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Identifican nuevo tratamiento potencial para las alergias alimentarias
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por iva...@gmail.com Jul 13, 2024
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Un estudio de la Universidad de Michigan (EEUU) ha identificado un nuevo tratamiento potencial para las alergias alimentarias en la inulina, una fibra vegetal natural que se utiliza habitualmente como suplemento, prebiótico en refrescos, sustituto de edulcorantes y para otros productos y fines.En lo que parece ser un avance importante que ofrece la promesa de alivio a las personas que sufren alergias alimentarias en todo el mundo, el artículo publicado en Nature Materials describe el éxito de la inmunoterapia oral basada en gel de inulina para detener las reacciones alérgicas...
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Allergy, Asthma and Immunology
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Multiplex LAMP assay for detecting the prevalent species of dust mites Dermatophagoides farinae and Dermatophagoides pteronyssinus in the domestic environment
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por iva...@gmail.com Jul 13, 2024
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Shuai, Y., Xue, Q., Tu, H. et al. Sci Rep 14, 16156 (2024). https://doi.org/10.1038/s41598-024-66043-8
Abstract
Dermatophagoides farina (D. farinae) and Dermatophagoides pteronyssinus (D. pteronyssinus) are the prevalent kinds of house dust mites (HDMs). HDMs are common inhalant allergens that cause a range of allergic diseases, such as rhinitis, atopic dermatitis, and asthma. The epidemiology of these diseases is associated with exposure to mites. Therefore, in the present study, a method named multiplex loop-mediated isothermal amplification (LAMP) was developed to detect environmental dust mites...
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Unraveling the Molecular Threads: A Comprehensive Review of the Pathogenesis and Therapeutic Insights Into Allergic Rhinitis.
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por iva...@gmail.com Jul 13, 2024
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Sharma A, Deshmukh P, Jain S, et al. Cureus 16(7): e64410. doi:10.7759/cureus.64410 Abstract Allergic rhinitis (AR) is a prevalent inflammatory disorder of the nasal mucosa, triggered by allergen exposure and characterized by symptoms such as sneezing, nasal congestion, itching, and rhinorrhea. This comprehensive review aims to unravel the molecular mechanisms underpinning AR, exploring the pathogenesis from allergen recognition to chronic inflammation and tissue remodelling. Central to the disease are immunoglobulin E (IgE)-mediated hypersensitivity reactions, involving key inflammatory mediators and cellular players such as mast cells, eosinophils, and T cells...
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Childhood infections, asthma and allergy trajectories, and chronic rhinosinusitis in middle age: A prospective cohort study across six decades
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por iva...@gmail.com Jul 13, 2024
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Perret JL, Idrose NS, Walters EH, et al. Allergy. 2024; 00: 1-15. doi:10.1111/all.16184
Abstract Introduction Evidence on the early life risk factors of adult CRS, and the history of asthma and allergies across the life course, is limited. Aim To investigate relationships between respiratory infective/allergic conditions in childhood, and asthma and allergies across the life course and CRS in middle age. Methods Data were from the population-based Tasmanian Longitudinal Health Study (TAHS) cohort, first studied in 1968 when aged 6–7 years (n = 8583) and serially followed into middle age (n = 3609). Using a well-accepted epidemiological definition, participants were assigned a CRS-severity subtype at age 53: no sinusitis/CRS (reference); past doctor diagnosis only; current symptoms without doctor diagnosis; and doctor-diagnosed CRS with current symptoms...
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