez-Guerrero A, Picó-Peris A, Baeza ML. J Allergy Clin Immunol Glob. 2024 May 9;3(3):100278. doi: 10.1016/j.jacig.2024.100278. Abstract Background: Chronic histaminergic angioedema (CHA) may be classified as a separate acquired angioedema (AE) or as an endotype of chronic spontaneous urticaria (CSU). A recent study suggested them to be independent pathologies. Objective: We carried out an exhaustive analysis between CHA and AE-CSU to explore the possible differentiation between them on the bases of a series of predictors. Methods: An observational, retrospective, cross-sectional, and exploratory study was designed. Fifty-six CHA and 40 AE-CSU patients were included. Data were extracted from the year before and year after time of diagnosis. A predictive model was generated by logistic regression, and its discriminatory power was assessed using the area under the receiver operating characteristic curve...
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Allergic Conjunctivitis Management: Update on Ophthalmic Solutions.
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por iva...@gmail.com Jun 16, 2024
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Leonardi A, Quintieri L, Presa IJ, LLoves JM, Montero J, Benítez-Del-Castillo JM, Lestón FJS, González-Mancebo E, Asero R, Groblewska A, Kuna P. Curr Allergy Asthma Rep. 2024 Jun 13. doi: 10.1007/s11882-024-01150-0. Abstract Purpose of review: The aim of this review, is to present an updated revision of topical management of SAC and PAC, based on the available scientific evidence and focused on the impact of ophthalmic solution formulations on eye surface.
Recent findings: Physicians treating ocular allergy should be aware of tear film and tear film disruption in SAC and PAC, and how eye drop composition and additives affect the physiology of the allergic eye. Seasonal and perennial allergic conjunctivitis (SAC and PAC) are the most frequent causes of ocular allergy (OA), and both conditions are underdiagnosed and undertreated...
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