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Allergy, Asthma and Immunology Application of Nanoparticles for Immunotherapy of Allergic Rhinitis por iva...@gmail.com Nov 26, 2024 Li K, Jin J, Yang Y, Luo X, Wang Y, Xu A, Hao K, Wang Z. Int J Nanomedicine. 2024 Nov 18;19:12015-12037. doi: 10.2147/IJN.S484327.  Abstract:  Graphical abstract Allergen Immunotherapy (AIT) is the only etiological therapeutic method available for allergic rhinitis (AR). Currently, several options for AIT in the market, such as subcutaneous immunotherapy (SCIT) and sublingual immunotherapy (SLIT), have different routes of administration. These traditional methods have achieved encouraging outcomes in clinic. However, the side effects associated with these methods have raised the need for innovative approaches for AIT that improve safety, shorten the course of treatment and increase local drug concentration. Nanoparticles (NPs) are... Continuar Leyendo Efficacy of probiotics as adjuvant therapy in bronchial asthma: a systematic review and meta-analysis por iva...@gmail.com Nov 26, 2024 Balan, D., Baral, T., Manu, M.K. et al. Allergy Asthma Clin Immunol 20, 60 (2024). https://doi.org/10.1186/s13223-024-00922-7 Abstract Background Asthma is a chronic, heterogeneous disease characterized by airway inflammation. Asthma exacerbations significantly increase the disease burden, necessitating new therapeutic approaches. Emerging evidence suggests probiotics, through the gut-lung axis, may benefit asthma management by modulating immune responses and reducing inflammation. Methods This systematic review and meta-analysis adhered to PRISMA guidelines and was registered with PROSPERO (CRD42023480098). A comprehensive search of PubMed, Scopus, Web of Science, and Embase was conducted up to March 2024. Inclusion criteria encompassed randomized controlled trials (RCTs) evaluating probiotic interventions in asthma patients. Statistical analysis was done using RevMan 5.3, with odds ratios (OR) and 95% confidence intervals (CI) calculated, and heterogeneity assessed using I2 statistics. Results Forest plot for asthma control test Twelve RCTs, comprising 1401 participants, met the inclusion criteria. The probiotic strains investigated included... Continuar Leyendo